This 365.9-mile journey from Walls, MS, to Biloxi, MS, is a solid day trip, clocking in at an estimated 7 hours and 4 minutes of driving time. Primarily utilizing I-55 and US 49 South, this highway-focused drive is designed for efficiency, with 94% of the route on major roads. Your estimated fuel cost for this trip is around $55. With two planned stops, you can break up the journey comfortably. This route stays within the Southeast region, offering a straightforward path down through Mississippi.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
183 miles from Walls, MS
A natural place for your longest stop of the day
, about 3h 23m into the drive
.
Main Roads
Road
Distance
Duration
I 55
193.5 mi
3h 29m
Highway 49 South
80.3 mi
1h 37m
US 49
44.1 mi
53m
Biloxi-D'Iberville Scenic Expressway
20.5 mi
24m
Goodman Road West
8.3 mi
12m
Lance Corporal Roy M Wheat Memorial Highway
7.7 mi
8m
US 98
3.2 mi
4m
I 110
3.2 mi
4m
Longest stretch:
I 55
— 193.5 mi, about 3h 29m
Turn-by-Turn Driving Directions
Step-by-step road directions between Walls, MS and Biloxi, MS.
1
Start on McLemore Drive
14 ft·0 sec·McLemore Drive
2
Turn left onto West Railroad Avenue
270 ft·17 sec·West Railroad Avenue
3
At end of road, turn right onto East Railroad Avenue
0.1 mi·24 sec·East Railroad Avenue
4
Turn left onto 2nd Street
0.1 mi·31 sec·2nd Street
5
Continue on 2nd Street
93 ft·4 sec·2nd Street
6
Turn left onto MS 161
0.4 mi·45 sec·MS 161
7
Turn right onto MS 302
8.3 mi·12 min·Goodman Road West
8
Take the ramp
0.4 mi·54 sec
Toward Jackson
9
Merge onto I 55; I 69
194 mi·3 hr 29 min·I 55; I 69
10
Take the exit
0.9 mi·1 min
Toward I 20 East, US 49 South: Meridian, Hattiesburg
11
Keep slight right at fork onto US 49
0.7 mi·1 min·US 49
Toward Richland, Hattiesburg
12
Merge onto US 49
80 mi·1 hr 37 min·Highway 49 South
Use the straight lane.
13
Continue on US 49; MS 42
0.4 mi·35 sec·US 49; MS 42
Use the straight lane.
14
Continue on US 49; MS 42
1.1 mi·1 min·US 49; MS 42
Use the straight lane.
15
Take the exit
0.4 mi·36 sec
Toward I 59 South: New Orleans, Gulf CoastUse the slight right lane.
16
Merge onto I 59
7.7 mi·8 min·Lance Corporal Roy M Wheat Memorial Highway
Toward Mississippi Gulf CoastUse the straight lane.
17
Take the exit onto US 98
3.2 mi·4 min·US 98
Toward US 98 East: Lucedale, MobileUse the straight / slight right lanes.
18
Take the exit
0.3 mi·44 sec
Toward US 49: Wiggins, Gulfport, Mississippi Gulf CoastUse the straight / slight right lanes.
19
Keep slight left at fork
0.2 mi·27 sec
Toward Multi Purpose Center, HattiesburgUse the slight left / slight right lanes.
20
Turn right onto US 49
42 mi·49 min·US 49
Use the straight lane.
21
Take the exit
0.8 mi·1 min
Toward MS 67 South: D'Iberville, Biloxi
22
Continue on MS 67
20 mi·24 min·Biloxi-D'Iberville Scenic Expressway
23
Continue on I 110
3.2 mi·4 min·I 110
24
Take the exit
0.4 mi·47 sec
Exit 1cToward Division Street
25
Turn left onto Division Street
0.6 mi·1 min·Division Street
26
Turn right onto Main Street
0.5 mi·1 min·Main Street
27
Turn left onto Howard Avenue
91 ft·3 sec·Howard Avenue
28
Arrive at destination
Howard Avenue
Trip Plan
To make the most of this 7-hour drive, consider an early morning departure from Walls to maximize daylight and arrive in Biloxi with time to spare. With two stops planned, aim to take your first break around the halfway point or after the longest stretch on I-55. Keep an eye on your fuel levels, especially during the 193.5-mile segment on I-55, as services can be spaced out. This route is manageable in a single day, so you have flexibility in pacing your stops and enjoying the drive without feeling rushed.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 183 miles from Walls, MS, or about 3h 23m into the drive.
