Origin
Yarmouth, ME
Morning in Yarmouth on Sunday
Local time
6:00 AM
EDT
Current temp
53°F
Unavailable
Live forecast
Trip from Yarmouth, ME to Sanford, ME
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
58m
Distance
44.7 mi
72 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$7
one way
EV Charging
Unknown
Best Time to Leave
4 AM
0h 54m
★
6 AM
0h 58m
8 AM
1h 8m
10 AM
1h 2m
12 PM
1h 1m
3 PM
1h 2m
5 PM
1h 7m
8 PM
0h 55m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Yarmouth, ME
Jan van der Wolf
Sanford, ME
Wikimedia Commons
Trip Overview
Yarmouth, ME to Sanford, ME is 44.7 miles and takes about 58m via I 295 and Maine Turnpike, with a fuel budget near $7 and enough daylight to finish in a day. This trip stays within the Northeast region, specifically Maine, making it a straightforward local excursion. The route is primarily highway, offering a quick connection between these two points. Given its short distance and duration, it's ideal for a same-day trip without feeling rushed.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 295 | 15.5 mi | 20m |
| Maine Turnpike | 11.6 mi | 12m |
| Alfred Road | 8.2 mi | 9m |
| Sanford Road | 2.4 mi | 3m |
| Biddeford Road | 1.8 mi | 2m |
| Alfred Street | 1.4 mi | 1m |
| Cottage Street | 1.2 mi | 3m |
| Route 1 | 1 mi | 1m |
Longest stretch:
I 295
— 15.5 mi, about 20m
Turn-by-Turn Driving Directions
Step-by-step road directions between Yarmouth, ME and Sanford, ME.
1
Start on US 1
1.0 mi
·
1 min
·
Route 1
2
Take the ramp
0.4 mi
·
56 sec
3
Merge onto I 295
13 mi
·
16 min
·
I 295
Use the straight lane.
4
Keep slight left at fork onto I 295
2.6 mi
·
3 min
·
I 295
5
Merge onto I 95
12 mi
·
12 min
·
Maine Turnpike
6
Take the exit
0.7 mi
·
1 min
Exit 32
Toward ME 111: Biddeford
7
Turn right onto ME 111
1.4 mi
·
1 min
·
Alfred Street
8
Continue on ME 111
8.2 mi
·
9 min
·
Alfred Road
9
Continue on ME 111
1.8 mi
·
2 min
·
Biddeford Road
10
Continue on US 202; ME 4A
2.4 mi
·
3 min
·
Sanford Road
Use the left / straight / right lanes.
11
Continue on US 202; ME 4A
1.2 mi
·
3 min
·
Cottage Street
12
Turn left onto River Street
0.2 mi
·
26 sec
·
River Street
13
Continue on Washington Street
0.1 mi
·
25 sec
·
Washington Street
14
Turn left
89 ft
·
6 sec
15
Arrive at destination
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
22 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 10 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 22.3 miles from Yarmouth, ME, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 75 decision points cluster between mile 1.5 and 44.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
1.5 mi into trip
|
~2m in
|
I 295
Merge onto I 295
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
4
14.3 mi into trip
|
~19m in
|
I 295
Keep slight left at fork onto I 295
Highway fork - watch signs carefully
5
28.5 mi into trip
|
~35m in
Take the exit toward ME 111: Biddeford
Exit ramp - move to the correct lane early
Exit 32
Toward ME 111: Biddeford
4
29.3 mi into trip
|
~37m in
|
ME 111 / Alfred Street
Turn right onto ME 111 / Alfred Street
Navigation decision point
4
44.6 mi into trip
|
~58m in
Turn left
Navigation decision point
Fuel & Cost
Regular Gas
$7.20 one way
$14.39 round trip
$4.09/gal
25.4 MPG avg
16 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.50 | $7.92 | $15.84 |
| premium | $4.86 | $8.56 | $17.12 |
| diesel | $5.61 | $9.87 | $19.74 |
Estimated Tolls: $0.70
Maine Turnpike
(11.6 mi)
$0.70
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Drive Cost (one way)
Fuel
$7
Tolls
$1
Total
$8
Estimated CO2 emission: 15.6 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $5 in charging · 0 stops · 69% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 13.4 | 0 | $4.69 | $2.15 |
| Efficient EV | 11.2 | 0 | $3.91 | $1.79 |
| EV Truck/SUV | 17.9 | 0 | $6.26 | $2.86 |
Gas CO2
16 kg
EV CO2
5 kg (69% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Sanford, ME
Morning in Sanford on Sunday
Local time
6:00 AM
EDT
Current temp
51°F
Unavailable
Live forecast
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
58m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
What kind of drive is this?
This route is mostly highway, with 63% of the drive on high-speed roads like I 295 and the Maine Turnpike. You'll experience a longest stretch of 15.5 miles on I 295 before transitioning to surface roads. Expect a steady pace with fewer exits on the highway sections, giving way to more local traffic as you approach Sanford.
63% highway — fuel and pacing are the main things to plan.
15 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 15.5 mi on I 295.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on I 295 and Maine Turnpike. There are only a few real navigation decisions along the way. The trickiest moment comes around 1.5 miles in near I 295.
Driving Effort
4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 58m drive. You will face about 7 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 1.5 miles (I 295): Merge point - match speed before joining. Lane positioning matters here; at 14.3 miles (I 295): Highway fork - watch signs carefully; at 28.5 miles: Exit ramp - move to the correct lane early.
About the Cities
Starting in Yarmouth, ME
Full guide →Yarmouth is a town of 9,000 people (2020) just north of Portland in Maine.
Arriving in Sanford, ME
Full guide →Sanford is a small town is southern Maine. It includes the village of Springvale.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 58m. Total distance: 44.7 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
58m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (63%). Straightforward navigation.
Frequently Asked Questions
The longest stretch is about 15.5 miles on I 295. The full list of main roads is in the Roads section above.
Expect about $0.70 in tolls one way, starting with Maine Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
Mostly yes along the main roads, but rural stretches through ME can have sparse or no coverage. Before you leave, download offline Google Maps or Apple Maps for the route, and consider downloading music or podcasts instead of streaming. If you depend on data for navigation, keep a paper backup of the turn-by-turn directions.
The main spots that need attention: at 1.5 miles (I 295): Merge point - match speed before joining. Lane positioning matters here; at 14.3 miles (I 295): Highway fork - watch signs carefully; at 28.5 miles: Exit ramp - move to the correct lane early.
Yes. A round trip is manageable in a single day if you plan a break at Sanford, ME before heading back.
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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