Origin
Knoxville, TN
Morning in Knoxville on Sunday
Local time
7:57 AM
EDT
Current temp
74°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
4h 3m
Distance
221.2 mi
356 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$35
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Knoxville, TN
Wikimedia Commons
Columbia, TN
Wikimedia Commons
This 221.2-mile drive from Knoxville, TN, to Columbia, TN, is easily manageable as a single-day trip, taking approximately 4 hours and 3 minutes to complete. With 94% of the journey on highways, you'll spend most of your time on major interstates like I-40 and I-65. The estimated fuel cost for this Southeast to Southeast journey is around $35, making it a budget-friendly option. This route offers a straightforward, highway-focused experience, perfect for those prioritizing efficiency and covering ground quickly. Given its relatively short duration, you can depart at your leisure and still arrive with plenty of daylight.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
110.6 miles from Knoxville, TN
A natural place for your longest stop of the day , about 2h 1m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 40 | 151 mi | 2h 44m |
| Tennessee National Guard Parkway | 44.6 mi | 47m |
| I 65 | 11.5 mi | 12m |
| Bear Creek Pike | 7.1 mi | 8m |
| Nashville Highway | 1.4 mi | 2m |
| Western Avenue | 0.7 mi | 1m |
| North Garden Street | 0.5 mi | <1m |
| Ailor Avenue | 0.4 mi | <1m |
Step-by-step road directions between Knoxville, TN and Columbia, TN.
Start on US 441
Continue on US 441
Turn slight left onto SR 62
Turn left onto Ailor Avenue
Take the ramp
Merge onto I 40
Keep slight right at fork onto I 40
Take the exit
Continue on I 840
Take the exit
Keep slight left at fork
Merge onto I 65
Take the exit
Keep slight right at fork
Turn right onto US 412
Turn left onto US 31; US 412 Business
Continue on US 31; US 412 Business
Turn left onto West 7th Street
Arrive at destination
For this 4-hour, 3-minute drive, departing Knoxville in the morning is ideal to maximize your time in Columbia. With only one recommended stop, you have flexibility in pacing. Plan your fuel stops strategically, as the longest stretch is 151 miles on I-40, so ensure you're topped off before that segment. The $35 fuel cost is a good estimate, but always factor in potential price fluctuations. Given the manageable distance, you won't need to split this drive, but consider a brief stop along I-40 for a stretch and to break up the longest driving segment.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 55m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 110.6 miles or 2h 1m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 17m
Traffic, exits, and arrival timing usually matter more near Columbia, TN than in the middle of the route.
Open the route before leaving Knoxville, TN so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Knoxville, TN
This is one driving day of about 221.2 miles and 4h 3m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
111 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 49 miles helps settle the day before fatigue starts building.
The midpoint is around 110.6 miles from Knoxville, TN, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 40 if your tank is already low. That segment runs about 151 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 20.1 and 212.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Keep slight right at fork onto I 40 toward Nashville
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward I 840 West: Memphis, Murfreesboro
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward I 65: Nashville, Huntsville
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward I 65 South: Huntsville
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight right at fork toward 412: Columbia
Highway fork - watch signs carefully
Regular Gas
$34.58 one way
$69.16 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $37.97 | $75.94 |
| premium | $4.89 | $42.57 | $85.14 |
| diesel | $5.61 | $48.84 | $97.68 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$35
Meals
$25–$50
Total
$60–$85
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 77.4 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 66.4 | 0 | $23.23 | $10.62 |
| Efficient EV | 55.3 | 0 | $19.35 | $8.85 |
| EV Truck/SUV | 88.5 | 1 | $30.97 | $14.16 |
Gas CO2
77 kg
EV CO2
26 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in Knoxville on Sunday
Local time
7:57 AM
EDT
Current temp
74°F
Unavailable
Destination
Morning in Columbia on Sunday
Local time
6:57 AM
CDT
Current temp
84°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Battlefield
The Battle of Stones River began on the last day of 1862 and became one of the bloodiest conflicts of the Civil War. The battle produced important military and political gains for the Union, and it ch...
Park data from the National Park Service API. Alerts update every 2 hours.
Expect a predominantly highway-focused drive, with 94% of the route utilizing major interstates. You'll encounter a long, uninterrupted stretch of 151 miles on I-40, which sets a consistent pace for a significant portion of the trip. The Tennessee National Guard Parkway offers a brief alternative before merging onto I-65. This drive is characterized by its efficiency, allowing you to cover distance smoothly on well-maintained roadways. The nature of the road remains largely consistent, emphasizing speed and direct travel.
This is a straightforward highway drive that stays mostly on I 40 and Tennessee National Guard Parkway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 20.1 miles in near I 40.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 13 significant decision points across 221.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 20.1 miles (I 40): Highway fork - watch signs carefully. Lane positioning matters here; at 152.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 198.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Knoxville, TN and Columbia, TN, road signs point toward Nashville, Murfreesboro and Huntsville.
Nashville
Murfreesboro
Huntsville
Knoxville, in Knox County, is the third-largest city in Tennessee. It is the home of the University of Tennessee's primary campus (UTK) and site of the 1982 World's Fair.
Columbia is the county seat of Maury County in Central Tennessee, and is 50 miles south of Nashville. It is home to an estimated 38,224 people and hosts a mule day festival the first weekend of April every year. It is more famously known for being the hometown of the 11th President of the United States, James K. Polk. In addition, numerous antebellum homes are located around the city including Ripavilla, the Atheneum, Elm Springs, Rattle and Snap, and Hamilton Place to name a few. It is a city rich in history and culture endearingly known by its locals as "The Dimple of the Universe". It's safe to say the South has had its moments of racism and racial unrest, but Columbia seems to take it to a higher level. From indiscriminate lynchings as though they were pastimes to a race riot in 1946, racism has seemed pretty systemic here.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 4h 3m. Total distance: 221.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 3m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (94%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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