Origin
Mifflin, PA
Late night in Mifflin on Tuesday
Local time
5:14 AM
EDT
Current temp
70°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
3h 59m
Distance
179.7 mi
289 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$30
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Mifflin, PA
Haneul Trac
Pittsburgh, PA
Wikimedia Commons
This 179.7-mile journey from Mifflin to Pittsburgh, Pennsylvania, is easily manageable as a single-day trip, taking just under 4 hours to complete. You'll primarily navigate along the William Penn Highway and I-99, with a portion on US 22, offering a mixed driving experience. With an estimated fuel cost of around $30, this route is quite budget-friendly for a day excursion. The drive will take you across Pennsylvania, maintaining its Northeastern region feel throughout. It's a straightforward drive that gets you from point A to point B without extensive planning, making it ideal for a spontaneous road trip.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
89.8 miles from Mifflin, PA
A natural place for your longest stop of the day , about 1h 52m into the drive .
| Road | Distance | Duration |
|---|---|---|
| William Penn Highway | 63.5 mi | 1h 29m |
| I 99 | 33.8 mi | 36m |
| US 22 | 31.2 mi | 40m |
| Mount Nittany Expressway | 17.5 mi | 21m |
| Penn-Lincoln Parkway East | 13.5 mi | 18m |
| Admiral Peary Highway | 13.4 mi | 19m |
| Boal Avenue | 2.6 mi | 4m |
| Wilson Street | 0.4 mi | <1m |
Step-by-step road directions between Mifflin, PA and Pittsburgh, PA.
Start on Main Street
Turn left onto Tuscarora Street
Turn right onto Juniata Street
Turn right onto Parker Street
Turn left onto PA 35
Enter roundabout onto PA 35; SR 3002
Continue on PA 35; SR 3002
Continue on PA 35; SR 3002
Continue on SR 3002
Turn right onto SR 3002
Take the ramp
Merge onto US 22; US 322
Keep slight left at fork onto US 22; US 322
Continue on US 322; PA 144 Truck
Continue on US 322; PA 144 Truck
Keep slight left at fork onto I 99; US 220
Take the exit
Continue on this road
Continue on US 22
Continue on US 22
Continue on US 22
Keep slight right at fork onto I 376; US 22
Take the exit
Turn straight onto Second Avenue
At end of road, turn right onto Ross Street
Turn left onto Fifth Avenue
Turn right onto Grant Street
Arrive at destination
Given the 3-hour and 59-minute duration, departing in the morning will allow you ample time to reach Pittsburgh without feeling rushed. With only one recommended stop, you have flexibility in how you pace yourself. Keep an eye on your fuel levels, as the estimated cost is $30, and plan your refueling accordingly. A practical tip for this route is to be aware of the transition from US 22 to I-99; follow signs carefully to ensure a smooth merge. This drive is well-suited for a single day, so you can enjoy the flexibility of leaving when it's most convenient for you.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 40 miles or 55m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 89.8 miles or 1h 52m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 12m
Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.
Open the route before leaving Mifflin, PA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Mifflin, PA
This is one driving day of about 179.7 miles and 3h 59m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
90 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 40 miles helps settle the day before fatigue starts building.
The midpoint is around 89.8 miles from Mifflin, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before William Penn Highway if your tank is already low. That segment runs about 63.5 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 10.9 and 179.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Keep slight left at fork onto US 22; US 322 toward US 22 West, US 322 West: Mount Union, State College
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward Second Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Turn right onto Grant Street
Lane positioning matters here
Regular Gas
$29.79 one way
$59.58 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $32.63 | $65.26 |
| premium | $4.93 | $34.85 | $69.70 |
| diesel | $5.61 | $39.68 | $79.35 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 62.9 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $19 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 53.9 | 0 | $18.87 | $8.63 |
| Efficient EV | 44.9 | 0 | $15.72 | $7.19 |
| EV Truck/SUV | 71.9 | 0 | $25.16 | $11.50 |
Gas CO2
63 kg
EV CO2
21 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Mifflin on Tuesday
Local time
5:14 AM
EDT
Current temp
70°F
Unavailable
Destination
Late night in Pittsburgh on Tuesday
Local time
5:14 AM
EDT
Current temp
69°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Expect a varied drive on this route, with 53% of it being highway driving. You'll experience stretches of faster-paced highway alongside more local road sections, creating a "Mixed drive" profile. The longest uninterrupted stretch you'll encounter is 63.5 miles on the William Penn Highway, offering a good period of consistent travel. As you progress, the road character will shift, transitioning from potentially more rural or suburban segments to the approach of a major metropolitan area.
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 10.9 miles in near US 22; US 322.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 15 significant decision points across 179.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 10.9 miles (US 22; US 322): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 55.6 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 165.4 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Mifflin, PA and Pittsburgh, PA, road signs point toward State College, Altoona and Hollidaysburg.
State College
Altoona
Hollidaysburg
Founded 1758
The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.
Top landmarks
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 3h 59m. Total distance: 179.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 59m drive, comfortable solo distance.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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