Newton, MS to City of Greenville, MS is 183.6 miles and takes about 3h 43m via I 20 and US 49W, with a fuel budget near $28 and enough daylight to finish in a day. This trip stays within Mississippi, moving from the Southeast region to another part of the Southeast. Expect a drive that's predominantly on highways, making it a straightforward journey. With a recommended one day for travel, you'll likely find this route efficient for getting from point A to point B without extensive planning.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
91.8 miles from Newton, MS
A natural place for your longest stop of the day
, about 1h 48m into the drive
.
Main Roads
Road
Distance
Duration
I 20
58.2 mi
1h 3m
US 49W
46.7 mi
56m
Medgar Evers Boulevard
39.5 mi
48m
US 82
15.8 mi
19m
MS 182
8.3 mi
12m
US 80
6.2 mi
9m
US 49
5.5 mi
6m
West Church Street
1.4 mi
3m
Longest stretch:
I 20
— 58.2 mi, about 1h 3m
Turn-by-Turn Driving Directions
Step-by-step road directions between Newton, MS and City of Greenville, MS.
1
Start on South Main Street
187 ft·12 sec·South Main Street
2
Turn left onto West Church Street
1.4 mi·3 min·West Church Street
3
Continue on West Church Street
235 ft·6 sec·West Church Street
4
Turn straight onto US 80
6.2 mi·9 min·US 80
5
Take the ramp
0.2 mi·28 sec
6
Merge onto I 20
54 mi·58 min·I 20
7
Merge onto I 20; I 55; US 49
1.6 mi·2 min·I 20; I 55; US 49
8
Keep slight right at fork onto I 20; US 49
2.7 mi·3 min·I 20; US 49
Toward I 20 West, US 49 North: Vicksburg, Yazoo City
9
Take the exit onto US 49
5.2 mi·6 min·US 49
Toward I 220 North, I 49 North: North Jackson, Yazoo City
10
Take the exit onto US 49
0.3 mi·33 sec·US 49
Toward US 49 North: Yazoo City
11
Merge onto US 49
39 mi·48 min·Medgar Evers Boulevard
12
Take the exit onto US 49W
47 mi·56 min·US 49W
Toward US 49W North, MS 3 South: Indianola, Vicksburg
13
Turn left onto US 82
2.4 mi·3 min·US 82
14
Keep slight left at fork onto US 82
0.4 mi·29 sec·US 82
15
Keep slight left at fork onto US 82
13 mi·15 min·US 82
16
Turn right onto MS 182
8.3 mi·12 min·MS 182
17
Turn left onto MS 1
1.0 mi·1 min·Martin Luther King Junior Boulevard
18
Turn right onto East Reed Road
0.7 mi·1 min·East Reed Road
19
Turn left onto Sandy Avenue
46 ft·2 sec·Sandy Avenue
20
Arrive at destination
Sandy Avenue
Trip Plan
Given the 3h 43m estimated duration, departing in the morning from Newton, MS, will give you ample time to reach Greenville, MS, well before evening. The drive is designed for a single day, so you can be flexible with your departure time. Plan for one stop along the way, which should be sufficient for a break and to refuel if needed, especially since the longest stretch without a change in major road is 58.2 miles. Keep an eye on your fuel gauge as you approach Greenville, as services can sometimes be more spread out between major highway exits.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 91.8 miles from Newton, MS, or about 1h 48m into the drive.
The longest continuous stretch on this route runs about 58.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 40 miles or 48m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 91.8 miles or 1h 48m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h
Traffic, exits, and arrival timing usually matter more near City of Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Newton, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Newton, MS
This is one driving day of about 183.6 miles and 3h 43m.
Your first comfortable stop window is around 40 miles from Newton, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 20 for about 58.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 14
5 decision points cluster between mile 63.3 and 160.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
63.3 mi into trip|~1h 13m in|I 20; US 49
Keep slight right at fork onto I 20; US 49 toward I 20 West, US 49 North: Vicksburg, Yazoo City
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
5
66 mi into trip|~1h 17m in|US 49
Take the exit onto US 49 toward I 220 North, I 49 North: North Jackson, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward I 220 North, I 49 North: North Jackson,...
4
71.2 mi into trip|~1h 23m in|US 49
Take the exit onto US 49 toward US 49 North: Yazoo City
Exit ramp - move to the correct lane early
Toward US 49 North: Yazoo City
5
111 mi into trip|~2h 12m in|US 49W
Take the exit onto US 49W toward US 49W North, MS 3 South: Indianola, Vicksburg
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 49W North, MS 3 South: Indianola, Vic...
4
160.1 mi into trip|~3h 12m in|US 82
Keep slight left at fork onto US 82
Highway fork - watch signs carefully
Fuel & Cost
Regular Gas
$27.73 one way
$55.46 round trip
$3.84/gal25.4 MPG avg64 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$30.44
$60.88
premium
$4.56
$32.95
$65.91
diesel
$5.61
$40.54
$81.07
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$28
Meals
$25–$50
Total
$53–$78
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 64.2 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $19 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
55.1
0
$19.28
$8.81
Efficient EV
45.9
0
$16.06
$7.34
EV Truck/SUV
73.4
0
$25.70
$11.75
Gas CO2
64 kg
EV CO2
21 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Newton, MS
Morning
in Newton on Sunday
Local time
7:10 AM
CDT
Current temp
79°F
Unavailable
Live forecast
Destination
City of Greenville, MS
Morning
in City of Greenville on Sunday
Local time
7:10 AM
CDT
Current temp
80°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 43m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route is primarily a highway-focused drive, with 77% of the journey on major roadways. You'll experience a significant stretch of 58.2 miles on I 20, offering a consistent pace. As you transition to US 49W and then Medgar Evers Boulevard, the character may shift slightly, but the overall feel remains geared towards efficient travel rather than a winding scenic tour. Expect a largely uninterrupted driving experience on the main highway segments.
77% highway — fuel and pacing are the main things to plan.
20 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 58.2 mi on I 20.
How Hard Is This Drive?
7/10
This is a straightforward highway drive that stays mostly on I 20 and US 49W. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 63.3 miles in near I 20; US 49.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 183.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 63.3 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 66 miles (US 49): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 71.2 miles (US 49): Exit ramp - move to the correct lane early.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Newton, MS and City of Greenville, MS, road signs point toward Yazoo City and Vicksburg.
Yazoo City
63.3 mi in|~1h 13m|via I 20; US 49
Vicksburg
111 mi in|~2h 12m|via US 49W
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 43m. Total distance: 183.6 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 43m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (77%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 58.2 miles on I 20. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at City of Greenville, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 63.3 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 66 miles (US 49): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 71.2 miles (US 49): Exit ramp - move to the correct lane early.
Yes — Medgar and Myrlie Evers Home National Monument. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.7 hours each way, an in-and-out day trip would put you behind the wheel for 7.5 hours — manageable with a long break at City of Greenville, MS, but most travelers stay overnight.
