Cafe Poland by Iwona
Near the start, right off the route
Columbia, Missouri
Hours: 5–8 pm
+17024270048
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
2h 2m
Distance
97.5 mi
157 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$15
one way
EV Charging
Good
8 stations
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Hannibal, MO
Wikimedia Commons
This 97.5-mile drive from Columbia, MO, to Hannibal, MO, is a straightforward trip, taking approximately 2 hours and 2 minutes to complete. With a modest fuel cost estimated at $15, it's an accessible journey within the Midwest region. The route predominantly utilizes highways, making it a convenient option for a single-day excursion rather than requiring an overnight stop. You'll experience a mixed driving profile, so it's a good choice if you're looking for a relatively short drive with some variation. This trip is well-suited for a day trip, allowing you to maximize your time at your destination.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
48.8 miles from Columbia, MO
A natural place for your longest stop of the day , about 1h 1m into the drive .
| Road | Distance | Duration |
|---|---|---|
| MO 19 | 27.1 mi | 30m |
| US 54 | 26.3 mi | 31m |
| Dwight D. Eisenhower Highway | 18.6 mi | 23m |
| East Liberty Street | 10.3 mi | 13m |
| Avenue of the Saints | 7.2 mi | 8m |
| Warren Barett Drive | 3 mi | 5m |
| Sheriff Roger I. Wilson Memorial Highway | 1.9 mi | 2m |
| North Providence Road | 1.2 mi | 2m |
Step-by-step road directions between Columbia, MO and Hannibal, MO.
Start on MO 163
Take the ramp
Merge onto I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Take the exit
Turn left onto US 54
At end of road, turn right onto US 54
Enter roundabout onto US 54; MO 19
Continue on US 54; MO 19
Enter roundabout onto MO 19
Continue on MO 19
Take the exit
Merge onto US 61
Turn right onto Warren Barett Drive
Turn left onto Grand Avenue
Turn right onto Broadway
Turn right
Arrive at destination
Given the 2-hour duration and 97.5-mile length, this trip is ideal for a day trip, offering flexibility in your departure time. There are no specific designated stops mentioned, so you can plan your breaks as needed. The estimated fuel cost is around $15, so factor that into your budget. Keep an eye on your fuel levels, especially during the longest stretch of 27.1 miles on MO 19, where services might be less frequent. A practical tip is to consider leaving in the mid-morning to avoid potential rush hour traffic in Columbia and arrive in Hannibal with ample daylight.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 21 miles or 27m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 48.8 miles or 1h 1m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 38m
Traffic, exits, and arrival timing usually matter more near Hannibal, MO than in the middle of the route.
Open the route before leaving Columbia, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Columbia, MO
This is one driving day of about 97.5 miles and 2h 2m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
49 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 21 miles helps settle the day before fatigue starts building.
The midpoint is around 48.8 miles from Columbia, MO, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Columbia, Missouri
Near the start, right off the route
Hours: 5–8 pm
+17024270048
Cafe Berlin
Columbia, Missouri
Cajun Crab House Seafood Restaurant
Columbia, Missouri
Near the start, right off the route
Columbia, Missouri
Hours: 5–8 pm
+17024270048
Visit websiteNear the start, right off the route
Columbia, Missouri
Hours: 8 am–2 pm
+15734410400
Visit websiteNear the start, short detour
Columbia, Missouri
Hours: 3–8 pm
+15732346277
Visit websiteNear the start, short detour
Columbia, Missouri
Hours: Open 24 hours
+18777983752
Visit websiteEarly in the drive, short detour
Kingdom City, Missouri
+15733106020
Visit websiteNear the end, short detour
Hannibal, Missouri
Hours: Open 24 hours
+18777983752
Visit websiteEarly in the drive, short detour
Kingdom City, Missouri
Hours: Open 24 hours
+18887584389
Visit websiteNear the start, short detour
Columbia, Missouri
Hours: Open 24 hours
+18889982546
Visit websiteNear the start, short detour
Columbia, Missouri
Hours: Open 24 hours
+18337484267
Visit websiteNear the start, short detour
Columbia, Missouri
Hours: Open 24 hours
+18887584389
Visit websiteNear the start, short detour
Columbia, Missouri
Hours: Open 24 hours
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 1.2 and 86.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the ramp toward I 70 East, US 40 East: Saint Louis
Multiple destination signs - pick the right one
Take the exit toward US 54: Auxvasse, Mexico, Fulton
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
At end of road, turn right onto US 54 / East Liberty Street
Navigation decision point
Enter roundabout onto US 54; MO 19
Roundabout - know your exit number before entering
Take the exit
Exit ramp - move to the correct lane early
Regular Gas
$15.24 one way
$30.49 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $16.74 | $33.47 |
| premium | $4.89 | $18.76 | $37.53 |
| diesel | $5.61 | $21.53 | $43.05 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$15
Meals
$25–$50
Total
$40–$65
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 34.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $10 in charging · 0 stops · 68% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 29.3 | 0 | $10.24 | $4.68 |
| Efficient EV | 24.4 | 0 | $8.53 | $3.90 |
| EV Truck/SUV | 39 | 0 | $13.65 | $6.24 |
Gas CO2
34 kg
EV CO2
11 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Columbia on Sunday
Local time
2:44 AM
CDT
Current temp
74°F
Unavailable
Destination
Late night in Hannibal on Sunday
Local time
2:44 AM
CDT
Current temp
74°F
Unavailable
73°F
Vandalia, MO
49 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
Both ends of the route are sitting at about the same temperature right now.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
The character of this drive is a blend, with 55% of the journey on highways. You'll encounter stretches on MO 19, US 54, and the Dwight D. Eisenhower Highway. The longest uninterrupted segment you'll navigate is 27.1 miles along MO 19, offering a consistent stretch of road. This mixed profile means you'll experience both faster highway driving and potentially more local road sections, providing a dynamic feel behind the wheel. The road offers a varied experience without being overly demanding.
This route mixes highway mileage with some local-road sections near the start or finish. There are only a few real navigation decisions along the way. The trickiest moment comes around 1.2 miles in.
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 2h 2m drive. You will face about 12 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 1.2 miles: Multiple destination signs - pick the right one; at 22.4 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 40.7 miles (US 54 / East Liberty Street): Navigation decision point.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Columbia, MO and Hannibal, MO, road signs point toward Mexico and Fulton.
Mexico
Fulton
Columbia is a bustling college town in Missouri, halfway between St. Louis and Kansas City. It is home of the University of Missouri (also known as 'Mizzou') as well as two other post-secondary institutions Stephens College and Columbia College.
Hannibal is a city in Missouri. It is located approximately 100 miles northwest of St. Louis and is located on the west bank of the Mississippi River. Hannibal is best known as the boyhood home of author Samuel Longhorn Clemens, more commonly known as Mark Twain. Twain's The Adventures of Tom Sawyer and Adventures of Huckleberry Finn are set in Hannibal. Many historical sites in the city revolve around Twain and his writings, which occupy a prominent place in the history of the Underground Railroad era.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 2h 2m. Total distance: 97.5 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 2m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (55%). Straightforward navigation.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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