If you are planning to travel from Clinton to Greenville, expect a straightforward 113.9-mile journey across Mississippi. This trip typically takes about 2 hours and 5 minutes to complete, making it a perfect candidate for a single-day excursion. You won't need an overnight stay, as the distance is easily manageable in one go. Budgeting roughly $17 for fuel should cover your needs for this trek through the Southeast. Whether you are heading out for business or a quick visit, this drive offers a simple, direct connection between the two cities.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
56.8 miles from Clinton, MS
A natural place for your longest stop of the day
, about 1h 14m into the drive
.
Main Roads
Road
Distance
Duration
US 49W
46.7 mi
56m
US 49
34.1 mi
41m
US 82
15.8 mi
19m
MS 182
9.2 mi
13m
Pinehaven Road
5.4 mi
9m
South Main Street
0.9 mi
2m
Clinton Parkway
0.8 mi
1m
Dunton Road
0.3 mi
1m
Longest stretch:
US 49W
— 46.7 mi, about 56m
Turn-by-Turn Driving Directions
Step-by-step road directions between Clinton, MS and Greenville, MS.
1
Start on Dunton Road
0.3 mi·1 min·Dunton Road
2
Continue on East Leake Street
0.2 mi·44 sec·East Leake Street
3
Turn left onto East Street
0.1 mi·30 sec·East Street
4
Turn left onto East Main Street
366 ft·16 sec·East Main Street
5
Turn left onto Clinton Parkway
0.8 mi·1 min·Clinton Parkway
6
Continue on Pinehaven Road
5.4 mi·9 min·Pinehaven Road
7
At end of road, turn left onto US 49
34 mi·41 min·US 49
8
Take the exit onto US 49W
47 mi·56 min·US 49W
Toward US 49W North, MS 3 South: Indianola, Vicksburg
9
Turn left onto US 82
2.4 mi·3 min·US 82
10
Keep slight left at fork onto US 82
0.4 mi·29 sec·US 82
11
Keep slight left at fork onto US 82
13 mi·15 min·US 82
12
Turn right onto MS 182
9.2 mi·13 min·MS 182
13
Turn right onto South Main Street
0.9 mi·2 min·South Main Street
14
Turn right onto MS 814
10 ft·0 sec·South Broadway Street
15
Arrive at destination
MS 814
Trip Plan
Since this is a relatively short trip, you have plenty of flexibility regarding your departure time. You can easily complete the entire 2-hour and 5-minute drive without needing to plan for significant rest stops, though it is always wise to keep an eye on your fuel gauge before heading out. Given the turn-heavy nature of the route, double-check your GPS settings before leaving Clinton to ensure you stay on the correct path through the local streets. If you prefer to avoid heavy traffic, try to schedule your departure during off-peak hours to keep your transit time efficient. Taking the time to map out your specific turns on East Leake, East, and East Main Streets will help you navigate the route with confidence.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 56.8 miles from Clinton, MS, or about 1h 14m into the drive.
The longest continuous stretch on this route runs about 46.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 25 miles or 35m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 56.8 miles or 1h 14m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 59m
Traffic, exits, and arrival timing usually matter more near Greenville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Clinton, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Clinton, MS
This is one driving day of about 113.6 miles and 2h 27m.
Your first comfortable stop window is around 25 miles from Clinton, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 49W for about 46.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Home stretch
2.6 mi from route
~7 min detour
$20 to $30
Leland, Mississippi
Hours: 4:30–8:30 pm
+16626864401
Birthplace Of Kermit The Frog Museum
4.5
★ ★ ★ ★ ★
Near the end, short detour
Home stretch
2.2 mi from route
~5 min detour
Leland, Mississippi
Hours: 10 am–4 pm
+16626867383
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 9
5 decision points cluster between mile 0.4 and 90.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.4 mi into trip|~1m in|East Street
Turn left onto East Street
Navigation decision point
4
0.5 mi into trip|~2m in|East Main Street
Turn left onto East Main Street
Navigation decision point
5
40.9 mi into trip|~55m in|US 49W
Take the exit onto US 49W toward US 49W North, MS 3 South: Indianola, Vicksburg
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 49W North, MS 3 South: Indianola, Vic...
4
90 mi into trip|~1h 55m in|US 82
Keep slight left at fork onto US 82
Highway fork - watch signs carefully
4
90.4 mi into trip|~1h 55m in|US 82
Keep slight left at fork onto US 82
Highway fork - watch signs carefully
Fuel & Cost
Regular Gas
$17.16 one way
$34.31 round trip
$3.84/gal25.4 MPG avg40 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$18.83
$37.67
premium
$4.56
$20.39
$40.78
diesel
$5.61
$25.08
$50.16
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$17
Meals
$25–$50
Total
$42–$67
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 39.7 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $12 in charging
· 0 stops
· 68% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
34.1
0
$11.93
$5.45
Efficient EV
28.4
0
$9.94
$4.54
EV Truck/SUV
45.4
0
$15.90
$7.27
Gas CO2
40 kg
EV CO2
13 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Clinton, MS
Late night
in Clinton on Tuesday
Local time
4:15 AM
CDT
Current temp
84°F
Unavailable
Live forecast
Destination
Greenville, MS
Late night
in Greenville on Tuesday
Local time
4:15 AM
CDT
Current temp
79°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
5 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 27m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
Expect a turn-heavy local drive rather than a monotonous interstate cruise, as this route features a 0% highway share. You will navigate primarily via East Leake Street, East Street, and East Main Street to reach your destination. Because the path relies on local roads, you should prepare for a more hands-on experience behind the wheel compared to a standard high-speed commute. The road lacks long, uninterrupted stretches, requiring your full attention as you transition through the local segments. This is a journey defined by its local character and navigation through town centers.
94% highway — fuel and pacing are the main things to plan.
15 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 46.7 mi on US 49W.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on US 49W and US 49. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.4 miles in near East Street.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 2h 27m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 0.4 miles (East Street): Navigation decision point; at 0.5 miles (East Main Street): Navigation decision point; at 40.9 miles (US 49W): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Clinton, MS to Greenville, MS, road signs begin pointing toward Vicksburg along the way.
Greenville is a city in Washington County, Mississippi, United States. The population was 30,000 in 2020, making it the ninth largest city in the state. It is the county seat of Washington County.
The longest stretch is about 46.7 miles on US 49W. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 0.4 miles (East Street): Navigation decision point; at 0.5 miles (East Main Street): Navigation decision point; at 40.9 miles (US 49W): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Yes. A round trip is manageable in a single day if you plan a break at Greenville, MS before heading back.
