Skip to main content

Greenville, SC Road Trips

With 29 routes heading out and 54 heading in, Greenville, SC works well as a launching point in the Southeast. Most drives stay under 104 miles, making this area well-suited for day trips and weekend getaways. Most routes from Greenville, SC head east, giving the route network a clear directional lean.

Greenville, SC

Trip Routes

83

Longest Drive

259.8 mi

North Myrtle Beach, SC

Quickest Drive

13m

Walden Pond, SC

Plan Around Greenville, SC

Trips from Greenville, SC

Driving from Greenville, SC

The typical drive from Greenville, SC covers about 104 miles and takes around 2h 8m. The majority of routes are short drives — quick enough to finish before lunch and be back for dinner. The longest mapped route runs 260 miles (5h 4m), while the shortest is just 7 miles.

Popular Destinations

Top road trip destinations from Greenville, SC are North Myrtle Beach, SC (259.8 mi, 5h 4m), Conway, SC (233.4 mi, 4h 34m), Sullivans Island, SC (219.3 mi, 4h 8m), Yemassee, SC (208.3 mi, 3h 51m), and Allendale, SC (175.3 mi, 3h 22m). Most destinations stay within the same state, perfect for exploring the local region thoroughly.

Planning & Costs

Regular gas in SC currently averages around $3.96 per gallon. For the typical 104-mile trip from Greenville, SC, budget about $16 in fuel one way, assuming 25 MPG. Longer hauls and premium fuel will cost proportionally more.

With an average drive under three hours, you have plenty of flexibility — leave whenever it suits you. Routes tend to go east, so afternoon departures put the sun at your back on the return leg.

Frequently Asked Questions

There are 29 mapped routes leaving Greenville, SC and 54 routes heading into Greenville, SC, covering 83 total connections. Distances range from 7 to 260 miles.

The longest mapped route from Greenville, SC covers 260 miles and takes approximately 5h 4m. Shorter options start at just 7 miles.

The average route from Greenville, SC runs about 104 miles with a drive time of roughly 2h 8m. This includes both short day trips and longer multi-day drives.

At current gas prices (about $3.96/gallon for regular), the average 104-mile trip from Greenville, SC costs roughly $16 in fuel one way, based on 25 MPG. Your actual cost depends on your vehicle's efficiency.

The most popular road trip destinations from Greenville, SC include North Myrtle Beach, SC, Conway, SC, Sullivans Island, SC and Yemassee, SC. Each route page has detailed drive times, fuel estimates, stop suggestions, and turn-by-turn directions.

Greenville, SC by the Numbers

Recent demographic snapshot from the US Census Bureau's American Community Survey.

Population

71,755

Median Income

$68,460

Median Home Value

$453,300

Median Age

34.8

Source: US Census Bureau ACS 5-year (public domain). See our methodology for details.

Traveler Guide to Greenville, SC

Greenville has been described as Athens, Georgia for adults. It is the county seat and largest city of Greenville County, South Carolina, United States. Greenville is also the center of the largest metropolitan area of South Carolina. Columbia, Charleston, and North Charleston have more people, but the urban area around Greenville is larger. With its historic homes and modern office towers, Greenville is said to be where "Old South" meets "New South".

Greenville is the primary city of "the Upstate" of South Carolina, an area that includes the six counties of northwestern South Carolina along the borders of North Carolina and Georgia. It is the principal city of the Greenville-Anderson-Mauldin Metropolitan Statistical Area (2018 estimated population: 906,626) which is included in the greater Greenville-Spartanburg-Anderson Combined Statistical Area (population 1,478,658 according to 2018 estimates by the U.S. Census Bureau). Greenville County is both the most populous and most dense in the state at 407,383, but because its city limits enclose less than 30 square miles, the population of the city is 67,453 (2015 estimate). Perhaps a more accurate representation of Greenville's size is the urbanized area, which includes all of the city plus adjacent unincorporated areas and some suburbs that have a high population density — this figure is 302,194 (2015 estimate). Visit Greenville website

1 Falls Park on the Reedy. South Main Street. This is a unique and beautiful urban park. The park surrounds the 60-foot Reedy Falls. It creates an oasis in the midst of the bustling city. This is also the original birthplace of what would eventually become known as "Pleasantburg" - later renamed, "Greenville." (updated Aug 2017) 2 Heritage Green. An urban arts and cultural campus with several institutions: The Children's Museum of the Upstate. (updated Jul 2023) 3 Greenville County Museum of Art, 420 College Street, ☏ +1 864-271-7570. W-Sa 10AM–5PM; Su 1PM-5PM. If you weren't expecting great art in this corner of South Carolina, you will be in for a surprise. Regular traveling exhibits combine with the museum's own 32 paintings by Andrew Wyeth to make this a worthwhile stop for any art lover. Free. (updated Aug 2017) Greenville Little Theatre. (updated Aug 2017) Hughes Main Library. (updated Aug 2017) 4 Sigal Music Museum, 516 Buncombe Street, ☏ +1 864-520-8807. Tuesday–Saturday 10AM–5PM, Sunday 1–5PM. Contains among many other things a 1761 harpsichord played by Mozart and an 1845 piano played by Chopin. $7 adult, $6 senior/military/college, $4 student ages 6–18, free for children five and under. (updated Jul 2023) 5 Upcountry History Museum. (updated Aug 2017) 6 Bob Jones University Museum and Gallery, 1700 Wade Hampton Blvd, ☏ +1 864-770-1331. Tu-Su 2-5PM. A thorough presentation of European Old Masters from the fourteenth through the nineteenth centuries including one of the finest collections of Italian Baroque painting in the United States.

