This 335.5-mile journey from New Albany, MS, to Biloxi, MS, is designed for a single day of driving, estimating a total travel time of about 5 hours and 6 minutes. You'll navigate primarily on local roads, specifically mentioning North Railroad Avenue and West Bankhead Street, before transitioning to Highway 15. With a fuel cost estimated at $51, this route offers a straightforward drive through Mississippi's Southeast region. The 'turn-heavy local drive' profile suggests you'll be actively engaged with the road, making it a dynamic experience rather than a passive interstate cruise. Consider this a manageable day trip, perfect for a focused drive.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
166.8 miles from New Albany, MS
A natural place for your longest stop of the day
, about 3h 17m into the drive
.
Main Roads
Road
Distance
Duration
I 59
88.7 mi
1h 36m
US Highway 45 Aiternate
60.6 mi
1h 9m
US Highway 45 Alternate
54.7 mi
1h 6m
US 49
41.9 mi
49m
I 22
21.8 mi
23m
Biloxi-D'Iberville Scenic Expressway
20.5 mi
24m
US 45
18 mi
21m
I 20
8.1 mi
9m
Longest stretch:
I 59
— 88.7 mi, about 1h 36m
Traffic on I-59
Hour-of-day weekday pattern from 12 FHWA count stations on your route.
Peak
4 PM
~976 veh/hr typical
· worst 1,182
Quietest
2 AM
~88 veh/hr
Peak-to-quiet ratio
11.1×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between New Albany, MS and Biloxi, MS.
1
Start on Highland Street
96 ft·9 sec·Highland Street
2
Turn left onto North Railroad Avenue
210 ft·15 sec·North Railroad Avenue
3
Turn left onto MS 178
1.0 mi·2 min·West Bankhead Street
4
Turn right onto MS 15; MS 30
1.0 mi·1 min·Mississippi Highway 15
Use the straight / right lanes.
5
Take the ramp
0.2 mi·28 sec
Toward I-22 East, US 78 East: TupeloUse the left lane.
6
Merge onto I 22; US 78
22 mi·23 min·I 22; US 78
7
Take the exit
0.4 mi·1 min
Toward US 45:south: Tupelo
8
Merge onto US 45
14 mi·17 min·US 45
Use the straight / slight right lanes.
9
Continue on US 45 ALT
1.4 mi·1 min·US 45 ALT
10
Continue on US 45 ALT
2.2 mi·2 min·US 45 ALT
11
Continue on US 45 ALT
1.5 mi·1 min·US 45 ALT
12
Continue on US 45 ALT
0.7 mi·49 sec·US 45 ALT
13
Continue on US 45 ALT
1.4 mi·1 min·US 45 ALT
14
Continue on US 45 ALT
55 mi·1 hr 6 min·US Highway 45 Alternate
Use the straight lane.
15
Continue on US 45
61 mi·1 hr 9 min·US Highway 45 Aiternate
16
Keep slight right at fork onto US 45
3.9 mi·4 min·US 45
17
Take the exit
0.5 mi·1 min
Toward I 59 South, I 20 West: Meridian
18
Merge onto I 20; I 59
6.3 mi·7 min·I 20; I 59
Use the straight / slight right lanes.
19
Continue on I 20; I 59; US 80
1.8 mi·2 min·I 20; I 59; US 80
Use the straight lane.
20
Keep slight left at fork onto I 59
89 mi·1 hr 36 min·I 59
Toward I 59 South: Laurel, New OrleansUse the slight left / slight right lanes.
21
Take the exit onto US 98
3.2 mi·4 min·US 98
Toward US 98 East: Lucedale, MobileUse the straight / slight right lanes.
22
Take the exit
0.3 mi·44 sec
Toward US 49: Wiggins, Gulfport, Mississippi Gulf CoastUse the straight / slight right lanes.
23
Keep slight left at fork
0.2 mi·27 sec
Toward Multi Purpose Center, HattiesburgUse the slight left / slight right lanes.
24
Turn right onto US 49
42 mi·49 min·US 49
Use the straight lane.
25
Take the exit
0.8 mi·1 min
Toward MS 67 South: D'Iberville, Biloxi
26
Continue on MS 67
20 mi·24 min·Biloxi-D'Iberville Scenic Expressway
27
Continue on I 110
3.2 mi·4 min·I 110
28
Take the exit
0.4 mi·47 sec
Exit 1cToward Division Street
29
Turn left onto Division Street
0.6 mi·1 min·Division Street
30
Turn right onto Main Street
0.5 mi·1 min·Main Street
31
Turn left onto Howard Avenue
91 ft·3 sec·Howard Avenue
32
Arrive at destination
Howard Avenue
Trip Plan
Given the 5-hour, 6-minute estimated duration for this 335.5-mile drive, starting your trip in New Albany, MS, in the early morning is advisable to maximize daylight and allow ample time for any brief stops. With only one recommended stop and a fuel cost of approximately $51, this route is well-suited for a single-day excursion. Pay close attention to local road signage as you transition from North Railroad Avenue and West Bankhead Street onto Highway 15. The 'turn-heavy' nature of this drive means staying alert for frequent turns will be key to a smooth journey to Biloxi, MS.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 166.8 miles from New Albany, MS, or about 3h 17m into the drive.
