McComb, MS to City of Greenville, MS is 196 miles and takes about 3h 54m via I 55 and US 49W, with a fuel budget near $27 and enough daylight to finish in a day. This trip primarily keeps you within Mississippi, moving from the Southeast region to another part of the Southeast. Expect a drive that's largely highway-focused, making it a straightforward journey if you're looking for efficiency. With a recommended one-day duration, you can comfortably complete this route without needing an overnight stay, focusing on reaching your destination smoothly.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
98 miles from McComb, MS
A natural place for your longest stop of the day
, about 1h 51m into the drive
.
Main Roads
Road
Distance
Duration
I 55
72.9 mi
1h 18m
US 49W
46.7 mi
56m
Medgar Evers Boulevard
39.5 mi
48m
US 82
15.8 mi
19m
MS 182
8.3 mi
12m
US 49
5.5 mi
6m
I 20
2.4 mi
2m
Martin Luther King Junior Boulevard
1 mi
1m
Longest stretch:
I 55
— 72.9 mi, about 1h 18m
Turn-by-Turn Driving Directions
Step-by-step road directions between McComb, MS and City of Greenville, MS.
1
Start on Main Street
327 ft·19 sec·Main Street
2
Turn left onto North Front Street
478 ft·28 sec·North Front Street
3
Turn left onto State Street
473 ft·13 sec·State Street
4
Turn right onto US 51
0.4 mi·40 sec·North Broadway Street
5
Turn left onto US 51
0.3 mi·31 sec·West Georgia Avenue
6
Continue on US 51
0.4 mi·35 sec·Jackson Avenue
7
Continue on US 51
0.3 mi·29 sec·Mississippi Street
8
Continue on US 51
0.4 mi·36 sec·Northwest Street
9
Turn left onto MS 570
0.5 mi·1 min·Smithdale Road
10
Take the ramp
0.2 mi·22 sec
11
Merge onto I 55; US 98
73 mi·1 hr 17 min·I 55; US 98
12
Keep slight right at fork onto I 55
0.2 mi·13 sec·I 55
13
Take the exit
0.2 mi·22 sec
Exit 92CToward I 20 West, US 49 North: Vicksburg, Yazoo City
14
Keep slight left at fork
0.2 mi·29 sec
Toward I 20 West, US 49 North: Vicksburg, Yazoo City
15
Merge onto I 20; US 49
2.4 mi·2 min·I 20; US 49
16
Take the exit onto US 49
5.2 mi·6 min·US 49
Toward I 220 North, I 49 North: North Jackson, Yazoo City
17
Take the exit onto US 49
0.3 mi·33 sec·US 49
Toward US 49 North: Yazoo City
18
Merge onto US 49
39 mi·48 min·Medgar Evers Boulevard
19
Take the exit onto US 49W
47 mi·56 min·US 49W
Toward US 49W North, MS 3 South: Indianola, Vicksburg
20
Turn left onto US 82
2.4 mi·3 min·US 82
21
Keep slight left at fork onto US 82
0.4 mi·29 sec·US 82
22
Keep slight left at fork onto US 82
13 mi·15 min·US 82
23
Turn right onto MS 182
8.3 mi·12 min·MS 182
24
Turn left onto MS 1
1.0 mi·1 min·Martin Luther King Junior Boulevard
25
Turn right onto East Reed Road
0.7 mi·1 min·East Reed Road
26
Turn left onto Sandy Avenue
46 ft·2 sec·Sandy Avenue
27
Arrive at destination
Sandy Avenue
Trip Plan
Given the 3h 54m estimated drive time and 196-mile distance, this trip is easily achievable in a single day. Aim to depart in the morning to maximize daylight and allow for an unhurried pace. With only one suggested stop, you have considerable flexibility; consider a mid-drive break around the halfway point or closer to the transition from I 55 to US 49W. Keep an eye on your fuel level, especially before the longest stretch on I 55, as services can be more spread out on interstate segments.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 98 miles from McComb, MS, or about 1h 51m into the drive.
The longest continuous stretch on this route runs about 72.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 43 miles or 48m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 98 miles or 1h 51m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 8m
Traffic, exits, and arrival timing usually matter more near City of Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving McComb, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from McComb, MS
This is one driving day of about 196 miles and 3h 54m.
Your first comfortable stop window is around 43 miles from McComb, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 55 for about 72.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 19
5 decision points cluster between mile 0.1 and 78.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.1 mi into trip|~0m in|North Front Street
Turn left onto North Front Street
Navigation decision point
5
0.2 mi into trip|~0m in|State Street
Turn left onto State Street
Navigation decision point
7
75.7 mi into trip|~1h 23m in
Take the exit toward I 20 West, US 49 North: Vicksburg, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 92C
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
7
75.8 mi into trip|~1h 23m in
Keep slight left at fork toward I 20 West, US 49 North: Vicksburg, Yazoo City
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
5
78.5 mi into trip|~1h 27m in|US 49
Take the exit onto US 49 toward I 220 North, I 49 North: North Jackson, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward I 220 North, I 49 North: North Jackson,...
Fuel & Cost
Regular Gas
$29.60 one way
$59.20 round trip
$3.84/gal25.4 MPG avg69 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$32.49
$64.99
premium
$4.56
$35.18
$70.36
diesel
$5.61
$43.27
$86.55
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 68.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $21 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
58.8
0
$20.58
$9.41
Efficient EV
49
0
$17.15
$7.84
EV Truck/SUV
78.4
0
$27.44
$12.54
Gas CO2
69 kg
EV CO2
23 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
McComb, MS
Morning
in McComb on Sunday
Local time
8:27 AM
CDT
Current temp
80°F
Unavailable
Live forecast
Destination
City of Greenville, MS
Morning
in City of Greenville on Sunday
Local time
8:27 AM
CDT
Current temp
80°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
Very similar conditions
Both ends of the route are sitting at about the same temperature right now.
Road read
3h 54m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This is a highway-focused drive, with 77% of the route utilizing major roadways. You'll spend a significant portion of your time on I 55, including a stretch of 72.9 miles without needing to exit. As you transition to US 49W, the driving experience may shift slightly, but the overall character remains geared towards covering distance efficiently. The road generally progresses by moving you north through Mississippi on well-maintained highways.
77% highway — fuel and pacing are the main things to plan.
27 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 72.9 mi on I 55.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on I 55 and US 49W. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near North Front Street.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 19 significant decision points across 196 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (North Front Street): Navigation decision point; at 0.2 miles (State Street): Navigation decision point; at 75.7 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between McComb, MS and City of Greenville, MS, road signs point toward Yazoo City and Vicksburg.
Yazoo City
75.7 mi in|~1h 23m
Vicksburg
123.4 mi in|~2h 22m|via US 49W
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 54m. Total distance: 196 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 54m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (77%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 72.9 miles on I 55. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at City of Greenville, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.1 miles (North Front Street): Navigation decision point; at 0.2 miles (State Street): Navigation decision point; at 75.7 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Yes — Medgar and Myrlie Evers Home National Monument. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.9 hours each way, an in-and-out day trip would put you behind the wheel for 7.8 hours — manageable with a long break at City of Greenville, MS, but most travelers stay overnight.
