Hannibal, MO Road Trips
Sitting in the Midwest, Hannibal, MO is a local road trip base with 5 trip routes mapped and ready to explore. Most drives stay under 101 miles, making this area well-suited for day trips and weekend getaways. Routes from Hannibal, MO spread mainly south and east, covering a wide geographic range.
Photo: Wikimedia Commons
Trip Routes
5
Longest Drive
145.9 mi
New York, MO
Quickest Drive
1h 44m
O'Fallon, MO
Plan Around Hannibal, MO
Popular Incoming Routes
Useful if Hannibal, MO is the arrival point and you want the strongest routes into the city first.
Continue From Hannibal, MO
Good next legs if this city is only one stop in a longer road trip.
Trips from Hannibal, MO
Driving from Hannibal, MO
The typical drive from Hannibal, MO covers about 101 miles and takes around 2h 4m. The majority of routes are short drives — quick enough to finish before lunch and be back for dinner. The longest mapped route runs 117 miles (2h 23m), while the shortest is just 85 miles.
Popular Destinations
The most popular drives from Hannibal, MO include St. Louis, MO (116.7 mi, 2h 23m) and O'Fallon, MO (84.9 mi, 1h 44m). Most destinations stay within the same state, perfect for exploring the local region thoroughly.
Planning & Costs
Regular gas in MO currently averages around $3.77 per gallon. For the typical 101-mile trip from Hannibal, MO, budget about $15 in fuel one way, assuming 25 MPG. Longer hauls and premium fuel will cost proportionally more.
With an average drive under three hours, you have plenty of flexibility — leave whenever it suits you. The majority of destinations are to the south. Morning starts help you avoid the midday heat on longer drives.
Frequently Asked Questions
There are 2 mapped routes leaving Hannibal, MO and 3 routes heading into Hannibal, MO, covering 5 total connections. Distances range from 85 to 117 miles.
The longest mapped route from Hannibal, MO covers 117 miles and takes approximately 2h 23m. Shorter options start at just 85 miles.
The average route from Hannibal, MO runs about 101 miles with a drive time of roughly 2h 4m. This includes both short day trips and longer multi-day drives.
At current gas prices (about $3.77/gallon for regular), the average 101-mile trip from Hannibal, MO costs roughly $15 in fuel one way, based on 25 MPG. Your actual cost depends on your vehicle's efficiency.
The most popular road trip destinations from Hannibal, MO include St. Louis, MO and O'Fallon, MO. Each route page has detailed drive times, fuel estimates, stop suggestions, and turn-by-turn directions.
Hannibal, MO by the Numbers
Recent demographic snapshot from the US Census Bureau's American Community Survey.
Population
16,825
Median Income
$54,071
Median Home Value
$126,300
Median Age
38.3
Source: US Census Bureau ACS 5-year (public domain). See our methodology for details.
Traveler Guide to Hannibal, MO
Hannibal is a city in Missouri. It is located approximately 100 miles northwest of St. Louis and is located on the west bank of the Mississippi River. Hannibal is best known as the boyhood home of author Samuel Longhorn Clemens, more commonly known as Mark Twain. Twain's The Adventures of Tom Sawyer and Adventures of Huckleberry Finn are set in Hannibal. Many historical sites in the city revolve around Twain and his writings, which occupy a prominent place in the history of the Underground Railroad era.
1 Hannibal Conventions & Visitor's Bureau, 505 N 3rd St, ☏ +1 573 221-2477. Missouri Division of Tourism, ☏ +1 573 751-4133, toll-free: +1-800-519-2100, [email protected].
1 Mark Twain Boyhood Home & Museum, 120 N Main St, ☏ +1 573 221-9010. Molly Brown Birthplace & Museum, 400 N Main St, ☏ +1 573-221-2477. $5. 2 Rockcliffe Mansion, 1000 Bird, ☏ +1 573 221-4140.
1 Mark Twain Cave Complex, 300 Cave Hollow Rd, ☏ +1 573 221-1656. 2 National Tom Sawyer Days. (updated Oct 2020) 3 Clemens Field. Baseball stadium. (updated Oct 2020) 4 Riverview Park. Contains a statue of Mark Twain. (updated Oct 2020)
Mark Twain Dinette, 3rd St & Hill St, ☏ +1 573 221-5300. The Becky Thatcher Restaurant, 213 N. 3rd Street, ☏ +1 573 221-8100.
Garth Woodside Mansion (Hannibal Bed And Breakfast), 11069 New London Road, toll-free: +1-888-427-8409. A bed and breakfast and restaurant in a beautiful mansion where Mark Twain himself stayed. Holiday Inn Express & Suites, 120 Shinn Ln, ☏ +1-573-248-3000. Check-in: 3PM, check-out: noon. Indoor pool, WiFi, and breakfast included. (updated Apr 2021)
From the south: U.S. Route 69 or U.S. Route 71. From the west: U.S. route 36 From the east: Interstate 72 From the north: U.S. Routes 61/24 Burlington Trailways operates daily buses in each direction between St. Louis and places in Iowa, stopping in Hannibal. American Airlines partner Cape Air operate flights from St. Louis to nearby (28 miles away) Quincy, Illinois.
Travel tips adapted from Hannibal on Wikivoyage, licensed CC BY-SA 4.0. Content summarized; visit the source for the full article. See our methodology for how we use it.
Trips to Hannibal, MO
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