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Trip from Sedalia, MO to O'Fallon, MO

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

3h 5m

Distance

157.9 mi

254 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$25

one way

EV Charging

Unknown

Best Time to Leave

Save up to 35 min
4 AM
2h 54m ★
6 AM
3h 6m
8 AM
3h 29m
10 AM
3h 14m
12 PM
3h 11m
3 PM
3h 15m
5 PM
3h 28m
8 PM
2h 59m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Sedalia, MO, MO

Sedalia, MO

Valeria Boltneva

Downtown O'Fallon, MO, MO

O'Fallon, MO

Wikimedia Commons

Trip Overview

Sedalia to O'Fallon is 157.9 miles and takes about 3h 5m via Dwight D. Eisenhower Highway and US 65, with a fuel budget near $25 and enough daylight to finish in a day. This trip stays within Missouri, moving from the Midwest region to another part of the Midwest. Expect a drive that involves frequent turns and local road sections, rather than a straightforward interstate cruise. It's a manageable one-day journey, perfect if you're looking for a relatively quick drive between these two points without a major time commitment.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

79 miles from Sedalia, MO

A natural place for your longest stop of the day , about 1h 31m into the drive .

Main Roads

Road Distance Duration
Dwight D. Eisenhower Highway 90 mi 1h 46m
U.S. Submarine Veterans' Memorial Highway 45.3 mi 48m
US 65 15.9 mi 18m
Sheriff Roger I. Wilson Memorial Highway 1.9 mi 2m
Highway Patrol Sgt. Benjamin Booth Memorial Highway 1.6 mi 1m
South Ohio Avenue 1.5 mi 4m
South Main Street 0.6 mi 1m
MO 765 0.3 mi <1m
Longest stretch: Dwight D. Eisenhower Highway — 90 mi, about 1h 46m

Turn-by-Turn Driving Directions

Step-by-step road directions between Sedalia, MO and O'Fallon, MO.

1

Start on South Ohio Avenue

1.5 mi · 4 min · South Ohio Avenue
2

Continue on MO 765

0.2 mi · 18 sec · MO 765
3

Continue on MO 765

0.1 mi · 11 sec · MO 765
Toward US 65 North: Marshall
4

Merge onto US 65

16 mi · 18 min · US 65
5

Take the exit

0.4 mi · 39 sec
Toward I 70 East: Saint Louis
6

Merge onto I 70; US 40

23 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
7

Keep slight left at fork onto I 70

22 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
8

Continue on I 70; US 40

1.8 mi · 2 min · Dwight D. Eisenhower Highway
9

Continue on I 70; US 40

1.6 mi · 1 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
10

Continue on I 70; US 40

1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
11

Continue on I 70; US 40

88 mi · 1 hr 44 min · Dwight D. Eisenhower Highway
Use the straight / slight right lanes.
12

Take the exit

0.3 mi · 43 sec
Toward MO K: O'Fallon Use the straight / slight right lanes.
13

Turn straight onto Drennen Parkway

150 ft · 3 sec · Drennen Parkway
Toward MO K: O'Fallon
14

Keep slight right at fork onto Drennen Parkway

166 ft · 5 sec · Drennen Parkway
Toward MO K: O'Fallon
15

Turn slight left

62 ft · 2 sec
Toward MO K: O'Fallon
16

Continue on South Main Street

0.6 mi · 1 min · South Main Street
17

Turn right

25 ft · 1 sec
18

Arrive at destination

Trip Plan

Given the 3h 5m duration, this trip is easily completed in a single day, so you have flexibility with your departure time. Aim to leave after morning rush hour if possible to maximize your daylight. With only one recommended stop and a relatively short drive, you can afford to be spontaneous. Keep an eye on your fuel gauge, especially when you're on the local road sections, as stations might be less frequent than on major interstates. A good tip is to check your GPS for upcoming turns regularly, as the 'turn-heavy' nature means you'll want to be prepared for frequent course changes.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 79 miles from Sedalia, MO, or about 1h 31m into the drive.
The longest continuous stretch on this route runs about 90 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 35 miles or 41m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 79 miles or 1h 31m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 30m

Traffic, exits, and arrival timing usually matter more near O'Fallon, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Sedalia, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Sedalia, MO

This is one driving day of about 157.9 miles and 3h 5m.

