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Trip from Olive Branch, MS to Biloxi, MS

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

7h 5m

Distance

365.9 mi

589 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$55

one way

EV Charging

Unknown

Best Time to Leave

Save up to 33 min
4 AM
6h 54m ★
6 AM
7h 5m
8 AM
7h 27m
10 AM
7h 13m
12 PM
7h 11m
3 PM
7h 14m
5 PM
7h 26m
8 PM
6h 58m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in DeSoto County, Mississippi, United States

Olive Branch, MS

Wikimedia Commons

Downtown Biloxi, MS, MS

Biloxi, MS

Wikimedia Commons

Trip Overview

This 365.9-mile drive from Olive Branch, MS, to Biloxi, MS, is best tackled in a single day, taking approximately 7 hours and 5 minutes. The route primarily utilizes I-55 and Highway 49 South, making it a highway-focused journey. With a projected fuel cost of around $56, this trip is quite budget-friendly for a single traveler. You'll experience a straightforward drive across Mississippi, staying within the Southeast region throughout. This is a practical option for those looking to cover ground efficiently between North and South Mississippi.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

2 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

182.9 miles from Olive Branch, MS

A natural place for your longest stop of the day , about 3h 23m into the drive .

Main Roads

Road Distance Duration
I 55 186.1 mi 3h 21m
Highway 49 South 80.3 mi 1h 37m
US 49 44.1 mi 53m
Biloxi-D'Iberville Scenic Expressway 20.5 mi 24m
I 269 9.2 mi 9m
Lance Corporal Roy M Wheat Memorial Highway 7.7 mi 8m
Cockrum Road 6.2 mi 11m
US 98 3.2 mi 4m
Longest stretch: I 55 — 186.1 mi, about 3h 21m

Turn-by-Turn Driving Directions

Step-by-step road directions between Olive Branch, MS and Biloxi, MS.

1

Start on Goodman Road

260 ft · 12 sec · Goodman Road
2

Turn left onto MS 305

6.2 mi · 11 min · Cockrum Road
3

Take the ramp

0.3 mi · 41 sec
Toward Tunica
4

Merge onto I 269; MS 304

9.2 mi · 9 min · I 269; MS 304
5

Take the exit

0.3 mi · 44 sec
Toward I 55 South: Jackson
6

Keep slight left at fork

0.7 mi · 1 min
Toward I 55 South: Jackson
7

Merge onto I 55

186 mi · 3 hr 21 min · I 55
8

Take the exit

0.9 mi · 1 min
Toward I 20 East, US 49 South: Meridian, Hattiesburg
9

Keep slight right at fork onto US 49

0.7 mi · 1 min · US 49
Toward Richland, Hattiesburg
10

Merge onto US 49

80 mi · 1 hr 37 min · Highway 49 South
Use the straight lane.
11

Continue on US 49; MS 42

0.4 mi · 35 sec · US 49; MS 42
Use the straight lane.
12

Continue on US 49; MS 42

1.1 mi · 1 min · US 49; MS 42
Use the straight lane.
13

Take the exit

0.4 mi · 36 sec
Toward I 59 South: New Orleans, Gulf Coast Use the slight right lane.
14

Merge onto I 59

7.7 mi · 8 min · Lance Corporal Roy M Wheat Memorial Highway
Toward Mississippi Gulf Coast Use the straight lane.
15

Take the exit onto US 98

3.2 mi · 4 min · US 98
Toward US 98 East: Lucedale, Mobile Use the straight / slight right lanes.
16

Take the exit

0.3 mi · 44 sec
Toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast Use the straight / slight right lanes.
17

Keep slight left at fork

0.2 mi · 27 sec
Toward Multi Purpose Center, Hattiesburg Use the slight left / slight right lanes.
18

Turn right onto US 49

42 mi · 49 min · US 49
Use the straight lane.
19

Take the exit

0.8 mi · 1 min
Toward MS 67 South: D'Iberville, Biloxi
20

Continue on MS 67

20 mi · 24 min · Biloxi-D'Iberville Scenic Expressway
21

Continue on I 110

3.2 mi · 4 min · I 110
22

Take the exit

0.4 mi · 47 sec
Exit 1c Toward Division Street
23

Turn left onto Division Street

0.6 mi · 1 min · Division Street
24

Turn right onto Main Street

0.5 mi · 1 min · Main Street
25

Turn left onto Howard Avenue

91 ft · 3 sec · Howard Avenue
26

Arrive at destination

Howard Avenue

Trip Plan

Given the 7-hour duration, starting your drive from Olive Branch early in the morning is recommended to avoid fatigue and maximize daylight. With only 2 planned stops, consider spacing them out strategically, perhaps after the longest stretch on I-55. The fuel cost of $56 is manageable, but it's always wise to top off before heading out. Keep an eye on your fuel gauge, especially during the 186.1-mile segment on I-55, as services can sometimes be spaced out on interstates. This route is very doable in one day, offering flexibility in your stopping times.