As the largest city in the Upstate, Greenville offers many activities and attractions. Greenville's theaters and event venues regularly host major concerts and touring theater companies. Four independent theaters present several plays a year. 1 TD Convention Center. This is the largest convention center between Atlanta, Georgia and Washington, DC, has more than 315,000 square feet of exhibition space and 88,000 square feet of meeting and conference space. Many trade shows, conventions, and other events are held here each year. 2 Bon Secours Wellness Arena. Formerly the Bi-Lo Center, it is a 16,000-seat arena in downtown Greenville which hosts major concerts and sporting events each year. Greenville Swamp Rabbits, 650 N Academy St. Greenville's ECHL hockey team since 2010. Minor league affiliate to the Carolina Hurricanes. 3 Centre Stage, Greenville's Professional Theater. Stage is a year-round, 285-seat professional theater offering a wide range of entertainment that includes music, comedy, drama and special events within easy walking distance of Falls Park and the historic West End. Free parking, assistive listening devices, art exhibitions, chamber music concerts, independent film screenings, galas and more await visitors to this state-of-the-art performance facility, noted for its unique configuration, comfort and intimacy. 4 Peace Center. A performing arts center that hosts touring Broadway shows, symphonies, concerts, and civic events.

With over 80 restaurants in Downtown, Greenville has become known as a culinary center in South Carolina. Below are the most popular in distinct Greenville areas. 1 The Cazbah, 16 West McBee Avenue, ☏ +1 864-241-9909, fax: +1 864-241-9910. Tapas restaurant and wine bar. Outdoor seating available. 2 Grill Marks, 209 S. Main Street, ☏ +1 864-233-5825. 3 Nose Dive, 116 South Main Street, ☏ +1 864-373-7300. A casual gastropub offering high quality pub fare, unique cocktails, a distinctive wine list and handcrafted brews that provides a neighborhood social scene on Main Street. 4 Ristorante Bergamo, 100 North Main Street, ☏ +1 864-271-8667. Tu-Sa 5:30-9:30PM. Modern Northern Italian cuisine. Try the in-house made limoncello. Reservations highly recommended. 5 Roost, 220 North Main Street (at the Hyatt), ☏ +1 864-298-2424. Lunch 11AM-3PM. Dinner 5-10PM. Bar 3-11PM. Focused on local, organic, and seasonal food. 6 Soby's New South Cuisine, 207 South Main Street, ☏ +1 864-232-7007. Tu-Sa 5:30-9:30PM. Soby’s is a blend of contemporary cuisine infused with traditional southern ingredients. Signature dishes include Barbecue Shrimp and Grits, Fried Green Tomatoes with Jalapeno Pimento Cheese, and Crab Cakes Remoulade. The wine list offers more than 500 selections and is a Wine Spectator Magazine award-winner for the past eight years, a 'Best of Award of Excellence' the past two. 7 Sushi Murasaki, 4 South Main Street, ☏ +1 864-271-2452. Delicious, fresh assortment of sushi in a modern restaurant. Licensed to serve beer, wine and liquor.

1 Carolina Ale House, 113 South Main Street, ☏ +1 864-351-0521. 11AM-2PM. Sports bar. Rooftop seating available, open air weather permitting. 2 Connolly's Irish Pub, 24 East Court Street, ☏ +1 864-467-0300. M-Sa 4:30PM-2AM. 3 Northampton Wines & The Wine Café, 211-A East Broad Street, ☏ +1 864-271-3919. M-Sa 9AM-9PM; Wine Café serving dinner M-Sa from 5PM. Retail store and wine bar. 4 Coffee Underground, 1 East Coffee Street (Underneath Ristorante Bergamo), ☏ +1 864-298-0494, [email protected]. M-Th 7AM-11PM; F 7AM-midnight; Sa 8AM-midnight; Su 8AM-10PM. Locally-owned coffee house and bistro with a cozy & friendly atmosphere. Take in performances in the Theater, where weekly performances by comedians, poets & singer-songwriters are hosted. Coffee roasted in-house. Also serving beer, wine, and cocktails. 5 Methodical Coffee, 101 North Main Street, ☏ +1 864-735-8407. Su-Th 7AM-6PM; F Sa 8AM-10PM. Cool, hip and cozy coffee spot serving college kids & locals. (updated Aug 2017) 6 O-CHA Tea & Coffee Bar, 300 River St #122, ☏ +1 864-715-9977. Cozy corner cafe spot serving bubble & loose-leaf teas, pastries, sandwiches and coffee too. (updated Aug 2017)

