Traveling from Crystal Springs to Greenville takes you across 143 miles of Mississippi landscape in approximately 2 hours and 56 minutes. This route is best suited as a single-day excursion, as the manageable travel time allows for a straightforward trip without the need for an overnight stay. You will primarily navigate via I-55, Medgar Evers Boulevard, and US 49W, spending about 70% of your time on highways. Budgeting around $22 for fuel should cover your transit costs comfortably. Whether you are heading north for business or a change of scenery, this highway-focused drive offers a clear, predictable path through the Southeast.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
71.5 miles from Crystal Springs, MS
A natural place for your longest stop of the day
, about 1h 26m into the drive
.
Main Roads
Road
Distance
Duration
US 49W
46.7 mi
56m
Medgar Evers Boulevard
39.5 mi
48m
I 55
19.9 mi
21m
US 82
15.8 mi
19m
MS 182
8.3 mi
12m
US 49
5.5 mi
6m
I 20
2.4 mi
2m
US 51
1.9 mi
2m
Longest stretch:
US 49W
— 46.7 mi, about 56m
Turn-by-Turn Driving Directions
Step-by-step road directions between Crystal Springs, MS and City of Greenville, MS.
1
Start on East Georgetown Street
0.5 mi·59 sec·East Georgetown Street
2
Turn right onto US 51
1.5 mi·2 min·US 51
3
Turn left onto US 51; MS 27
0.3 mi·35 sec·US 51; MS 27
4
Take the ramp
0.3 mi·43 sec
Toward I 55 North, US 51 North
5
Merge onto I 55; US 51
20 mi·21 min·I 55; US 51
6
Keep slight right at fork onto I 55
0.2 mi·13 sec·I 55
7
Take the exit
0.2 mi·22 sec
Exit 92CToward I 20 West, US 49 North: Vicksburg, Yazoo City
8
Keep slight left at fork
0.2 mi·29 sec
Toward I 20 West, US 49 North: Vicksburg, Yazoo City
9
Merge onto I 20; US 49
2.4 mi·2 min·I 20; US 49
10
Take the exit onto US 49
5.2 mi·6 min·US 49
Toward I 220 North, I 49 North: North Jackson, Yazoo City
11
Take the exit onto US 49
0.3 mi·33 sec·US 49
Toward US 49 North: Yazoo City
12
Merge onto US 49
39 mi·48 min·Medgar Evers Boulevard
13
Take the exit onto US 49W
47 mi·56 min·US 49W
Toward US 49W North, MS 3 South: Indianola, Vicksburg
14
Turn left onto US 82
2.4 mi·3 min·US 82
15
Keep slight left at fork onto US 82
0.4 mi·29 sec·US 82
16
Keep slight left at fork onto US 82
13 mi·15 min·US 82
17
Turn right onto MS 182
8.3 mi·12 min·MS 182
18
Turn left onto MS 1
1.0 mi·1 min·Martin Luther King Junior Boulevard
19
Turn right onto East Reed Road
0.7 mi·1 min·East Reed Road
20
Turn left onto Sandy Avenue
46 ft·2 sec·Sandy Avenue
21
Arrive at destination
Sandy Avenue
Trip Plan
Planning your departure is simple given the sub-three-hour duration, but aiming for mid-morning helps you avoid potential congestion on the highway sections. Since the route includes one recommended stop, use that time to stretch your legs during the longest 46.7-mile stretch on US 49W to keep your energy up. Keep an eye on your fuel gauge before leaving Crystal Springs, as the $22 estimated cost is based on standard highway consumption. Because this is a relatively short trip, you have the flexibility to adjust your schedule to suit your personal pace. Always check local traffic conditions on I-55 before you head out to ensure your travel time remains close to the 2-hour and 56-minute estimate.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 71.5 miles from Crystal Springs, MS, or about 1h 26m into the drive.
The longest continuous stretch on this route runs about 46.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 31 miles or 36m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 71.5 miles or 1h 26m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 22m
Traffic, exits, and arrival timing usually matter more near City of Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Crystal Springs, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Crystal Springs, MS
This is one driving day of about 143 miles and 2h 56m.
Your first comfortable stop window is around 31 miles from Crystal Springs, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 49W for about 46.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 2.4 and 70.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
2.4 mi into trip|~3m in
Take the ramp toward I 55 North, US 51 North
Multiple destination signs - pick the right one
Toward I 55 North, US 51 North
7
22.6 mi into trip|~25m in
Take the exit toward I 20 West, US 49 North: Vicksburg, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 92C
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
7
22.8 mi into trip|~26m in
Keep slight left at fork toward I 20 West, US 49 North: Vicksburg, Yazoo City
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 20 West, US 49 North: Vicksburg, Yazoo...
5
25.4 mi into trip|~29m in|US 49
Take the exit onto US 49 toward I 220 North, I 49 North: North Jackson, Yazoo City
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward I 220 North, I 49 North: North Jackson,...
5
70.4 mi into trip|~1h 24m in|US 49W
Take the exit onto US 49W toward US 49W North, MS 3 South: Indianola, Vicksburg
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 49W North, MS 3 South: Indianola, Vic...
Fuel & Cost
Regular Gas
$21.60 one way
$43.19 round trip
$3.84/gal25.4 MPG avg50 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$23.71
$47.42
premium
$4.56
$25.67
$51.33
diesel
$5.61
$31.57
$63.15
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$22
Meals
$25–$50
Total
$47–$72
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 50 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $15 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
42.9
0
$15.01
$6.86
Efficient EV
35.8
0
$12.51
$5.72
EV Truck/SUV
57.2
0
$20.02
$9.15
Gas CO2
50 kg
EV CO2
17 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 14, 2026
Origin
Crystal Springs, MS
Night
in Crystal Springs on Saturday
Local time
10:14 PM
CDT
Current temp
78°F
Unavailable
Live forecast
Destination
City of Greenville, MS
Night
in City of Greenville on Saturday
Local time
10:14 PM
CDT
Current temp
86°F
Sunny
SSW 10 mph1% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 56m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
Expect a drive that transitions from interstate travel to regional highway cruising. Roughly 70% of the journey is highway-based, providing a consistent pace for the majority of your 143-mile trip. You will encounter your longest uninterrupted stretch on US 49W, which spans 46.7 miles of the total distance. The personality of the road shifts as you move between the segments of I-55 and the regional corridors, requiring you to stay alert during the transition points. It is a functional, highway-heavy route that prioritizes efficiency over technical, winding backroads.
70% highway — fuel and pacing are the main things to plan.
21 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 46.7 mi on US 49W.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on US 49W and Medgar Evers Boulevard. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 2.4 miles in.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 143 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 2.4 miles: Multiple destination signs - pick the right one; at 22.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 22.8 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
463 ft108 ft
Total Climb
174 ft
Total Descent
511 ft
Highest Point
463 ft
Elevation Range
356 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Crystal Springs, MS and City of Greenville, MS, road signs point toward Yazoo City and Vicksburg.
Yazoo City
22.6 mi in|~25m
Vicksburg
70.4 mi in|~1h 24m|via US 49W
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 56m. Total distance: 143 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
2h 56m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (70%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 46.7 miles on US 49W. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at City of Greenville, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 2.4 miles: Multiple destination signs - pick the right one; at 22.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 22.8 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Yes. A round trip is manageable in a single day if you plan a break at City of Greenville, MS before heading back.
