Traveling from Greenville to Byram covers 127.2 miles through the heart of Mississippi. Expect a total drive time of approximately 2 hours and 39 minutes, making this an ideal one-day excursion. You will primarily navigate via North Martin Luther King Drive, Jerry Clower Boulevard, and US 82. With an estimated fuel cost of $19, the trip is quite budget-friendly for a solo driver or a small group. Since both cities are located within the Southeast region, the environment remains consistent throughout your journey. This route is straightforward enough that you won't need to worry about overnight logistics, allowing you to complete the transit comfortably in a single afternoon.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
63.6 miles from City of Greenville, MS
A natural place for your longest stop of the day
, about 1h 20m into the drive
.
Main Roads
Road
Distance
Duration
North Martin Luther King Drive
46.2 mi
55m
Jerry Clower Boulevard
38.8 mi
47m
US 82
15.8 mi
19m
MS 182
8.3 mi
12m
US 49
7.4 mi
9m
I 55
6.6 mi
7m
Martin Luther King Junior Boulevard
1 mi
1m
South Siwell Road
0.8 mi
1m
Longest stretch:
North Martin Luther King Drive
— 46.2 mi, about 55m
Turn-by-Turn Driving Directions
Step-by-step road directions between City of Greenville, MS and Byram, MS.
1
Start on Sandy Avenue
46 ft·3 sec·Sandy Avenue
2
Turn right onto East Reed Road
0.7 mi·1 min·East Reed Road
3
Turn left onto MS 1
1.0 mi·1 min·Martin Luther King Junior Boulevard
4
Continue on MS 182
8.3 mi·12 min·MS 182
5
Turn left onto US 82; US 278
16 mi·19 min·US 82; US 278
Use the straight lane.
6
Turn right onto US 49W
46 mi·55 min·North Martin Luther King Drive
7
Keep slight right at fork onto US 49W
0.5 mi·53 sec·US 49W
Toward US 49 South: Jackson
8
Merge onto US 49
39 mi·47 min·Jerry Clower Boulevard
9
Take the exit onto US 49
4.9 mi·5 min·US 49
10
Keep slight left at fork onto US 49
2.5 mi·3 min·US 49
11
Take the exit
302 ft·7 sec
Exit 43A-BToward I 55 South
12
Keep slight left at fork
0.2 mi·31 sec
Toward I 55 South
13
Keep slight left at fork
0.5 mi·1 min
Toward I 55 South
14
Merge onto I 55; US 51
6.6 mi·7 min·I 55; US 51
15
Take the exit
0.3 mi·42 sec
Toward Byram
16
Turn left onto South Siwell Road
0.8 mi·1 min·South Siwell Road
17
Arrive at destination
South Siwell Road
Trip Plan
Planning for a single stop during your 2-hour and 39-minute drive will help you break up the 127.2-mile stretch effectively. Since the fuel cost is a modest $19, you have plenty of flexibility to fill up whenever it is most convenient for your schedule. Aim to depart mid-morning to avoid potential commuter traffic and ensure you have plenty of daylight for the transit. Because the route relies on a mix of local roads and highways like US 82, pay close attention to signage when transitioning between these different road types. Keeping your pace consistent on the 46.2-mile stretch of North Martin Luther King Drive is the best way to maintain a smooth flow for the duration of the trip.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 63.6 miles from City of Greenville, MS, or about 1h 20m into the drive.
The longest continuous stretch on this route runs about 46.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 28 miles or 37m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 63.6 miles or 1h 20m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 10m
Traffic, exits, and arrival timing usually matter more near Byram, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving City of Greenville, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from City of Greenville, MS
This is one driving day of about 127.2 miles and 2h 39m.
Your first comfortable stop window is around 28 miles from City of Greenville, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on North Martin Luther King Drive for about 46.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 12
5 decision points cluster between mile 10 and 119 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
10 mi into trip|~15m in|US 82; US 278
Turn left onto US 82; US 278
Lane positioning matters here
Use the straight lane.
5
72 mi into trip|~1h 30m in|US 49W
Keep slight right at fork onto US 49W toward US 49 South: Jackson
Highway fork - watch signs carefully
Toward US 49 South: Jackson
5
118.7 mi into trip|~2h 28m in
Take the exit toward I 55 South
Exit ramp - move to the correct lane early
Exit 43A-B
Toward I 55 South
6
118.8 mi into trip|~2h 28m in
Keep slight left at fork toward I 55 South
Highway fork - watch signs carefully
Toward I 55 South
5
119 mi into trip|~2h 28m in
Keep slight left at fork toward I 55 South
Highway fork - watch signs carefully
Toward I 55 South
Fuel & Cost
Regular Gas
$19.21 one way
$38.42 round trip
$3.84/gal25.4 MPG avg45 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$21.09
$42.18
premium
$4.56
$22.83
$45.66
diesel
$5.61
$28.08
$56.17
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$19
Meals
$25–$50
Total
$44–$69
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 44.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $13 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
38.2
0
$13.36
$6.11
Efficient EV
31.8
0
$11.13
$5.09
EV Truck/SUV
50.9
0
$17.81
$8.14
Gas CO2
45 kg
EV CO2
15 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
City of Greenville, MS
Night
in City of Greenville on Saturday
Local time
11:50 PM
CDT
Current temp
80°F
Unavailable
Live forecast
Destination
Byram, MS
Night
in Byram on Saturday
Local time
11:50 PM
CDT
Current temp
55°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
25 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 39m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This 127.2-mile journey offers a mixed driving profile that keeps the experience varied. You will spend roughly 30% of your time on highways, balancing faster stretches with local road navigation. The longest uninterrupted portion of the drive spans 46.2 miles along North Martin Luther King Drive, providing a steady rhythm before the road transitions. Because the drive is a blend of different road types, you should stay alert as the pace shifts between urban and rural segments. It is not a monotonous interstate grind, but rather a practical connection that requires you to adapt to changing traffic patterns as you move toward your destination.
30% highway, the rest on surface roads — varied driving throughout.
17 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 46.2 mi on North Martin Luther King Drive.
How Hard Is This Drive?
8/10
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 10 miles in near US 82; US 278.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 12 significant decision points across 127.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 10 miles (US 82; US 278): Lane positioning matters here; at 72 miles (US 49W): Highway fork - watch signs carefully; at 118.7 miles: Exit ramp - move to the correct lane early.
Elevation Profile
Mostly flat terrain
367 ft106 ft
Total Climb
467 ft
Total Descent
330 ft
Highest Point
367 ft
~116.6 mi in
Elevation Range
261 ft
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 39m. Total distance: 127.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
2h 39m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (30%). Some complex stretches to watch for.
Scenic Drive
Mixed highway & surface route profile.
Frequently Asked Questions
The longest stretch is about 46.2 miles on North Martin Luther King Drive. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Byram, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 10 miles (US 82; US 278): Lane positioning matters here; at 72 miles (US 49W): Highway fork - watch signs carefully; at 118.7 miles: Exit ramp - move to the correct lane early.
Yes. A round trip is manageable in a single day if you plan a break at Byram, MS before heading back.
