Spanning 158.2 miles across Mississippi, this drive from Carthage to Greenville typically takes about 3 hours and 43 minutes. Since the entire journey stays within the Southeast, you will notice a consistent regional atmosphere as you transition between these two towns. Budgeting approximately $24 for fuel makes this a relatively affordable excursion. Because the trip is manageable in a single day, you can easily complete the drive without needing an overnight stay. It serves as a straightforward, mixed-profile route that balances travel time with the convenience of a one-day itinerary. Planning for a single stop along the way will help keep you refreshed for the duration of the trip.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
79.1 miles from Carthage, MS
A natural place for your longest stop of the day
, about 1h 49m into the drive
.
Main Roads
Road
Distance
Duration
State Route 17
42.1 mi
1h 1m
E. E. Wallace Boulevard North
33 mi
38m
US 65
11.7 mi
16m
Natchez-Vidalia Bridge
10.6 mi
12m
Constitution Avenue
10.2 mi
15m
US 82
8.3 mi
10m
Highway 578
7.7 mi
10m
South Archer Street
7.5 mi
11m
Longest stretch:
State Route 17
— 42.1 mi, about 1h 1m
Turn-by-Turn Driving Directions
Step-by-step road directions between Carthage, MS and Greenville, MS.
1
Start on this road
45 ft·2 sec·this road
2
Turn straight onto Carthage Point Road
2.1 mi·8 min·Carthage Point Road
3
Keep slight left at fork onto Carthage Point Road
0.1 mi·29 sec·Carthage Point Road
4
Turn straight onto Lower Woodville Road
2.2 mi·5 min·Lower Woodville Road
5
Turn left onto US 84; US 425
1.7 mi·2 min·John R Junkin Drive
6
Continue on US 84; US 425
11 mi·12 min·Natchez-Vidalia Bridge
7
Continue on US 425; LA 15
33 mi·38 min·E. E. Wallace Boulevard North
8
Turn right onto LA 128
0.2 mi·17 sec·Lee Street
9
Continue on LA 128
0.9 mi·1 min·Como Road
10
Continue on LA 128
4.0 mi·5 min·Highway 128
11
At end of road, turn left onto LA 4; LA 128
2.4 mi·3 min·Highway 4
12
Turn right onto LA 578
7.7 mi·10 min·Highway 578
13
Turn slight right onto LA 17; LA 577
0.2 mi·15 sec·Highway 577
14
Continue on LA 17
15 mi·22 min·State Route 17
15
Continue on LA 17
1.0 mi·1 min·Broadway Street
16
Continue on LA 17
0.7 mi·1 min·Main Street
17
Continue on LA 17
19 mi·27 min·State Route 17
18
Continue on LA 17
1.0 mi·1 min·Broadway Street
19
Continue on LA 17; LA 588
8.0 mi·11 min·State Route 17
20
Continue on Constitution Avenue
0.5 mi·46 sec·Constitution Avenue
21
Continue on LA 17
0.1 mi·10 sec·Front Street
22
Continue on LA 17
9.7 mi·14 min·Constitution Avenue
23
Continue on Avenue Kilbourne
1.3 mi·1 min·Avenue Kilbourne
24
Continue on AR 159
7.5 mi·11 min·South Archer Street
25
Turn right onto AR 159
342 ft·5 sec·West Lee Street
26
Continue on AR 159
0.3 mi·25 sec·South Main Street
27
Turn right onto AR 8
0.2 mi·27 sec·East Armstrong Street
28
At end of road, turn left onto US 65
12 mi·16 min·US 65
29
Turn right onto US 82; US 278
8.3 mi·10 min·US 82; US 278
30
Take the exit
0.4 mi·58 sec
31
Turn left
0.5 mi·42 sec
32
Continue on MS 182
5.7 mi·7 min·MS 182
33
Turn left onto MS 814
2.0 mi·3 min·South Broadway Street
34
Arrive at destination
MS 814
Trip Plan
To make the most of your 3-hour and 43-minute journey, aim to depart early in the morning to avoid midday traffic fluctuations. Since you are only planning for one stop, look for a convenient location around the midpoint of your 158.2-mile trek to stretch your legs. Keep a close eye on your fuel gauge, especially when transitioning off the main highways, to ensure you stay within your $24 budget. Because the route is compact enough for a single day, you have the flexibility to adjust your pace based on how you feel behind the wheel. A helpful tip for this specific route is to prioritize your fuel stop while you are still on the more populated highway segments to ensure easy access to service stations.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 79.1 miles from Carthage, MS, or about 1h 49m into the drive.
