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Trip from Greenville, SC to Anderson, SC

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards

Drive Time

45m

Distance

29.8 mi

48 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$5

one way

EV Charging

Unknown

Best Time to Leave

Save up to 11 min
4 AM
0h 42m ★
6 AM
0h 45m
8 AM
0h 53m
10 AM
0h 48m
12 PM
0h 47m
3 PM
0h 49m
5 PM
0h 53m
8 PM
0h 43m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Anderson, SC, SC

Anderson, SC

Junior Bastos

Trip Overview

Traveling between Greenville and Anderson, South Carolina, is a quick 30.7-mile journey that typically takes about 40 minutes behind the wheel. Because the duration is so brief, this trip is perfectly suited for a single-day outing or a simple commute. You will navigate a combination of Mills Avenue, I-85 South, and SC-81 to complete the connection. With a modest fuel budget of approximately $5, this route is an economical choice for those looking to traverse the Southeast region efficiently. Whether you are heading out for business or a change of scenery, the simplicity of this path makes it a stress-free experience.

Main Roads

Road Distance Duration
US 29 14.7 mi 18m
Highway 81 North 5 mi 8m
Mills Avenue 3.4 mi 5m
East Greenville Street 2.9 mi 5m
North Church Street 1.5 mi 3m
State Highway 81 1.1 mi 1m
North Fant Street 0.6 mi 1m
East Whitner Street 0.3 mi <1m
Longest stretch: US 29 — 14.7 mi, about 18m

Turn-by-Turn Driving Directions

Step-by-step road directions between Greenville, SC and Anderson, SC.

1

Start on US 29

1.5 mi · 3 min · North Church Street
2

Continue on US 29

3.4 mi · 5 min · Mills Avenue
Use the straight / right lanes.
3

Take the exit onto US 29

15 mi · 18 min · US 29
Exit 14B Toward I 85 South, US 29 South: Atlanta Use the slight right lane.
4

Take the exit

0.2 mi · 25 sec
Exit 27 Toward SC 81: Anderson Use the straight / slight right lanes.
5

Keep slight left at fork

194 ft · 10 sec
6

Turn left onto SC 81

0.3 mi · 32 sec · Highway 81 North
7

Continue on SC 81

1.1 mi · 1 min · State Highway 81
8

Continue on SC 81

4.8 mi · 7 min · Highway 81 North
9

Continue on East Greenville Street

2.9 mi · 5 min · East Greenville Street
10

Turn left onto North Fant Street

0.6 mi · 1 min · North Fant Street
11

Turn right onto East Whitner Street

0.3 mi · 47 sec · East Whitner Street
12

Arrive at destination

East Whitner Street

Heads-up: tricky spots

5 of 6

5 decision points cluster between mile 4.9 and 28.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

8
4.9 mi into trip | ~8m in | US 29

Take the exit onto US 29 toward I 85 South, US 29 South: Atlanta

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 14B Toward I 85 South, US 29 South: Atlanta
7
19.6 mi into trip | ~27m in

Take the exit toward SC 81: Anderson

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 27 Toward SC 81: Anderson
5
19.8 mi into trip | ~27m in

Keep slight left at fork

Highway fork - watch signs carefully

4
19.9 mi into trip | ~27m in | SC 81 / Highway 81 North

Turn left onto SC 81 / Highway 81 North

Navigation decision point

3
28.9 mi into trip | ~43m in | North Fant Street

Turn left onto North Fant Street

Navigation decision point

Fuel & Cost

Regular Gas

$4.66 one way

$9.32 round trip

$3.97/gal 25.4 MPG avg 10 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $5.10 $10.19
premium $4.70 $5.52 $11.03
diesel $5.61 $6.58 $13.16

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$5

Estimated CO2 emission: 10.4 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $3 in charging · 0 stops · 70% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 8.9 0 $3.13 $1.43
Efficient EV 7.5 0 $2.61 $1.19
EV Truck/SUV 11.9 0 $4.17 $1.91

Gas CO2

10 kg

EV CO2

3 kg (70% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 20, 2026

Origin

Greenville, SC

Late night in Greenville on Tuesday

Local time

4:52 AM

EDT

Current temp

80°F

Unavailable

Live forecast

Destination

Anderson, SC

Late night in Anderson on Tuesday

Local time

4:52 AM

EDT

Current temp

59°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

21 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

45m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a turn-heavy, local driving experience that leans more toward technical maneuvering than a monotonous interstate grind. While you will utilize I-85 South, the route relies heavily on local roads, meaning the highway percentage is essentially negligible. You won't face any significant long, uninterrupted stretches, as the road requires your constant attention through various turns and transitions. The character of the drive shifts from the urban feel of Greenville to the local roadways leading into Anderson. It is a practical, hands-on drive that demands you stay engaged with your navigation as you transition between these two South Carolina cities.

70% highway — fuel and pacing are the main things to plan.
12 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 14.7 mi on US 29.

How Hard Is This Drive?

5/10

This is a straightforward highway drive that stays mostly on US 29 and Highway 81 North. You will hit about 6 points where you need to pay attention to lane position or signs. The trickiest moment comes around 4.9 miles in near US 29.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 29.8 miles you will encounter 6 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 4.9 miles (US 29): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 19.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 19.8 miles: Highway fork - watch signs carefully.

About the Cities

Starting in Greenville, SC

Full guide →

Founded 1831

Greenville has been described as Athens, Georgia for adults. It is the county seat and largest city of Greenville County, South Carolina, United States. Greenville is also the center of the largest metropolitan area of South Carolina. Columbia, Charleston, and North Charleston have more people, but the urban area around Greenville is larger. With its historic homes and modern office towers, Greenville is said to be where "Old South" meets "New South".

Top landmarks

  • Reedy River Falls Historic Park and Greenway — Park in Greenville, South Carolina, U.S.A.
  • Poinsett Hotel — Historic hotel in Greenville, South Carolina
  • Greenville County Museum of Art — art museum in Greenville, South Carolina

Arriving in Anderson, SC

Full guide →

Anderson is a county and city in the Upcountry of South Carolina. The city of Anderson had a population of 27,545 in 2016 with an urban area population of 75,702. Anderson County had a population of 194,692 in 2016. The city of Anderson serves as one of the three primary cities in the Upcountry of South Carolina, the others being Spartanburg and Greenville.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 45m. Total distance: 29.8 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

45m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (70%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 14.7 miles on US 29. The full list of main roads is in the Roads section above.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: at 4.9 miles (US 29): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 19.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 19.8 miles: Highway fork - watch signs carefully.

Yes. A round trip is manageable in a single day if you plan a break at Anderson, SC before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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Explore More

Return Trip

Anderson, SC to Greenville, SC

Plan the drive back the other way.

29.8 mi 45m

Explore more options from Greenville, SC or browse trips ending in Anderson, SC.

Looking for more statewide routes? Browse SC road trips.