This 95.5-mile drive from Chesterfield, MO to Hannibal, MO takes about 1 hour and 57 minutes. With a fuel cost estimated at $15, it's an economical choice for a day trip, as it's designed for a single day of travel. You'll primarily navigate local roads, so expect a more engaging, turn-heavy experience rather than a high-speed highway cruise. This route stays within the Midwest region, offering a consistent feel throughout your journey. It's a straightforward trip perfect for a quick getaway.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
47.7 miles from Chesterfield, MO
A natural place for your longest stop of the day
, about 58m into the drive
.
Main Roads
Road
Distance
Duration
Avenue of the Saints
89.6 mi
1h 46m
Warren Barett Drive
3 mi
5m
Chesterfield Airport Road
1.2 mi
2m
Broadway
0.6 mi
1m
Baxter Road
0.3 mi
<1m
Grand Avenue
0.2 mi
<1m
Boone's Crossing
0.2 mi
<1m
Old Chesterfield Road
0.1 mi
<1m
Longest stretch:
Avenue of the Saints
— 89.6 mi, about 1h 46m
Turn-by-Turn Driving Directions
Step-by-step road directions between Chesterfield, MO and Hannibal, MO.
1
Start on Santa Maria Drive
107 ft·8 sec·Santa Maria Drive
2
Turn left onto Old Chesterfield Road
0.1 mi·32 sec·Old Chesterfield Road
3
Turn right onto Baxter Road
0.3 mi·45 sec·Baxter Road
4
At end of road, turn left onto Chesterfield Airport Road
1.1 mi·1 min·Chesterfield Airport Road
5
Continue on Chesterfield Airport Road
438 ft·8 sec·Chesterfield Airport Road
6
Turn right onto Boone's Crossing
0.2 mi·26 sec·Boone's Crossing
Use the right lane.
7
Take the ramp
167 ft·7 sec
Toward I 64 West, US 40 West, US 61 NorthUse the left lane.
8
Turn left
0.2 mi·17 sec
Toward I 64 West, US 40 West, US 61 North
9
Merge onto I 64; US 40; US 61
90 mi·1 hr 46 min·Avenue of the Saints
Use the straight lane.
10
Turn right onto Warren Barett Drive
3.0 mi·5 min·Warren Barett Drive
11
Turn left onto Grand Avenue
0.2 mi·23 sec·Grand Avenue
12
Turn right onto Broadway
0.6 mi·1 min·Broadway
13
Turn right
54 ft·3 sec
14
Arrive at destination
Trip Plan
Given its short duration of under two hours, this route offers great flexibility for departure times. You can easily make this a morning excursion or an afternoon adventure. Since there are no designated stops in the data, plan to fuel up before you leave Chesterfield, MO, as the $15 fuel cost suggests a straightforward journey. The local road nature means you'll be more connected to the communities you pass through, so keep an eye out for local signage and be mindful of varying speed limits. This drive is best enjoyed at a relaxed pace, allowing you to appreciate the local surroundings without feeling rushed.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 47.7 miles from Chesterfield, MO, or about 58m into the drive.
The longest continuous stretch on this route runs about 89.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 21 miles or 26m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 47.7 miles or 58m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 34m
Traffic, exits, and arrival timing usually matter more near Hannibal, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Chesterfield, MO so your first major turns are already loaded.
Day 1
Settle into the route from Chesterfield, MO
This is one driving day of about 95.5 miles and 1h 57m.
Your first comfortable stop window is around 21 miles from Chesterfield, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Avenue of the Saints for about 89.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 11
5 decision points cluster between mile 0 and 2.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0 mi into trip|~0m in|Old Chesterfield Road
Turn left onto Old Chesterfield Road
Navigation decision point
5
1.7 mi into trip|~3m in|Boone's Crossing
Turn right onto Boone's Crossing
Lane positioning matters here
Use the right lane.
7
1.9 mi into trip|~4m in
Take the ramp toward I 64 West, US 40 West, US 61 North
Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Toward I 64 West, US 40 West, US 61 North
6
1.9 mi into trip|~4m in
Turn left toward I 64 West, US 40 West, US 61 North
Multiple destination signs - pick the right one
Toward I 64 West, US 40 West, US 61 North
5
2.1 mi into trip|~4m in|I 64; US 40; US 61 / Avenue of the Saints
Merge onto I 64; US 40; US 61 / Avenue of the Saints
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
Fuel & Cost
Regular Gas
$14.93 one way
$29.86 round trip
$3.97/gal25.4 MPG avg33 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$16.39
$32.79
premium
$4.89
$18.38
$36.76
diesel
$5.61
$21.09
$42.17
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$15
Meals
$25–$50
Total
$40–$65
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 33.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $10 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
28.7
0
$10.03
$4.58
Efficient EV
23.9
0
$8.36
$3.82
EV Truck/SUV
38.2
0
$13.37
$6.11
Gas CO2
33 kg
EV CO2
11 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Chesterfield, MO
Late night
in Chesterfield on Sunday
Local time
2:42 AM
CDT
Current temp
57°F
Unavailable
Live forecast
Destination
Hannibal, MO
Late night
in Hannibal on Sunday
Local time
2:42 AM
CDT
Current temp
74°F
Unavailable
Live forecast
76°F
Troy, MO
48 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
17 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 57m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
The character of this drive is defined by its 'turn-heavy local drive' profile, with a 0% highway share. You won't encounter long stretches of uninterrupted driving; instead, anticipate navigating through a series of local roads, including Old Chesterfield Road, Baxter Road, and Chesterfield Airport Road. The absence of a longest uninterrupted stretch signifies a continuous engagement with the road network. This route is about experiencing the local landscape and road system directly, making for a more involved driving experience.
Only 0% highway — the rest is turn-by-turn surface driving.
14 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 89.6 mi on Avenue of the Saints.
How Hard Is This Drive?
4/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near Old Chesterfield Road.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 57m drive. You will face about 11 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (Old Chesterfield Road): Navigation decision point; at 1.7 miles (Boone's Crossing): Lane positioning matters here; at 1.9 miles: Lane positioning matters here. Multiple destination signs - pick the right one.
Hannibal is a city in Missouri. It is located approximately 100 miles northwest of St. Louis and is located on the west bank of the Mississippi River.
Hannibal is best known as the boyhood home of author Samuel Longhorn Clemens, more commonly known as Mark Twain. Twain's The Adventures of Tom Sawyer and Adventures of Huckleberry Finn are set in Hannibal. Many historical sites in the city revolve around Twain and his writings, which occupy a prominent place in the history of the Underground Railroad era.
The longest stretch is about 89.6 miles on Avenue of the Saints. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: near the start (Old Chesterfield Road): Navigation decision point; at 1.7 miles (Boone's Crossing): Lane positioning matters here; at 1.9 miles: Lane positioning matters here. Multiple destination signs - pick the right one.
Yes. A round trip is manageable in a single day if you plan a break at Hannibal, MO before heading back.