Your first comfortable stop window is around 35 miles from Sedalia, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D. Eisenhower Highway for about 90 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Montgomery City, MO, MO

Mid-route town

Meal stop

Montgomery City, MO

79 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Boonville, MO

Fuel and coffee

A short stop after about 35 miles helps settle the day before fatigue starts building.

Columbia, MO

Meal break

The midpoint is around 79 miles from Sedalia, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 90 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 8

5 decision points cluster between mile 17.7 and 157.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

4
17.7 mi into trip | ~23m in

Take the exit toward I 70 East: Saint Louis

Exit ramp - move to the correct lane early

Toward I 70 East: Saint Louis
4
41 mi into trip | ~48m in | I 70 / U.S. Submarine Veterans' Memorial Highway

Keep slight left at fork onto I 70 / U.S. Submarine Veterans' Memorial Highway

Highway fork - watch signs carefully

6
156.9 mi into trip | ~3h 3m in

Take the exit toward MO K: O'Fallon

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Toward MO K: O'Fallon
6
157.3 mi into trip | ~3h 3m in | Drennen Parkway

Keep slight right at fork onto Drennen Parkway toward MO K: O'Fallon

Highway fork - watch signs carefully

Toward MO K: O'Fallon
4
157.9 mi into trip | ~3h 5m in

Turn right

Navigation decision point

Fuel & Cost

Regular Gas

$24.69 one way

$49.37 round trip

$3.97/gal 25.4 MPG avg 55 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $27.10 $54.21
premium $4.89 $30.39 $60.77
diesel $5.61 $34.86 $69.72

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$25

Meals

$25–$50

Total

$50–$75

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 55.2 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $17 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 47.4 0 $16.58 $7.58
Efficient EV 39.5 0 $13.82 $6.32
EV Truck/SUV 63.2 0 $22.11 $10.11

Gas CO2

55 kg

EV CO2

18 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Sedalia, MO

Late night in Sedalia on Sunday

Local time

2:56 AM

CDT

Current temp

55°F

Unavailable

Live forecast

Destination

O'Fallon, MO

Late night in O'Fallon on Sunday

Local time

2:56 AM

CDT

Current temp

57°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

2 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

3h 5m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

This drive is characterized as a 'Turn-heavy local drive,' with only about 10% of the route on highways. You'll spend most of your time navigating US 65 and other local roads, so be prepared for a dynamic driving experience. The longest stretch without a significant change in road type is 90 miles on the Dwight D. Eisenhower Highway. This means you'll be constantly adjusting your speed and direction, making it feel more like a scenic tour through towns and countryside than a high-speed transit.

Only 10% highway — the rest is turn-by-turn surface driving.
18 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 90 mi on Dwight D. Eisenhower Highway.

How Hard Is This Drive?

5/10

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. You will hit about 8 points where you need to pay attention to lane position or signs. The trickiest moment comes around 17.7 miles in.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 157.9 miles you will encounter 8 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 17.7 miles: Exit ramp - move to the correct lane early; at 41 miles (I 70 / U.S. Submarine Veterans' Memorial Highway): Highway fork - watch signs carefully; at 156.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

About the Cities

Starting in Sedalia, MO

Full guide →

Sedalia is a city in Missouri. It was once home of famous ragtime composer Scott Joplin.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 3h 5m. Total distance: 157.9 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

3h 5m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (10%). Some complex stretches to watch for.

Scenic Drive

Mostly surface roads route profile.

Frequently Asked Questions

The longest stretch is about 90 miles on Dwight D. Eisenhower Highway. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.

The main spots that need attention: at 17.7 miles: Exit ramp - move to the correct lane early; at 41 miles (I 70 / U.S. Submarine Veterans' Memorial Highway): Highway fork - watch signs carefully; at 156.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

Possible but tiring. At 3.1 hours each way, an in-and-out day trip would put you behind the wheel for 6.2 hours — manageable with a long break at O'Fallon, MO, but most travelers stay overnight.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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