Maine Road Trips
Maine has 61 mapped road trip routes covering cities across the state. Major departure hubs include Caribou, ME, Biddeford, ME and South Portland, ME. The average drive from a Maine city covers about 292 miles, with options ranging from quick day trips to multi-day cross-state adventures.
Routes
61
Avg Distance
292 mi
Longest Drive
1084 mi
Dayton, ME → Chicago, IL
Quickest Drive
4h 4m
Hodgdon, ME → Lewiston, ME
Maine Route Map
Featured Maine Trips
Hand-picked routes for the best Maine driving experiences.
Major Hubs in Maine
Browse city-level route pages with detailed trip planning for each hub.
Cross-State Routes
Longer drives heading out of Maine — fuel planning and overnight stops recommended.
All Routes from Maine
Dayton, ME → Chicago, IL
Van Buren, ME → Sanford, ME
Biddeford, ME → Frenchville, ME
York Beach, ME → Presque Isle, ME
Biddeford, ME → Caribou, ME
Sanford, ME → Easton, ME
Caribou, ME → Saco, ME
West Scarborough, ME → Limestone, ME
Caribou, ME → Gorham, ME
Madawaska, ME → Auburn, ME
Caribou, ME → Scarborough, ME
Caribou, ME → Westbrook, ME
Caribou, ME → City of Portland, ME
Portland, ME → Madawaska, ME
South Portland, ME → Caribou, ME
Presque Isle, ME → Saco, ME
South Portland, ME → Washburn, ME
Fort Fairfield, ME → West Scarborough, ME
Caribou, ME → Portland, ME
Easton, ME → Biddeford, ME
Scarborough, ME → Fort Fairfield, ME
Sanford, ME → Ashland, ME
Lewiston, ME → Van Buren, ME
Fort Fairfield, ME → South Portland Gardens, ME
Caribou, ME → Falmouth, ME
Presque Isle, ME → Scarborough, ME
West Scarborough, ME → Easton, ME
Auburn, ME → Fort Kent, ME
Scarborough, ME → Easton, ME
Brunswick, ME → Fort Kent, ME
Presque Isle, ME → South Portland, ME
South Portland, ME → Easton, ME
Falmouth, ME → Presque Isle, ME
Houlton, ME → Sanford, ME
Mars Hill, ME → Scarborough, ME
Auburn, ME → Caribou, ME
Brunswick, ME → Caribou, ME
Caribou, ME → Lewiston, ME
Washburn, ME → Auburn, ME
Biddeford, ME → Eastport, ME
Biddeford, ME → Houlton, ME
Presque Isle, ME → Brunswick, ME
Lewiston, ME → Easton, ME
Hodgdon, ME → South Portland Gardens, ME
South Portland, ME → Hodgdon, ME
South Portland Gardens, ME → Eastport, ME
Lewiston, ME → Mars Hill, ME
Biddeford, ME → Calais, ME
Woodland, ME → Biddeford, ME
West Scarborough, ME → Calais, ME
City of Portland, ME → Lubec, ME
Sanford, ME → Jonesport, ME
Lubec, ME → South Portland, ME
City of Portland, ME → Calais, ME
Caribou, ME → Waterville, ME
Hodgdon, ME → Lewiston, ME
South Portland, ME → Calais, ME
Eastport, ME → Lewiston, ME
Portland, ME → Calais, ME
Sanford, ME → Medway, ME
Routes to Maine
Cincinnati, OH → Augusta, ME
Van Buren, ME → Sanford, ME
Biddeford, ME → Frenchville, ME
York Beach, ME → Presque Isle, ME
Biddeford, ME → Caribou, ME
Sanford, ME → Easton, ME
Caribou, ME → Saco, ME
West Scarborough, ME → Limestone, ME
Caribou, ME → Gorham, ME
Madawaska, ME → Auburn, ME
Caribou, ME → Scarborough, ME
Caribou, ME → Westbrook, ME
Caribou, ME → City of Portland, ME
Portland, ME → Madawaska, ME
South Portland, ME → Caribou, ME
Presque Isle, ME → Saco, ME
South Portland, ME → Washburn, ME
Fort Fairfield, ME → West Scarborough, ME
Caribou, ME → Portland, ME
Easton, ME → Biddeford, ME
Scarborough, ME → Fort Fairfield, ME
Sanford, ME → Ashland, ME
Lewiston, ME → Van Buren, ME
Fort Fairfield, ME → South Portland Gardens, ME
Maine Road Trip Guides
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