Spanning 171 miles across Mississippi, this drive connects New Albany to Greenville in approximately 3 hours and 50 minutes. It is a straightforward, highway-focused journey that is easily manageable as a one-day trip. You should budget about $26 for fuel to complete the trek. Since both cities are located within the Southeast, the drive offers a consistent regional feel as you head west. Whether you are traveling for business or a change of scenery, the route is efficient and requires minimal logistical planning.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
85.5 miles from New Albany, MS
A natural place for your longest stop of the day
, about 2h into the drive
.
Main Roads
Road
Distance
Duration
US 278
125.3 mi
2h 39m
MS 30
30.1 mi
44m
MS 182
8.7 mi
12m
MS 7
1.8 mi
2m
North Broad Street
1.4 mi
2m
West Bankhead Street
1.1 mi
2m
South Main Street
0.9 mi
2m
Old Hwy 61
0.8 mi
1m
Longest stretch:
US 278
— 125.3 mi, about 2h 39m
Turn-by-Turn Driving Directions
Step-by-step road directions between New Albany, MS and Greenville, MS.
1
Start on Highland Street
96 ft·9 sec·Highland Street
2
Turn left onto North Railroad Avenue
210 ft·13 sec·North Railroad Avenue
3
Turn right onto MS 178
1.1 mi·2 min·West Bankhead Street
Use the straight lane.
4
Turn left onto Highway 30 West
0.4 mi·43 sec·Highway 30 West
Use the left lane.
5
Continue on MS 30
30 mi·44 min·MS 30
6
Take the ramp onto MS 30
143 ft·11 sec·Mississippi Highway 30
7
Take the ramp
0.2 mi·31 sec
8
Merge onto MS 7
1.8 mi·2 min·MS 7
9
Take the exit
0.3 mi·39 sec
10
Merge onto US 278; MS 6
60 mi·1 hr 20 min·US 278; MS 6
11
Take the exit onto US 278
65 mi·1 hr 19 min·US 278
12
Turn right onto Griffin Road
145 ft·7 sec·Griffin Road
13
Turn left onto Old Hwy 61
0.8 mi·1 min·Old Hwy 61
14
Turn straight onto North Broad Street
1.4 mi·2 min·North Broad Street
15
Turn right onto MS 182
8.7 mi·12 min·MS 182
16
Turn right onto South Main Street
0.9 mi·2 min·South Main Street
17
Turn right onto MS 814
10 ft·0 sec·South Broadway Street
18
Arrive at destination
MS 814
Trip Plan
To keep your trip efficient, plan for at least one dedicated stop during your 171-mile transit to stretch your legs. Given the duration, leaving in the morning allows you to arrive in Greenville with plenty of daylight to spare. Since the drive is heavily highway-oriented, keep a steady eye on your fuel gauge, though $26 should cover your requirements for the trip. Use the flexibility of a one-day schedule to decide whether you want to power through the 125.3-mile stretch on US 278 or break it up early to avoid fatigue.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 85.5 miles from New Albany, MS, or about 2h into the drive.
The longest continuous stretch on this route runs about 125.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 38 miles or 57m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 85.5 miles or 2h in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 8m
Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving New Albany, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from New Albany, MS
This is one driving day of about 171 miles and 3h 50m.
Your first comfortable stop window is around 38 miles from New Albany, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 278 for about 125.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 14
5 decision points cluster between mile 0 and 170.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0 mi into trip|~0m in|North Railroad Avenue
Turn left onto North Railroad Avenue
Navigation decision point
6
0.1 mi into trip|~0m in|MS 178 / West Bankhead Street
Turn right onto MS 178 / West Bankhead Street
Lane positioning matters here
Use the straight lane.
5
1.1 mi into trip|~2m in|Highway 30 West
Turn left onto Highway 30 West
Lane positioning matters here
Use the left lane.
4
159.3 mi into trip|~3h 31m in|Griffin Road
Turn right onto Griffin Road
Navigation decision point
4
170.2 mi into trip|~3h 48m in|South Main Street
Turn right onto South Main Street
Navigation decision point
Fuel & Cost
Regular Gas
$25.83 one way
$51.65 round trip
$3.84/gal25.4 MPG avg60 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$28.35
$56.70
premium
$4.56
$30.69
$61.38
diesel
$5.61
$37.75
$75.51
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$26
Meals
$25–$50
Total
$51–$76
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 59.8 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $18 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
51.3
0
$17.96
$8.21
Efficient EV
42.8
0
$14.96
$6.84
EV Truck/SUV
68.4
0
$23.94
$10.94
Gas CO2
60 kg
EV CO2
20 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
New Albany, MS
Late night
in New Albany on Sunday
Local time
3:00 AM
CDT
Current temp
77°F
Unavailable
Live forecast
Destination
Greenville, MS
Late night
in Greenville on Sunday
Local time
3:00 AM
CDT
Current temp
77°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
Very similar conditions
Both ends of the route are sitting at about the same temperature right now.
Road read
3h 50m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Emmett Till and Mamie Till-Mobley National Monument
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
18 mi from route
~45 min detour
Free
near mile 88.5
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a focused experience behind the wheel, as 98% of this trip takes place on highways. You will spend the bulk of your time on US 278, which accounts for the longest stretch of 125.3 miles of the journey. The remainder of the route utilizes MS 30 and MS 182 to round out your transit. Because the majority of the drive is highway-based, the pace remains steady and predictable for the duration of the 3-hour and 50-minute travel time.
98% highway — fuel and pacing are the main things to plan.
18 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 125.3 mi on US 278.
How Hard Is This Drive?
3/10
This is a straightforward highway drive that stays mostly on US 278 and MS 30. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near North Railroad Avenue.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 3h 50m drive. You will face about 14 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (North Railroad Avenue): Navigation decision point; at 0.1 miles (MS 178 / West Bankhead Street): Lane positioning matters here; at 1.1 miles (Highway 30 West): Lane positioning matters here.
Greenville is a city in Washington County, Mississippi, United States. The population was 30,000 in 2020, making it the ninth largest city in the state. It is the county seat of Washington County.
The longest stretch is about 125.3 miles on US 278. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: near the start (North Railroad Avenue): Navigation decision point; at 0.1 miles (MS 178 / West Bankhead Street): Lane positioning matters here; at 1.1 miles (Highway 30 West): Lane positioning matters here.
Yes — Emmett Till and Mamie Till-Mobley National Monument, Natchez Trace National Scenic Trail and Tupelo National Battlefield. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.8 hours each way, an in-and-out day trip would put you behind the wheel for 7.7 hours — manageable with a long break at Greenville, MS, but most travelers stay overnight.