1 Comfort Inn Greenville - Haywood Mall (former Hampton Inn), 246 Congaree Rd (from I-85 exit 54 onto I-385 north to exit 39, left at end of exit and right at 2nd light), ☏ +1 864-288-1200. Check-in: 3PM, check-out: 11AM. 5 minutes from I-85 and 5 minutes from downtown Greenville across from the only major shopping mall in Greenville. 2 Econo Lodge Inn & Suites (former Microtel), 20 Interstate Court, ☏ +1 864-297-7866. Check-in: 3PM, check-out: 11AM. 3 Hampton Inn Greenville/Travelers Rest, 593 Roe Center Court, ☏ +1 864-834-5550, fax: +1 864 660-0015. Check-in: 3PM, check-out: 11AM. A standard-issue Hampton Inn which is the closest hotel to Furman University. $80-100. 4 Hyatt Place Greenville/Haywood, 40 West Orchard Park Drive, ☏ +1 864-232-3000. 8 miles from the Greenville-Spartanburg International Airport and three miles from downtown Greenville. (updated Feb 2018) 5 Hyatt Regency Greenville, 220 North Main Street. 330 total rooms, 17 luxurious suites, and 25,000 square feet of flexible meeting space featuring Greenville's largest hotel ballroom. A contemporary downtown hotel. 6 Marriott Courtyard Greenville Downtown, 50 W Broad Street, ☏ +1 864-451-5700. Check-in: 3PM, check-out: noon. In downtown Greenville. 7 Marriott Courtyard Greenville Haywood Mall, 70 Orchard Park Drive, ☏ +1 864-234-0300. In the Haywood Mall shopping and dining district. 8 Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd, 1024 Woodruff Road, ☏ +1 864-297-3811. Check-in: 3PM, check-out: 11AM.

Greenville is served by two airports. Greenville-Spartanburg International Airport (GSP), in nearby Greer, is the state's second busiest airport. Greenville Downtown Airport (GMU) is used for private and some cargo air service. Amtrak serves Greenville via its Crescent line, running daily from New Orleans to New York City's Penn Station, with stops including Atlanta, Charlotte, and Washington, D.C. Northbound trains are in Greenville at 5AM and southbound trains at 11PM. 1 Greenville station 1120 W Washington St. Greenville is on the Interstate 85 corridor, linking it to Atlanta and Charlotte, and Interstate 26, which is in nearby Spartanburg, goes northwest through Asheville on to Tennessee, and southeast on to Charleston. It is also at the northern terminus of the Interstate 385 corridor. The other freeways that converge in the area include Interstate 185 and U.S. Highway 123 (Calhoun Memorial Highway). Other major highways include U.S. Highway 25, Business U.S. Highway 25, U.S. Highway 29 and U.S. Highway 276. Main Street is home to many of the downtown area's shopping and dining destinations. Greyhound offers service to Greenville on its route between Charlotte and Atlanta. The station is at 9 Hendrix Dr.

Greenlink, Main Office: 1021 S. Main St; Transfer Center: 100 W. McBee Avenue, +1 864-467-5001. Greenlink offers 11 fixed routes to destinations all across Greenville County. All Greenlink buses are wheelchair-accessible, and each Greenlink bus is equipped with a bike rack to make commuting easier for bike riders. Free WiFi is available on all Greenlink Buses. Single rides $1.50; day passes $5.00; 20-ride pass $27.00; discounted fares available for children and seniors. Yellow Cab of Greenville, 529 W Washington St, +1 864-233-6666, Downtown Pedicab has eight pedicabs in downtown Greenville. Downtown Trolley. The City of Greenville operates two downtown trolleys.

Travel tips adapted from Greenville (South Carolina) on Wikivoyage, licensed CC BY-SA 4.0. Content summarized; visit the source for the full article. See our methodology for how we use it.

How Much Time Do You Have?

Pick your one-way drive time and see where you can go from Greenville, SC.

No routes in this time range.

destinations from Greenville, SC.

Trips to Greenville, SC

Nearby Hubs

Other cities within driving distance of Greenville, SC that also have route pages.

Escape Planner

Where to go from Greenville, SC?

Curated day trips, weekend getaways, and overnight routes — grouped by how much time you have and the kind of trip you want.

Drives from Greenville, SC in your inbox

Monthly note with new routes, weekend drive ideas, and seasonal picks for SC. No spam, unsubscribe anytime.

Browse more SC road trips or choose a route from Greenville, SC above.