If you are planning a quick getaway from Newton to Biloxi, you are looking at a straightforward 157.5-mile journey that typically takes about 3 hours and 24 minutes to complete. This route serves as a practical day trip, allowing you to transition from central Mississippi down to the coast without needing an overnight stay. You should budget approximately $24 for fuel to cover the distance comfortably. Navigating through the Southeast, the drive connects inland areas to the Gulf Coast via a mix of state and national highways. It is a reliable, highway-focused route that gets you to your destination efficiently, making it an excellent choice for a weekend coastal escape.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
78.8 miles from Newton, MS
A natural place for your longest stop of the day
, about 1h 47m into the drive
.
Main Roads
Road
Distance
Duration
MS 15
49.1 mi
1h 13m
US 49
41.9 mi
49m
Lance Corporal Roy M Wheat Memorial Highway
34.8 mi
37m
Biloxi-D'Iberville Scenic Expressway
20.5 mi
24m
US 98
3.2 mi
4m
I 110
3.2 mi
4m
South Main Street
1.9 mi
4m
Division Street
0.6 mi
1m
Longest stretch:
MS 15
— 49.1 mi, about 1h 13m
Turn-by-Turn Driving Directions
Step-by-step road directions between Newton, MS and Biloxi, MS.
1
Start on South Main Street
1.9 mi·4 min·South Main Street
2
At end of road, turn right onto MS 15
49 mi·1 hr 13 min·MS 15
Use the right lane.
3
Take the exit
0.3 mi·40 sec
Use the slight right / right lanes.
4
Merge onto I 59
35 mi·37 min·Lance Corporal Roy M Wheat Memorial Highway
Use the straight / slight right lanes.
5
Take the exit onto US 98
3.2 mi·4 min·US 98
Toward US 98 East: Lucedale, MobileUse the straight / slight right lanes.
6
Take the exit
0.3 mi·44 sec
Toward US 49: Wiggins, Gulfport, Mississippi Gulf CoastUse the straight / slight right lanes.
7
Keep slight left at fork
0.2 mi·27 sec
Toward Multi Purpose Center, HattiesburgUse the slight left / slight right lanes.
8
Turn right onto US 49
42 mi·49 min·US 49
Use the straight lane.
9
Take the exit
0.8 mi·1 min
Toward MS 67 South: D'Iberville, Biloxi
10
Continue on MS 67
20 mi·24 min·Biloxi-D'Iberville Scenic Expressway
11
Continue on I 110
3.2 mi·4 min·I 110
12
Take the exit
0.4 mi·47 sec
Exit 1cToward Division Street
13
Turn left onto Division Street
0.6 mi·1 min·Division Street
14
Turn right onto Main Street
0.5 mi·1 min·Main Street
15
Turn left onto Howard Avenue
91 ft·3 sec·Howard Avenue
16
Arrive at destination
Howard Avenue
Trip Plan
To make the most of this 157.5-mile trip, aim to depart early in the day to navigate the highway segments while traffic is manageable. Planning for just one stop is usually sufficient to handle the 3-hour and 24-minute travel time comfortably. Since you are spending roughly $24 in fuel, topping off your tank before leaving Newton ensures you won't have to worry about finding a station during the longest 49.1-mile stretch on MS 15. Keep an eye on your speed as you transition between the state and national highways, as speed limits can fluctuate near the coastal approach. The flexibility of a single-day itinerary means you can easily adjust your pace to arrive in Biloxi whenever your schedule permits.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 78.8 miles from Newton, MS, or about 1h 47m into the drive.
The longest continuous stretch on this route runs about 49.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 35 miles or 53m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 78.8 miles or 1h 47m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 47m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Newton, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Newton, MS
This is one driving day of about 157.5 miles and 3h 24m.
Your first comfortable stop window is around 35 miles from Newton, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS 15 for about 49.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 11
5 decision points cluster between mile 1.9 and 89.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
1.9 mi into trip|~4m in|MS 15
At end of road, turn right onto MS 15
Lane positioning matters here
Use the right lane.
7
86.1 mi into trip|~1h 55m in|US 98
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 98 East: Lucedale, Mobile
7
89.3 mi into trip|~2h in
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 49: Wiggins, Gulfport, Mississippi Gu...
9
89.6 mi into trip|~2h in
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward Multi Purpose Center, Hattiesburg
6
89.8 mi into trip|~2h 1m in|US 49
Turn right onto US 49
Lane positioning matters here
Use the straight lane.
Fuel & Cost
Regular Gas
$23.79 one way
$47.57 round trip
$3.84/gal25.4 MPG avg55 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$26.11
$52.22
premium
$4.56
$28.27
$56.54
diesel
$5.61
$34.77
$69.55
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$24
Meals
$25–$50
Total
$49–$74
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 55.1 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $17 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
47.3
0
$16.54
$7.56
Efficient EV
39.4
0
$13.78
$6.30
EV Truck/SUV
63
0
$22.05
$10.08
Gas CO2
55 kg
EV CO2
18 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Newton, MS
Late night
in Newton on Tuesday
Local time
4:09 AM
CDT
Current temp
82°F
Unavailable
Live forecast
Destination
Biloxi, MS
Late night
in Biloxi on Tuesday
Local time
4:09 AM
CDT
Current temp
78°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
4 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 24m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive is defined by a heavy reliance on highway travel, with 75% of your time spent on major thoroughfares like MS 15, US 49, and the Lance Corporal Roy M Wheat Memorial Highway. You will spend a significant portion of your focus on the longest uninterrupted stretch, which covers 49.1 miles along MS 15. Expect a consistent, highway-focused pace that favors steady cruising over technical maneuvering. As you move toward the coast, the road environment shifts to accommodate the flow of traffic toward Biloxi. It is a functional path that prioritizes directness, ensuring you spend less time navigating local backroads and more time on the primary transit corridors.
75% highway — fuel and pacing are the main things to plan.
16 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 49.1 mi on MS 15.
How Hard Is This Drive?
6/10
This is a straightforward highway drive that stays mostly on MS 15 and US 49. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 1.9 miles in near MS 15.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 157.5 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 1.9 miles (MS 15): Lane positioning matters here; at 86.1 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 89.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Newton, MS and Biloxi, MS, road signs point toward Mobile, Gulfport, Mississippi Gulf Coast, Multi Purpose Center and Hattiesburg.
Biloxi is a city in Harrison County, on the Gulf Coast of Mississippi. It's well known for its beaches and nine casinos. It is also home to the "Jefferson Davis Presidential Library and Museum", which serves as a museum of the Confederacy.
Doable as a same-day drive at 3h 24m. Total distance: 157.5 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 24m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (75%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 49.1 miles on MS 15. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Biloxi, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 1.9 miles (MS 15): Lane positioning matters here; at 86.1 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 89.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Possible but tiring. At 3.4 hours each way, an in-and-out day trip would put you behind the wheel for 6.8 hours — manageable with a long break at Biloxi, MS, but most travelers stay overnight.