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 182.9 miles from Olive Branch, MS, or about 3h 23m into the drive.
The longest continuous stretch on this route runs about 186.1 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 80 miles or 1h 32m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 182.9 miles or 3h 23m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 5h 51m

Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Olive Branch, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

+

Pick one backup stop option before the midpoint in case traffic changes your pacing.

Day 1

Settle into the route from Olive Branch, MS

This is one driving day of about 365.9 miles and 7h 5m.

Your first comfortable stop window is around 80 miles from Olive Branch, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on I 55 for about 186.1 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Italian city and commune, located in Tuscany

Mid-route town

Meal stop

Florence, MS

183 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Batesville, MS

Fuel and coffee

A short stop after about 80 miles helps settle the day before fatigue starts building.

Jackson, MS

Meal break

The midpoint is around 182.9 miles from Olive Branch, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 55 if your tank is already low. That segment runs about 186.1 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 19

5 decision points cluster between mile 203.9 and 298 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

6
203.9 mi into trip | ~3h 46m in | US 49

Keep slight right at fork onto US 49 toward Richland, Hattiesburg

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward Richland, Hattiesburg
7
286.4 mi into trip | ~5h 28m in

Take the exit toward I 59 South: New Orleans, Gulf Coast

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Toward I 59 South: New Orleans, Gulf Coast
7
294.5 mi into trip | ~5h 36m in | US 98

Take the exit onto US 98 toward US 98 East: Lucedale, Mobile

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 98 East: Lucedale, Mobile
7
297.7 mi into trip | ~5h 41m in

Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 49: Wiggins, Gulfport, Mississippi Gu...
9
298 mi into trip | ~5h 41m in

Keep slight left at fork toward Multi Purpose Center, Hattiesburg

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left / slight right lanes. Toward Multi Purpose Center, Hattiesburg

Fuel & Cost

Regular Gas

$55.26 one way

$110.52 round trip

$3.84/gal 25.4 MPG avg 128 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.21 $60.66 $121.32
premium $4.56 $65.67 $131.35
diesel $5.61 $80.79 $161.57

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$55

Meals

$25–$50

Total

$80–$105

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 128 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $38 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 109.8 1 $38.42 $17.56
Efficient EV 91.5 1 $32.02 $14.64
EV Truck/SUV 146.4 1 $51.23 $23.42

Gas CO2

128 kg

EV CO2

43 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 14, 2026

Origin

Olive Branch, MS

Evening in Olive Branch on Saturday

Local time

8:27 PM

CDT

Current temp

63°F

Unavailable

Live forecast

Destination

Biloxi, MS

Evening in Biloxi on Saturday

Local time

8:27 PM

CDT

Current temp

65°F

Mostly Clear

SE 5 mph 0% chance Live forecast

55°F

Florence, MS

183 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

2 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

7h 5m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a predominantly highway experience on this 365.9-mile trip, with 95% of the drive on major roads like I-55 and US 49. The longest uninterrupted stretch you'll encounter is a significant 186.1 miles on I-55, so be prepared for sustained highway driving. While largely interstate-based, the transition to Highway 49 South will offer a change of pace as you head toward the coast. The profile suggests a consistent driving experience, ideal for those who prefer straightforward navigation.

95% highway — fuel and pacing are the main things to plan.
26 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 186.1 mi on I 55.

How Hard Is This Drive?

10/10

This is a straightforward highway drive that stays mostly on I 55 and Highway 49 South. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 203.9 miles in near US 49.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 19 significant decision points across 365.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 203.9 miles (US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 286.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 294.5 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Olive Branch, MS and Biloxi, MS, road signs point toward Hattiesburg, Richland, Gulf Coast, Mississippi Gulf Coast, Mobile and Gulfport - among others.

Hattiesburg

203 mi in | ~3h 45m

Richland

203.9 mi in | ~3h 46m | via US 49

Gulf Coast

286.4 mi in | ~5h 28m

Mississippi Gulf Coast

286.8 mi in | ~5h 28m | via I 59

Mobile

294.5 mi in | ~5h 36m | via US 98

Gulfport

297.7 mi in | ~5h 41m

Multi Purpose Center

298 mi in | ~5h 41m

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 7h 5m. Total distance: 365.9 miles.

Family Friendly

Moderate complexity with 2 natural rest stops along the way.

Solo Traveler

7h 5m drive, plan rest stops for pacing.

Frequently Asked Questions

The longest stretch is about 186.1 miles on I 55. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Biloxi, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 203.9 miles (US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 286.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 294.5 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Not recommended in a single day. At 7.1 hours each way, a round trip means 14.2 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Biloxi, MS before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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