The longest continuous stretch on this route runs about 88.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 73 miles or 1h 27m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 166.8 miles or 3h 17m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 15m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving New Albany, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from New Albany, MS
This is one driving day of about 333.6 miles and 6h 29m.
Your first comfortable stop window is around 73 miles from New Albany, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 59 for about 88.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 19
5 decision points cluster between mile 2 and 265.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
2 mi into trip|~4m in
Take the ramp toward I-22 East, US 78 East: Tupelo
Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Toward I-22 East, US 78 East: Tupelo
8
173.6 mi into trip|~3h 25m in|I 59
Keep slight left at fork onto I 59 toward I 59 South: Laurel, New Orleans
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward I 59 South: Laurel, New Orleans
7
262.3 mi into trip|~5h 1m in|US 98
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 98 East: Lucedale, Mobile
7
265.5 mi into trip|~5h 5m in
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 49: Wiggins, Gulfport, Mississippi Gu...
9
265.8 mi into trip|~5h 6m in
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward Multi Purpose Center, Hattiesburg
Fuel & Cost
Regular Gas
$46.31 one way
$92.62 round trip
$3.53/gal25.4 MPG avg117 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$3.95
$51.81
$103.63
premium
$4.29
$56.33
$112.66
diesel
$4.80
$62.99
$125.98
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$46
Meals
$25–$50
Total
$71–$96
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 116.7 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $35 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
100.1
1
$35.03
$16.01
Efficient EV
83.4
0
$29.19
$13.34
EV Truck/SUV
133.4
1
$46.70
$21.35
Gas CO2
117 kg
EV CO2
39 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 17, 2026
Origin
New Albany, MS
Night
in New Albany on Saturday
Local time
9:52 PM
CDT
Current temp
93°F
Sunny
WNW 5 to 10 mph12% chanceLive forecast
Destination
Biloxi, MS
Night
in Biloxi on Saturday
Local time
9:52 PM
CDT
Current temp
95°F
Mostly Sunny
W 5 to 10 mph7% chanceLive forecast
95°F
Meridian, MS
167 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 29m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Natchez Trace National Scenic Trail
National Scenic Trail
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
2 mi from route
~6 min detour
Free
near mile 23
Park Closure: Partial Closure of Rocky Springs Trail
Park Closure: Temporary Blackland Prairie Trail Closure to Equestrians
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a 'turn-heavy local drive' for the majority of this 335.5-mile trip, with no highway segments contributing to the total mileage. This means you'll be encountering more intersections and changes in direction, keeping you engaged behind the wheel. While the longest uninterrupted stretch isn't specified, the emphasis on local roads and Highway 15 suggests a route that winds through communities rather than bypassing them. The absence of highway driving means a potentially slower pace but also a more intimate connection with the landscape as you travel.
99% highway — fuel and pacing are the main things to plan.
32 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 88.7 mi on I 59.
How Hard Is This Drive?
10/10
This is a straightforward highway drive that stays mostly on I 59 and US Highway 45 Aiternate. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 2 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 19 significant decision points across 333.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 2 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 173.6 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 262.3 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
394 ft20 ft
Total Climb
290 ft
Total Descent
631 ft
Highest Point
394 ft
~166.8 mi in
Elevation Range
374 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between New Albany, MS and Biloxi, MS, road signs point toward New Orleans, Mobile, Gulfport, Mississippi Gulf Coast, Multi Purpose Center and Hattiesburg.
Biloxi is a city in Harrison County, on the Gulf Coast of Mississippi. It's well known for its beaches and nine casinos. It is also home to the "Jefferson Davis Presidential Library and Museum", which serves as a museum of the Confederacy.
Top landmarks
•Jefferson Davis Presidential Library and Museum — presidential library and museum for Confederate States President Jefferson Davis...
•Beauvoir — post-war home of the former President of the Confederate States of America, Jeff...
•Biloxi Light — lighthouse in Mississippi, United States
Doable as a same-day drive at 6h 29m. Total distance: 333.6 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 29m drive, plan rest stops for pacing.
Frequently Asked Questions
The longest stretch is about 88.7 miles on I 59. The full list of main roads is in the Roads section above.
Yes — we found about 12 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Biloxi, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 12 rest areas along the route for bathroom stops.
The main spots that need attention: at 2 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 173.6 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 262.3 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Natchez Trace National Scenic Trail and Tupelo National Battlefield. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 6.5 hours each way, a round trip means 13.0 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Biloxi, MS before the return drive.
