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Trip from Mifflin, PA to Pittsburgh, PA

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards

Drive Time

3h 59m

Distance

179.7 mi

289 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$30

one way

EV Charging

Unknown

Best Time to Leave

Save up to 39 min
4 AM
3h 47m ★
6 AM
4h 0m
8 AM
4h 26m
10 AM
4h 9m
12 PM
4h 6m
3 PM
4h 10m
5 PM
4h 24m
8 PM
3h 52m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Mifflin, PA, PA

Mifflin, PA

Haneul Trac

city and county seat in Allegheny County, Pennsylvania, United States

Pittsburgh, PA

Wikimedia Commons

Trip Overview

This 179.7-mile journey from Mifflin to Pittsburgh, Pennsylvania, is easily manageable as a single-day trip, taking just under 4 hours to complete. You'll primarily navigate along the William Penn Highway and I-99, with a portion on US 22, offering a mixed driving experience. With an estimated fuel cost of around $30, this route is quite budget-friendly for a day excursion. The drive will take you across Pennsylvania, maintaining its Northeastern region feel throughout. It's a straightforward drive that gets you from point A to point B without extensive planning, making it ideal for a spontaneous road trip.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

89.8 miles from Mifflin, PA

A natural place for your longest stop of the day , about 1h 52m into the drive .

Main Roads

Road Distance Duration
William Penn Highway 63.5 mi 1h 29m
I 99 33.8 mi 36m
US 22 31.2 mi 40m
Mount Nittany Expressway 17.5 mi 21m
Penn-Lincoln Parkway East 13.5 mi 18m
Admiral Peary Highway 13.4 mi 19m
Boal Avenue 2.6 mi 4m
Wilson Street 0.4 mi <1m
Longest stretch: William Penn Highway — 63.5 mi, about 1h 29m

Turn-by-Turn Driving Directions

Step-by-step road directions between Mifflin, PA and Pittsburgh, PA.

1

Start on Main Street

0.1 mi · 29 sec · Main Street
2

Turn left onto Tuscarora Street

375 ft · 18 sec · Tuscarora Street
3

Turn right onto Juniata Street

0.1 mi · 18 sec · Juniata Street
4

Turn right onto Parker Street

500 ft · 19 sec · Parker Street
5

Turn left onto PA 35

0.4 mi · 42 sec · Wilson Street
6

Enter roundabout onto PA 35; SR 3002

197 ft · 3 sec · William Penn Highway
7

Continue on PA 35; SR 3002

0.2 mi · 24 sec · William Penn Highway
8

Continue on PA 35; SR 3002

0.3 mi · 33 sec · South Main Street
9

Continue on SR 3002

2.0 mi · 3 min · William Penn Highway
10

Turn right onto SR 3002

0.4 mi · 44 sec · Arch Rock Road
11

Take the ramp

0.5 mi · 1 min
Toward US 22 West, US 322 West: Lewistown
12

Merge onto US 22; US 322

6.7 mi · 7 min · US 22; US 322
13

Keep slight left at fork onto US 22; US 322

24 mi · 32 min · US 22; US 322
Toward US 22 West, US 322 West: Mount Union, State College
14

Continue on US 322; PA 144 Truck

2.6 mi · 4 min · Boal Avenue
Use the straight / right lanes.
15

Continue on US 322; PA 144 Truck

18 mi · 21 min · Mount Nittany Expressway
16

Keep slight left at fork onto I 99; US 220

34 mi · 36 min · I 99; US 220
Toward I 99 South, US 220 South: Port Matilda, Altoona
17

Take the exit

0.8 mi · 1 min
Toward US 22: Ebensburg, Hollidaysburg
18

Continue on this road

0.5 mi · 43 sec · this road
19

Continue on US 22

16 mi · 19 min · William Penn Highway
20

Continue on US 22

13 mi · 19 min · Admiral Peary Highway
Use the straight lane.
21

Continue on US 22

45 mi · 1 hr 6 min · William Penn Highway
Use the straight / right lanes.
22

Keep slight right at fork onto I 376; US 22

13 mi · 18 min · Penn-Lincoln Parkway East
Toward I 376 West, US 22 West: Pittsburgh Use the slight left lane.
23

Take the exit

0.2 mi · 38 sec
Exit 71B Toward Second Avenue Use the straight / slight right lanes.
24

Turn straight onto Second Avenue

0.3 mi · 41 sec · Second Avenue
25

At end of road, turn right onto Ross Street

0.2 mi · 32 sec · Ross Street
26

Turn left onto Fifth Avenue

352 ft · 10 sec · Fifth Avenue
27

Turn right onto Grant Street

513 ft · 21 sec · Grant Street
Use the right lane.
28

Arrive at destination

Grant Street

Trip Plan

Given the 3-hour and 59-minute duration, departing in the morning will allow you ample time to reach Pittsburgh without feeling rushed. With only one recommended stop, you have flexibility in how you pace yourself. Keep an eye on your fuel levels, as the estimated cost is $30, and plan your refueling accordingly. A practical tip for this route is to be aware of the transition from US 22 to I-99; follow signs carefully to ensure a smooth merge. This drive is well-suited for a single day, so you can enjoy the flexibility of leaving when it's most convenient for you.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 89.8 miles from Mifflin, PA, or about 1h 52m into the drive.
The longest continuous stretch on this route runs about 63.5 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 40 miles or 55m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 89.8 miles or 1h 52m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 12m

Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.