The longest continuous stretch on this route runs about 193.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 80 miles or 1h 31m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 183 miles or 3h 23m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 50m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Walls, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Walls, MS
This is one driving day of about 365.9 miles and 7h 4m.
Your first comfortable stop window is around 80 miles from Walls, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on I 55 for about 193.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 20
5 decision points cluster between mile 0.1 and 298 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
0.1 mi into trip|~0m in|East Railroad Avenue
At end of road, turn right onto East Railroad Avenue
Complex interchange - multiple decisions in a short stretch
7
286.4 mi into trip|~5h 27m in
Take the exit toward I 59 South: New Orleans, Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward I 59 South: New Orleans, Gulf Coast
7
294.5 mi into trip|~5h 36m in|US 98
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 98 East: Lucedale, Mobile
7
297.7 mi into trip|~5h 40m in
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 49: Wiggins, Gulfport, Mississippi Gu...
9
298 mi into trip|~5h 41m in
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward Multi Purpose Center, Hattiesburg
Fuel & Cost
Regular Gas
$55.26 one way
$110.52 round trip
$3.84/gal25.4 MPG avg128 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$60.66
$121.32
premium
$4.56
$65.67
$131.35
diesel
$5.61
$80.79
$161.57
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$55
Meals
$25–$50
Total
$80–$105
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 128 kg one way.
Prices: EIA weekly data, 2026-04-13.
EV Charging Along Route
40 DC fast chargers
· Coverage: excellent
North Bus Barn
Jackson, MS
NOODOE
14 DCFC
Target - Tesla Supercharger
Horn Lake, MS
Tesla
12 DCFC
South Bus Barn
Jackson, MS
NOODOE
12 DCFC
Lakeview Village Shopping Mall - Tesla Supercharger
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $38 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
109.8
1
$38.42
$17.56
Efficient EV
91.5
1
$32.02
$14.64
EV Truck/SUV
146.4
1
$51.23
$23.42
Gas CO2
128 kg
EV CO2
43 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 14, 2026
Origin
Walls, MS
Evening
in Walls on Saturday
Local time
8:26 PM
CDT
Current temp
50°F
Unavailable
Live forecast
Destination
Biloxi, MS
Evening
in Biloxi on Saturday
Local time
8:26 PM
CDT
Current temp
61°F
Unavailable
Live forecast
55°F
Florence, MS
183 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
11 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
7h 4m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
4 mi from route
~10 min detour
Free
near mile 201.9
Emmett Till and Mamie Till-Mobley National Monument
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
28 mi from route
~71 min detour
Free
near mile 75.7
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a predominantly highway-focused experience, with 94% of your travel on major routes like I-55 and US 49. The longest uninterrupted stretch you'll encounter is 193.5 miles on I-55, so be prepared for extended periods of consistent driving. While much of the route is straightforward interstate travel, you'll transition to US 49 South, which may offer a slightly different feel as you progress southward. This isn't a winding, scenic byway, but rather a direct path designed for covering distance.
94% highway — fuel and pacing are the main things to plan.
28 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 193.5 mi on I 55.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on I 55 and Highway 49 South. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near East Railroad Avenue.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 20 significant decision points across 365.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (East Railroad Avenue): Complex interchange - multiple decisions in a short stretch; at 286.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 294.5 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Walls, MS and Biloxi, MS, road signs point toward Hattiesburg, Richland, Gulf Coast, Mississippi Gulf Coast, Mobile and Gulfport - among others.
Hattiesburg
203 mi in|~3h 45m
Richland
203.9 mi in|~3h 46m|via US 49
Gulf Coast
286.4 mi in|~5h 27m
Mississippi Gulf Coast
286.8 mi in|~5h 28m|via I 59
Mobile
294.5 mi in|~5h 36m|via US 98
Gulfport
297.7 mi in|~5h 40m
Multi Purpose Center
298 mi in|~5h 41m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 7h 4m. Total distance: 365.9 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 4m drive, plan rest stops for pacing.
Frequently Asked Questions
The longest stretch is about 193.5 miles on I 55. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Biloxi, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.1 miles (East Railroad Avenue): Complex interchange - multiple decisions in a short stretch; at 286.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 294.5 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Medgar and Myrlie Evers Home National Monument and Emmett Till and Mamie Till-Mobley National Monument. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 7.1 hours each way, a round trip means 14.2 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Biloxi, MS before the return drive.
