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Trip from Reading, PA to Mifflin, PA

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

2h 15m

Distance

103 mi

166 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$17

one way

EV Charging

Unknown

Best Time to Leave

Save up to 29 min
4 AM
2h 6m ★
6 AM
2h 16m
8 AM
2h 35m
10 AM
2h 22m
12 PM
2h 20m
3 PM
2h 23m
5 PM
2h 34m
8 PM
2h 10m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Mifflin, PA, PA

Mifflin, PA

Haneul Trac

Trip Overview

Reading, PA to Mifflin, PA is 103 miles and takes about 2h 15m via US 322 and I 81, with a fuel budget near $17 and enough daylight to finish in a day. This trip stays within Pennsylvania, moving from the Northeast region to the Northeast region. It's a straightforward drive, primarily on well-maintained highways, making it a practical choice for a single-day journey. Expect a consistent driving experience without significant changes in road type. This route is ideal if you're looking for an efficient way to travel between these two points without much fuss.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Midpoint

51.5 miles from Reading, PA

A natural place for your longest stop of the day , about 1h 9m into the drive .

Main Roads

Road Distance Duration
US 322 39.7 mi 49m
I 81 20.8 mi 25m
Bernville Road 14.6 mi 23m
William Penn Highway 12.2 mi 15m
78th Division Highway 7.6 mi 8m
US 222 2.4 mi 3m
West Shore Bypass 2 mi 2m
Industrial Park Road 0.7 mi 1m
Longest stretch: US 322 — 39.7 mi, about 49m

Turn-by-Turn Driving Directions

Step-by-step road directions between Reading, PA and Mifflin, PA.

1

Start on US 422 Business Alternate

0.4 mi · 40 sec · Penn Street
2

Continue on US 422 Business Alternate

0.2 mi · 19 sec · Penn Avenue
3

Take the ramp

0.2 mi · 30 sec
Toward US 422 West: Lebanon Use the straight / slight right lanes.
4

Merge onto US 422

2.0 mi · 2 min · West Shore Bypass
Use the straight / slight right lanes.
5

Continue on US 222

2.4 mi · 3 min · US 222
6

Take the exit

0.2 mi · 29 sec
Toward PA 183: Bernville Road, Strausstown Use the slight right lane.
7

Turn left onto PA 183

387 ft · 12 sec · Bernville Road
8

Continue on PA 183

10 mi · 16 min · Bernville Road
9

Continue on PA 183

4.1 mi · 7 min · Bernville Road
10

Take the ramp

0.2 mi · 30 sec
Toward I 78 West, US 22 West: Harrisburg
11

Merge onto I 78; US 22

10 mi · 11 min · William Penn Highway
12

Continue on I 78; US 22

7.6 mi · 8 min · 78th Division Highway
13

Keep slight left at fork

0.7 mi · 49 sec
Exit 1B Toward I 81 South: Harrisburg
14

Merge onto I 81

21 mi · 25 min · I 81
15

Take the exit onto US 322

0.3 mi · 27 sec · US 322
Exit 67A; 67B Toward US 22 East, PA 230 East, US 22 West, US 322 West: Harrisburg, Lewistown, State College
16

Keep slight right at fork onto US 322

39 mi · 49 min · US 322
Exit 67B Toward US 22 West, US 322 West: Lewistown, State College Use the slight right lane.
17

Take the exit

0.2 mi · 31 sec
Toward PA 75: Port Royal Use the slight right lane.
18

Keep slight right at fork

449 ft · 15 sec
Toward PA 75 South: Port Royal
19

Turn straight onto PA 75

0.7 mi · 1 min · Industrial Park Road
Use the straight lane.
20

Turn right onto SR 3002

2.0 mi · 3 min · William Penn Highway
21

Enter roundabout onto PA 35

181 ft · 3 sec · Wilson Street
22

Continue on PA 35

0.4 mi · 44 sec · Wilson Street
23

Turn right onto Parker Street

500 ft · 19 sec · Parker Street
24

Turn left onto Juniata Street

0.2 mi · 29 sec · Juniata Street
25

Turn left onto Main Street

86 ft · 3 sec · Main Street
26

Arrive at destination

Main Street

Trip Plan

Given the short 2h 15m duration, this trip offers plenty of flexibility. You could easily depart in the morning and arrive by lunchtime, leaving your afternoon open. With a fuel cost estimated at $17, you won't need extensive planning for gas stops, though it's always wise to top off before leaving Reading. The longest continuous stretch is nearly 40 miles on US 322, so plan for a quick stretch break before or after that segment if needed. Consider leaving early to avoid any potential commuter traffic around Reading.

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 51.5 miles from Reading, PA, or about 1h 9m into the drive.
The longest continuous stretch on this route runs about 39.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 23 miles or 35m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 51.5 miles or 1h 9m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 50m

Traffic, exits, and arrival timing usually matter more near Mifflin, PA than in the middle of the route.