Before You Leave

+

Open the route before leaving Mifflin, PA so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Mifflin, PA

This is one driving day of about 179.7 miles and 3h 59m.

Your first comfortable stop window is around 40 miles from Mifflin, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on William Penn Highway for about 63.5 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Hollidaysburg, PA, PA

Mid-route town

Meal stop

Hollidaysburg, PA

90 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

State College, PA

Fuel and coffee

A short stop after about 40 miles helps settle the day before fatigue starts building.

Hollidaysburg, PA

Meal break

The midpoint is around 89.8 miles from Mifflin, PA, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before William Penn Highway if your tank is already low. That segment runs about 63.5 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 15

5 decision points cluster between mile 10.9 and 179.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

6
10.9 mi into trip | ~16m in | US 22; US 322

Keep slight left at fork onto US 22; US 322 toward US 22 West, US 322 West: Mount Union, State College

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward US 22 West, US 322 West: Mount Union, St...
6
55.6 mi into trip | ~1h 14m in | I 99; US 220

Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 99 South, US 220 South: Port Matilda,...
8
165.4 mi into trip | ~3h 38m in | I 376; US 22 / Penn-Lincoln Parkway East

Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Toward I 376 West, US 22 West: Pittsburgh
7
178.9 mi into trip | ~3h 57m in

Take the exit toward Second Avenue

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 71B Toward Second Avenue
7
179.6 mi into trip | ~3h 59m in | Grant Street

Turn right onto Grant Street

Lane positioning matters here

Use the right lane.

Fuel & Cost

Regular Gas

$29.79 one way

$59.58 round trip

$4.21/gal 25.4 MPG avg 63 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.61 $32.63 $65.26
premium $4.93 $34.85 $69.70
diesel $5.61 $39.68 $79.35

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$30

Meals

$25–$50

Total

$55–$80

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 62.9 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $19 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 53.9 0 $18.87 $8.63
Efficient EV 44.9 0 $15.72 $7.19
EV Truck/SUV 71.9 0 $25.16 $11.50

Gas CO2

63 kg

EV CO2

21 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 19, 2026

Origin

Mifflin, PA

Late night in Mifflin on Tuesday

Local time

5:14 AM

EDT

Current temp

70°F

Unavailable

Live forecast

Destination

Pittsburgh, PA

Late night in Pittsburgh on Tuesday

Local time

5:14 AM

EDT

Current temp

69°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

1 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

3h 59m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a varied drive on this route, with 53% of it being highway driving. You'll experience stretches of faster-paced highway alongside more local road sections, creating a "Mixed drive" profile. The longest uninterrupted stretch you'll encounter is 63.5 miles on the William Penn Highway, offering a good period of consistent travel. As you progress, the road character will shift, transitioning from potentially more rural or suburban segments to the approach of a major metropolitan area.

53% highway, the rest on surface roads — varied driving throughout.
28 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 63.5 mi on William Penn Highway.

How Hard Is This Drive?

7/10

This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 10.9 miles in near US 22; US 322.

Driving Effort 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 15 significant decision points across 179.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 10.9 miles (US 22; US 322): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 55.6 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 165.4 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Mifflin, PA and Pittsburgh, PA, road signs point toward State College, Altoona and Hollidaysburg.

State College

10.9 mi in | ~16m | via US 22; US 322

Altoona

55.6 mi in | ~1h 14m | via I 99; US 220

Hollidaysburg

89.4 mi in | ~1h 51m

About the Cities

Arriving in Pittsburgh, PA

Full guide →

Founded 1758

The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.

Top landmarks

  • Carnegie Museum of Natural History — natural history museum in Pittsburgh, Pennsylvania, United States
  • Allegheny Observatory — historic observatory of the University of Pittsburgh
  • Carnegie Museum of Art — museum in Pittsburgh, Pennsylvania

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 3h 59m. Total distance: 179.7 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

3h 59m drive, comfortable solo distance.

Frequently Asked Questions

The longest stretch is about 63.5 miles on William Penn Highway. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Pittsburgh, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 10.9 miles (US 22; US 322): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 55.6 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 165.4 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Possible but tiring. At 4.0 hours each way, an in-and-out day trip would put you behind the wheel for 8.0 hours — manageable with a long break at Pittsburgh, PA, but most travelers stay overnight.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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