The longest continuous stretch on this route runs about 42.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 35 miles or 49m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 79.1 miles or 1h 49m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 3m
Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Carthage, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Carthage, MS
This is one driving day of about 158.2 miles and 3h 43m.
Your first comfortable stop window is around 35 miles from Carthage, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on State Route 17 for about 42.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 9
5 decision points cluster between mile 2.2 and 129.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
2.2 mi into trip|~8m in|Carthage Point Road
Keep slight left at fork onto Carthage Point Road
Highway fork - watch signs carefully
4
49.7 mi into trip|~1h 6m in|LA 128 / Lee Street
Turn right onto LA 128 / Lee Street
Navigation decision point
4
54.7 mi into trip|~1h 13m in|LA 4; LA 128 / Highway 4
At end of road, turn left onto LA 4; LA 128 / Highway 4
Navigation decision point
5
129.3 mi into trip|~3h 2m in|AR 8 / East Armstrong Street
Turn right onto AR 8 / East Armstrong Street
Navigation decision point
5
129.6 mi into trip|~3h 3m in|US 65
At end of road, turn left onto US 65
Navigation decision point
Fuel & Cost
Regular Gas
$23.89 one way
$47.78 round trip
$3.84/gal25.4 MPG avg55 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$26.23
$52.46
premium
$4.56
$28.40
$56.79
diesel
$5.61
$34.93
$69.86
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$24
Meals
$25–$50
Total
$49–$74
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 55.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $17 in charging
· 0 stops
· 65% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
47.5
0
$16.61
$7.59
Efficient EV
39.6
0
$13.84
$6.33
EV Truck/SUV
63.3
0
$22.15
$10.12
Gas CO2
55 kg
EV CO2
19 kg (65% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Carthage, MS
Morning
in Carthage on Sunday
Local time
9:39 AM
CDT
Current temp
57°F
Unavailable
Live forecast
Destination
Greenville, MS
Morning
in Greenville on Sunday
Local time
9:39 AM
CDT
Current temp
77°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
20 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 43m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Natchez National Historical Park
National Historical Park
Discover the history of all the peoples of Natchez, Mississippi, from European settlement, African enslavement, the American cotton economy, to the Civil Rights struggle on the lower Mississippi River...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a mixed driving experience as you navigate a combination of local roads and highway segments. State Route 17, E. E. Wallace Boulevard North, and US 65 form the backbone of your path, with highways accounting for 52% of the journey. You will encounter a longest uninterrupted stretch of 42.1 miles on State Route 17, which provides a good opportunity to settle into a steady pace. The character of the road shifts as you transition between these different routes, moving from local stretches into more sustained highway driving. Overall, the drive offers a varied environment that keeps the experience from feeling like a monotonous interstate grind.
52% highway, the rest on surface roads — varied driving throughout.
34 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 42.1 mi on State Route 17.
How Hard Is This Drive?
3/10
This route mixes highway mileage with some local-road sections near the start or finish. There are only a few real navigation decisions along the way. The trickiest moment comes around 2.2 miles in near Carthage Point Road.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 3h 43m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 2.2 miles (Carthage Point Road): Highway fork - watch signs carefully; at 49.7 miles (LA 128 / Lee Street): Navigation decision point; at 54.7 miles (LA 4; LA 128 / Highway 4): Navigation decision point.
Greenville is a city in Washington County, Mississippi, United States. The population was 30,000 in 2020, making it the ninth largest city in the state. It is the county seat of Washington County.
Mixed highway & surface route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 42.1 miles on State Route 17. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 2.2 miles (Carthage Point Road): Highway fork - watch signs carefully; at 49.7 miles (LA 128 / Lee Street): Navigation decision point; at 54.7 miles (LA 4; LA 128 / Highway 4): Navigation decision point.
Yes — Natchez National Historical Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.7 hours each way, an in-and-out day trip would put you behind the wheel for 7.5 hours — manageable with a long break at Greenville, MS, but most travelers stay overnight.
