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Trip from Mosheim, TN to Knoxville, TN

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

1h 11m

Distance

62.7 mi

101 km

Drive Score

7/10

Good drive

Same Day?

Yes, doable

Fuel Cost

$10

one way

EV Charging

Unknown

Best Time to Leave

Save up to 16 min
4 AM
1h 6m ★
6 AM
1h 11m
8 AM
1h 22m
10 AM
1h 15m
12 PM
1h 14m
3 PM
1h 16m
5 PM
1h 22m
8 PM
1h 8m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Mosheim, TN, TN

Mosheim, TN

Kelly

city and county seat of Knox County, State of Tennessee, United States

Knoxville, TN

Wikimedia Commons

Trip Overview

This straightforward 62.7-mile drive from Mosheim, TN to Knoxville, TN takes about 1 hour and 11 minutes and is perfect for a single-day trip. With 87% of the journey on highways, you'll primarily be on I-40 and I-81, with a brief stint on West Andrew Johnson Highway. The estimated fuel cost is a budget-friendly $10, making it an economical option. This route stays within the Southeast region, offering a familiar landscape for those traveling within Tennessee. It's a direct and efficient way to get from point A to point B, ideal for a quick transfer or a short excursion.

Main Roads

Road Distance Duration
I 40 31.5 mi 34m
I 81 22.7 mi 24m
West Andrew Johnson Highway 5.7 mi 6m
James White Parkway 0.4 mi <1m
Cumberland Avenue 0.3 mi <1m
Neyland Drive 0.1 mi <1m
Henley Street 0.1 mi <1m
Railroad Street <0.1 mi <1m
Longest stretch: I 40 — 31.5 mi, about 34m

Turn-by-Turn Driving Directions

Step-by-step road directions between Mosheim, TN and Knoxville, TN.

1

Start on Main Street

135 ft · 11 sec · Main Street
2

Turn left onto Railroad Street

357 ft · 15 sec · Railroad Street
3

Take the ramp

117 ft · 3 sec
4

Merge onto US 11E

5.7 mi · 6 min · West Andrew Johnson Highway
5

Turn left

0.3 mi · 39 sec
6

Merge onto I 81

22 mi · 23 min · I 81
7

Continue on I 81

0.7 mi · 45 sec · I 81
Exit 1B Toward I 40 West: Knoxville
8

Merge onto I 40

32 mi · 34 min · I 40
Use the straight / slight right lanes.
9

Take the exit

0.3 mi · 26 sec
Exit 388A; 389 Toward SR 158 West: Downtown, University of Tennessee Use the slight right lane.
10

Keep slight left at fork

0.9 mi · 2 min
Toward TN 158 West, South US 441: James White Parkway, Downtown, University of Tennessee
11

Continue on TN 158

0.4 mi · 23 sec · James White Parkway
12

Keep slight right at fork onto TN 158

0.1 mi · 14 sec · Neyland Drive
Toward TN 158 West: Neyland Drive, University of Tennessee
13

Take the exit

0.2 mi · 31 sec
Toward Downtown, Cumerland Avenue
14

Continue on Cumberland Avenue

0.3 mi · 37 sec · Cumberland Avenue
15

Turn left onto US 441

393 ft · 16 sec · Henley Street
16

Continue on US 441

255 ft · 11 sec · Henley Street
17

Arrive at destination

US 441

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

town in Jefferson County, Tennessee, United States

Mid-route town

Meal stop

Dandridge, TN

31 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Dandridge, TN to Knoxville, TN

32.2 mi · 39m

Pacing Suggestions

East Ridge, TN

Fuel and coffee

A short stop after about 14 miles helps settle the day before fatigue starts building.

Dandridge, TN

Meal break

The midpoint is around 31.4 miles from Mosheim, TN, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 10

5 decision points cluster between mile 0 and 62 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

5
0 mi into trip | ~0m in | Railroad Street

Turn left onto Railroad Street

Navigation decision point

8
60.3 mi into trip | ~1h 6m in

Take the exit toward SR 158 West: Downtown, University of Tennessee

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 388A; 389 Toward SR 158 West: Downtown, University of Ten...
6
60.6 mi into trip | ~1h 6m in

Keep slight left at fork toward TN 158 West, South US 441: James White Parkway, Downtown, University of Tennessee

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward TN 158 West, South US 441: James White P...
6
61.9 mi into trip | ~1h 9m in | TN 158 / Neyland Drive

Keep slight right at fork onto TN 158 / Neyland Drive toward TN 158 West: Neyland Drive, University of Tennessee

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward TN 158 West: Neyland Drive, University o...
6
62 mi into trip | ~1h 9m in

Take the exit toward Downtown, Cumerland Avenue

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Toward Downtown, Cumerland Avenue

Fuel & Cost

Regular Gas

$9.80 one way

$19.60 round trip

$3.97/gal 25.4 MPG avg 22 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $10.76 $21.53
premium $4.89 $12.07 $24.13
diesel $5.61 $13.84 $27.69

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$10

Estimated CO2 emission: 21.9 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $7 in charging · 0 stops · 68% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 18.8 0 $6.58 $3.01
Efficient EV 15.7 0 $5.49 $2.51
EV Truck/SUV 25.1 0 $8.78 $4.01

Gas CO2

22 kg

EV CO2

7 kg (68% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Mosheim, TN

Morning in Mosheim on Sunday

Local time

6:01 AM

EDT

Current temp

46°F

Unavailable

Live forecast

Destination

Knoxville, TN

Morning in Knoxville on Sunday

Local time

6:01 AM

EDT

Current temp

74°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

28 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

1h 11m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a highway-focused drive for the majority of this trip, with 87% of the route utilizing major interstates like I-40 and I-81. You'll encounter an uninterrupted stretch of 31.5 miles on I-40, offering a consistent pace. The inclusion of West Andrew Johnson Highway provides a slight variation from the pure interstate experience. This drive is characterized by its efficiency and speed, rather than winding scenic byways, making it a practical choice for covering ground.

87% highway — fuel and pacing are the main things to plan.
17 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 31.5 mi on I 40.

How Hard Is This Drive?

6/10

This is a straightforward highway drive that stays mostly on I 40 and I 81. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near Railroad Street.

Driving Effort 6/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 62.7 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: near the start (Railroad Street): Navigation decision point; at 60.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 60.6 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.

About the Cities

Arriving in Knoxville, TN

Full guide →

Knoxville, in Knox County, is the third-largest city in Tennessee. It is the home of the University of Tennessee's primary campus (UTK) and site of the 1982 World's Fair.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 1h 11m. Total distance: 62.7 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

1h 11m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (87%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 31.5 miles on I 40. The full list of main roads is in the Roads section above.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Knoxville, TN before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: near the start (Railroad Street): Navigation decision point; at 60.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 60.6 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.

Yes — Great Smoky Mountains National Park. See the National Parks section for detour distances and tips on detours.

Yes. A round trip is manageable in a single day if you plan a break at Knoxville, TN before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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