If you are looking to head south from Petal to the coast in Biloxi, you are looking at a straightforward 76.4-mile journey. Expect to spend about 1 hour and 40 minutes on the road, making this a perfect candidate for a single-day trip. You will primarily utilize US 49, the Biloxi-D'Iberville Scenic Expressway, and I-110 to complete the transit. With fuel costs estimated at $12, it is a budget-friendly way to move between these two Southeast Mississippi locations. Since the entire drive stays within the same region, you won't experience drastic climate or geographic shifts, allowing for a comfortable and predictable travel experience. Whether you are aiming for a quick beach getaway or a day of coastal exploration, this route is efficient enough to get you there without requiring an overnight stay.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
38.2 miles from Petal, MS
A natural place for your longest stop of the day
, about 52m into the drive
.
Main Roads
Road
Distance
Duration
US 49
44.4 mi
52m
Biloxi-D'Iberville Scenic Expressway
20.5 mi
24m
I 110
3.2 mi
4m
Edwards Street
2.8 mi
6m
South Main Street
1.2 mi
2m
River Avenue
0.7 mi
1m
Division Street
0.6 mi
1m
Hall Avenue
0.6 mi
1m
Longest stretch:
US 49
— 44.4 mi, about 52m
Turn-by-Turn Driving Directions
Step-by-step road directions between Petal, MS and Biloxi, MS.
1
Start on Morris Street
0.3 mi·47 sec·Morris Street
2
Turn left onto South Main Street
1.2 mi·2 min·South Main Street
3
Continue on River Avenue
0.7 mi·1 min·River Avenue
4
Turn left onto Gulfport Street
0.5 mi·1 min·Gulfport Street
5
Continue on Hall Avenue
0.6 mi·1 min·Hall Avenue
6
Enter roundabout onto James Street
224 ft·4 sec·James Street
7
Continue on James Street
476 ft·13 sec·James Street
8
Turn right onto Edwards Street
2.8 mi·6 min·Edwards Street
Use the right lane.
9
Turn left onto US 49
0.3 mi·27 sec·US 49
Use the left / straight / right lanes.
10
Continue on US 49
2.1 mi·2 min·US 49
Use the straight lane.
11
Turn straight onto US 49
42 mi·49 min·US 49
Use the straight lane.
12
Take the exit
0.8 mi·1 min
Toward MS 67 South: D'Iberville, Biloxi
13
Continue on MS 67
20 mi·24 min·Biloxi-D'Iberville Scenic Expressway
14
Continue on I 110
3.2 mi·4 min·I 110
15
Take the exit
0.4 mi·47 sec
Exit 1cToward Division Street
16
Turn left onto Division Street
0.6 mi·1 min·Division Street
17
Turn right onto Main Street
0.5 mi·1 min·Main Street
18
Turn left onto Howard Avenue
91 ft·3 sec·Howard Avenue
19
Arrive at destination
Howard Avenue
Trip Plan
Since this is a relatively short trip, you have the flexibility to depart whenever fits your schedule best, though avoiding peak traffic hours near the coast is always a smart move. Because there are no mandatory stops scheduled, you can easily handle the 1 hour and 40 minutes of driving in one go without needing to plan for lengthy rest breaks. Keep your fuel budget around $12 in mind, and consider topping off your tank before you leave Petal to ensure you aren't searching for stations on the highway. A practical tip for this specific route is to monitor your speed closely as you transition from US 49 onto the expressway, as traffic patterns often change quickly when entering the more densely populated Biloxi-D'Iberville area.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 38.2 miles from Petal, MS, or about 52m into the drive.
The longest continuous stretch on this route runs about 44.4 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 17 miles or 27m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 38.2 miles or 52m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 23m
Traffic, exits, and arrival timing usually matter more near Biloxi, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Petal, MS so your first major turns are already loaded.
Day 1
Settle into the route from Petal, MS
This is one driving day of about 76.4 miles and 1h 40m.
Your first comfortable stop window is around 17 miles from Petal, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 49 for about 44.4 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 0.3 and 74.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0.3 mi into trip|~0m in|South Main Street
Turn left onto South Main Street
Navigation decision point
4
2.1 mi into trip|~4m in|Gulfport Street
Turn left onto Gulfport Street
Navigation decision point
5
3.3 mi into trip|~8m in|Edwards Street
Turn right onto Edwards Street
Lane positioning matters here
Use the right lane.
5
50.6 mi into trip|~1h 6m in
Take the exit toward MS 67 South: D'Iberville, Biloxi
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward MS 67 South: D'Iberville, Biloxi
5
74.9 mi into trip|~1h 36m in
Take the exit toward Division Street
Exit ramp - move to the correct lane early
Exit 1c
Toward Division Street
Fuel & Cost
Regular Gas
$11.54 one way
$23.08 round trip
$3.84/gal25.4 MPG avg27 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$12.67
$25.33
premium
$4.56
$13.71
$27.43
diesel
$5.61
$16.87
$33.74
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$12
Meals
$25–$50
Total
$37–$62
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 26.7 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $8 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
22.9
0
$8.02
$3.67
Efficient EV
19.1
0
$6.69
$3.06
EV Truck/SUV
30.6
0
$10.70
$4.89
Gas CO2
27 kg
EV CO2
9 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 14, 2026
Origin
Petal, MS
Late night
in Petal on Tuesday
Local time
3:46 AM
CDT
Current temp
86°F
Unavailable
Live forecast
Destination
Biloxi, MS
Late night
in Biloxi on Tuesday
Local time
3:46 AM
CDT
Current temp
65°F
Mostly Clear
SE 5 mph0% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
21 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 40m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive is a highway-focused experience, with 89% of your time spent on high-speed thoroughfares. You will face a longest uninterrupted stretch of 44.4 miles while navigating US 49, which defines the bulk of your travel time. The road maintains a consistent pace, shifting from open highway stretches into the more structured Biloxi-D'Iberville Scenic Expressway as you approach the coast. Because the route relies heavily on major arteries, you should anticipate a steady, utilitarian drive rather than a winding backroads adventure. Staying alert is key during those long miles on US 49, where the road conditions remain fairly uniform until you reach the final approach into the Biloxi area.
89% highway — fuel and pacing are the main things to plan.
19 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 44.4 mi on US 49.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on US 49 and Biloxi-D'Iberville Scenic Expressway. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.3 miles in near South Main Street.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 40m drive. You will face about 10 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 0.3 miles (South Main Street): Navigation decision point; at 2.1 miles (Gulfport Street): Navigation decision point; at 3.3 miles (Edwards Street): Lane positioning matters here.
Detours Along the Way
Tagged by where each one fits in your drive — first break, midpoint, final stretch.
Biloxi is a city in Harrison County, on the Gulf Coast of Mississippi. It's well known for its beaches and nine casinos. It is also home to the "Jefferson Davis Presidential Library and Museum", which serves as a museum of the Confederacy.
The longest stretch is about 44.4 miles on US 49. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 0.3 miles (South Main Street): Navigation decision point; at 2.1 miles (Gulfport Street): Navigation decision point; at 3.3 miles (Edwards Street): Lane positioning matters here.
Yes. A round trip is manageable in a single day if you plan a break at Biloxi, MS before heading back.
