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Trip from LaFollette, TN to Knoxville, TN

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

49m

Distance

39.4 mi

63 km

Drive Score

7/10

Good drive

Same Day?

Yes, doable

Fuel Cost

$6

one way

EV Charging

Unknown

Best Time to Leave

Save up to 12 min
4 AM
0h 46m ★
6 AM
0h 50m
8 AM
0h 58m
10 AM
0h 53m
12 PM
0h 52m
3 PM
0h 53m
5 PM
0h 58m
8 PM
0h 47m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in Campbell County, Tennessee, United States of America

LaFollette, TN

Wikimedia Commons

city and county seat of Knox County, State of Tennessee, United States

Knoxville, TN

Wikimedia Commons

Trip Overview

If you are traveling from LaFollette to Knoxville, you are looking at a straightforward 39.4-mile journey through the Southeast. Plan for approximately 49 minutes of driving time, making this an ideal day trip that requires no overnight stops. Budgeting about $6 for fuel is sufficient for this direct trek. By utilizing US 25W, West Central Avenue, and Jacksboro Pike, you will navigate efficiently between these two Tennessee locales. This is a practical, no-nonsense route that connects a smaller community to the larger city of Knoxville with minimal fuss.

Main Roads

Road Distance Duration
US 25W 26.9 mi 32m
West Central Avenue 3.8 mi 4m
Jacksboro Pike 3.3 mi 5m
I 275 2.9 mi 3m
East Central Avenue 0.8 mi 1m
Jackson Pike 0.3 mi <1m
Henley Street 0.3 mi <1m
Royal Blue Road 0.1 mi <1m
Longest stretch: US 25W — 26.9 mi, about 32m

Turn-by-Turn Driving Directions

Step-by-step road directions between LaFollette, TN and Knoxville, TN.

1

Start on SR 63

0.8 mi · 1 min · East Central Avenue
2

Continue on US 25W; SR 63

0.3 mi · 19 sec · Jackson Pike
3

Continue on US 25W; SR 63

3.3 mi · 5 min · Jacksboro Pike
4

Continue on US 25W; TN 63

3.8 mi · 4 min · West Central Avenue
5

Continue on US 25W; TN 63

0.1 mi · 8 sec · Royal Blue Road
6

Take the exit onto US 25W

27 mi · 32 min · US 25W
Toward Knoxville
7

Continue on I 275

2.9 mi · 3 min · I 275
8

Keep slight right at fork

0.3 mi · 29 sec
Toward I 40 East, US 441 South: Asheville, Henley Street
9

Keep slight right at fork

0.1 mi · 15 sec
Toward US 441 South: Henley Street
10

Keep slight left at fork

0.5 mi · 1 min
11

Continue on US 441

0.2 mi · 27 sec · Henley Street
Use the straight lane.
12

Continue on US 441

255 ft · 11 sec · Henley Street
13

Arrive at destination

US 441

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Rocky Top, TN, TN

Mid-route town

Meal stop

Rocky Top, TN

20 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Brentwood, TN

Fuel and coffee

A short stop after about 39 miles helps settle the day before fatigue starts building.

Norris, TN

Meal break

The midpoint is around 19.7 miles from LaFollette, TN, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

4 of 4

4 decision points cluster between mile 8.4 and 38.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

4
8.4 mi into trip | ~11m in | US 25W

Take the exit onto US 25W toward Knoxville

Exit ramp - move to the correct lane early

Toward Knoxville
6
38.1 mi into trip | ~47m in

Keep slight right at fork toward I 40 East, US 441 South: Asheville, Henley Street

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 40 East, US 441 South: Asheville, Henl...
6
38.4 mi into trip | ~47m in

Keep slight right at fork toward US 441 South: Henley Street

Highway fork - watch signs carefully

Toward US 441 South: Henley Street
4
38.5 mi into trip | ~47m in

Keep slight left at fork

Highway fork - watch signs carefully

Fuel & Cost

Regular Gas

$6.16 one way

$12.32 round trip

$3.97/gal 25.4 MPG avg 14 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $6.76 $13.53
premium $4.89 $7.58 $15.16
diesel $5.61 $8.70 $17.40

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$6

Estimated CO2 emission: 13.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $4 in charging · 0 stops · 64% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 11.8 0 $4.14 $1.89
Efficient EV 9.9 0 $3.45 $1.58
EV Truck/SUV 15.8 0 $5.52 $2.52

Gas CO2

14 kg

EV CO2

5 kg (64% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 18, 2026

Origin

LaFollette, TN

Late night in LaFollette on Sunday

Local time

12:26 AM

EDT

Current temp

82°F

Unavailable

Live forecast

Destination

Knoxville, TN

Late night in Knoxville on Sunday

Local time

12:26 AM

EDT

Current temp

74°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

8 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

49m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

This highway-focused drive is dominated by high-speed transit, with roughly 76% of the trip spent on main thoroughfares. You will spend the bulk of your time on US 25W, which features a significant 26.9-mile uninterrupted stretch. Expect a transition from the local character of Jacksboro Pike and West Central Avenue to the faster pace of the highway system. Behind the wheel, the experience is consistent and steady, moving you quickly through the regional landscape without the need for constant navigation changes.

76% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 26.9 mi on US 25W.

How Hard Is This Drive?

5/10

This is a straightforward highway drive that stays mostly on US 25W and West Central Avenue. You will hit about 4 points where you need to pay attention to lane position or signs. The trickiest moment comes around 8.4 miles in near US 25W.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 39.4 miles you will encounter 4 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 8.4 miles (US 25W): Exit ramp - move to the correct lane early; at 38.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 38.4 miles: Highway fork - watch signs carefully.

About the Cities

Arriving in Knoxville, TN

Full guide →

Knoxville, in Knox County, is the third-largest city in Tennessee. It is the home of the University of Tennessee's primary campus (UTK) and site of the 1982 World's Fair.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 49m. Total distance: 39.4 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

49m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (76%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 26.9 miles on US 25W. The full list of main roads is in the Roads section above.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: at 8.4 miles (US 25W): Exit ramp - move to the correct lane early; at 38.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 38.4 miles: Highway fork - watch signs carefully.

Yes. A round trip is manageable in a single day if you plan a break at Knoxville, TN before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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