Before You Leave

+

Open the route before leaving Reading, PA so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Reading, PA

This is one driving day of about 103 miles and 2h 15m.

Your first comfortable stop window is around 23 miles from Reading, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 322 for about 39.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Enola, PA, PA

Mid-route town

Meal stop

Enola, PA

52 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Newmanstown, PA

Fuel and coffee

A short stop after about 23 miles helps settle the day before fatigue starts building.

Harrisburg, PA

Meal break

The midpoint is around 51.5 miles from Reading, PA, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 17

5 decision points cluster between mile 0.6 and 59.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

6
0.6 mi into trip | ~0m in

Take the ramp toward US 422 West: Lebanon

Lane positioning matters here

Use the straight / slight right lanes. Toward US 422 West: Lebanon
7
5.2 mi into trip | ~7m in

Take the exit toward PA 183: Bernville Road, Strausstown

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Toward PA 183: Bernville Road, Strausstown
6
38.1 mi into trip | ~52m in

Keep slight left at fork toward I 81 South: Harrisburg

Highway fork - watch signs carefully

Exit 1B Toward I 81 South: Harrisburg
6
59.6 mi into trip | ~1h 18m in | US 322

Take the exit onto US 322 toward US 22 East, PA 230 East, US 22 West, US 322 West: Harrisburg, Lewistown, State College

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 67A; 67B Toward US 22 East, PA 230 East, US 22 West, US...
9
59.9 mi into trip | ~1h 19m in | US 322

Keep slight right at fork onto US 322 toward US 22 West, US 322 West: Lewistown, State College

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 67B Toward US 22 West, US 322 West: Lewistown, Stat...

Fuel & Cost

Regular Gas

$17.08 one way

$34.15 round trip

$4.21/gal 25.4 MPG avg 36 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.61 $18.70 $37.40
premium $4.93 $19.98 $39.95
diesel $5.61 $22.74 $45.48

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$17

Meals

$25–$50

Total

$42–$67

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 36 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $11 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 30.9 0 $10.82 $4.94
Efficient EV 25.8 0 $9.01 $4.12
EV Truck/SUV 41.2 0 $14.42 $6.59

Gas CO2

36 kg

EV CO2

12 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 16, 2026

Origin

Reading, PA

Late night in Reading on Sunday

Local time

3:42 AM

EDT

Current temp

89°F

Mostly Sunny

SW 5 to 15 mph 3% chance Live forecast

Destination

Mifflin, PA

Late night in Mifflin on Sunday

Local time

3:42 AM

EDT

Current temp

70°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

19 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 15m on the road

The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Appalachian National Scenic Trail

Appalachian National Scenic Trail

National Scenic Trail

The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...

3 mi from route ~8 min detour Free near mile 35.5
Park Closure: List of trail closures post-Hurricane Helene
Caution: Black Bears Frequenting the McAfee Knob Area in Virginia
View on nps.gov
Carlisle Federal Indian Boarding School National Monument

Carlisle Federal Indian Boarding School National Monument

National Monument

More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...

15 mi from route ~39 min detour Free near mile 71
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

This drive is predominantly highway-focused, with 61% of the journey utilizing major roadways. You'll experience a good portion of it on US 322, including a continuous stretch of 39.7 miles. While Bernville Road offers a brief local road introduction, the majority of your time will be spent on faster routes like I 81. The character remains consistent for much of the trip, favoring efficiency over winding scenic byways. It’s a drive where you can settle into a rhythm and cover ground steadily.

61% highway — fuel and pacing are the main things to plan.
26 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 39.7 mi on US 322.

How Hard Is This Drive?

10/10

This is a straightforward highway drive that stays mostly on US 322 and I 81. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.6 miles in.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 17 significant decision points across 103 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 0.6 miles: Lane positioning matters here; at 5.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 38.1 miles: Highway fork - watch signs carefully.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Reading, PA and Mifflin, PA, road signs point toward Strausstown, Lewistown and State College.

Strausstown

5.2 mi in | ~7m

Lewistown

59.6 mi in | ~1h 18m | via US 322

State College

59.6 mi in | ~1h 18m | via US 322

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 2h 15m. Total distance: 103 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

2h 15m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (61%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 39.7 miles on US 322. The full list of main roads is in the Roads section above.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Mifflin, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 0.6 miles: Lane positioning matters here; at 5.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 38.1 miles: Highway fork - watch signs carefully.

Yes — Appalachian National Scenic Trail and Carlisle Federal Indian Boarding School National Monument. See the National Parks section for detour distances and tips on detours.

Yes. A round trip is manageable in a single day if you plan a break at Mifflin, PA before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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