Frankie's of Columbia
Around the midpoint, right off the route
Columbia, South Carolina
Hours: 12–10 pm
+18037812342
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
4h 8m
Distance
219.3 mi
353 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$34
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Greenville, SC to Sullivans Island, SC is 219.3 miles and takes about 4h 8m via I 26, with a fuel budget near $34 and enough daylight to finish in a day. This trip stays within South Carolina, beginning in the Southeast region and ending on the coast. With 97% highway driving, expect a straightforward trip that's primarily about covering ground efficiently. You'll likely find this route to be a practical choice for a quick getaway or a convenient way to reach the Charleston area without significant detours.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
109.7 miles from Greenville, SC
A natural place for your longest stop of the day , about 2h 2m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 26 | 158.6 mi | 2h 54m |
| Golden Strip Freeway | 31.6 mi | 34m |
| Mark Clark Expressway | 11.9 mi | 14m |
| I 385 | 10.5 mi | 12m |
| Ben Sawyer Boulevard | 2.2 mi | 3m |
| Chuck Dawley Boulevard | 0.8 mi | 1m |
| Rivers Avenue | 0.8 mi | 1m |
| East North Street | 0.5 mi | <1m |
Step-by-step road directions between Greenville, SC and Sullivans Island, SC.
Start on US 29
Turn left onto East North Street
Continue on I 385
Keep slight left at fork onto I 385
Merge onto I 26
Keep slight right at fork onto I 26
Take the exit
Keep slight left at fork
Keep slight right at fork
Turn left onto Remount Road
Turn right onto US 52; US 78
Take the ramp
Merge onto I 526
Continue on I 526 Bus
Turn left onto Myrick Road
At end of road, turn right onto Rifle Range Road
Turn left onto SC 703
Continue on SC 703
Turn right
Turn right
Arrive at destination
For this 4-hour drive, leaving Greenville, SC in the morning is ideal to maximize daylight and avoid potential afternoon traffic. Since it's a single-day trip, you can be flexible with your timing. There's only one recommended stop, so you can decide on the fly if you need a break. Keep an eye on your fuel gauge, especially during the 158.6-mile stretch on I 26, as services can be spaced out. The estimated fuel cost is around $34, so factor that into your budget.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 48 miles or 54m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 109.7 miles or 2h 2m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 19m
Traffic, exits, and arrival timing usually matter more near Sullivans Island, SC than in the middle of the route.
Open the route before leaving Greenville, SC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Greenville, SC
This is one driving day of about 219.3 miles and 4h 8m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
110 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 48 miles helps settle the day before fatigue starts building.
The midpoint is around 109.7 miles from Greenville, SC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 26 if your tank is already low. That segment runs about 158.6 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Columbia, South Carolina
Around the midpoint, right off the route
Hours: 12–10 pm
+18037812342
Prophet Coffee
North Charleston, South Carolina
Top Coffee Stop
Greenville, South Carolina
Near the start, right off the route
Hours: 7 am–2 pm
+18643739150
The Village Grind
Greenville, South Carolina
Inspire Coffee House
Greenville, South Carolina
Around the midpoint, right off the route
Columbia, South Carolina
Hours: 12–10 pm
+18037812342
Visit websiteNear the end, short detour
North Charleston, South Carolina
Hours: 7 am–2 pm
Visit websiteNear the end, ~10 min detour
Mt Pleasant, South Carolina
Hours: 7 am–5 pm
Visit websiteNear the end, ~12 min detour
Mt Pleasant, South Carolina
Hours: 7 am–2 pm
+18432848283
Visit websiteNear the start, right off the route
Greenville, South Carolina
Hours: 7 am–2 pm
+18643739150
Visit websiteNear the start, short detour
Greenville, South Carolina
Hours: 8 am–4 pm
Near the start, short detour
Greenville, South Carolina
Hours: 7:30 am–3:30 pm
+18643265147
Visit websiteNear the end, short detour
Mt Pleasant, South Carolina
Hours: 7 am–5 pm
Visit websiteAround the midpoint, short detour
Little Mountain, South Carolina
Hours: 6 am–6 pm
+18038164196
Visit websiteNear the end, short detour
Isle of Palms, South Carolina
Hours: 7 am–1 pm
+18438856303
Visit websiteNear the end, short detour
North Charleston, South Carolina
Hours: 7:30 am–3 pm
Near the start, right off the route
Greenville, South Carolina
Hours: Open 24 hours
Visit websiteAround the midpoint, short detour
Columbia, South Carolina
Hours: 7 am–7 pm
Visit websiteLater in the drive, short detour
Harleyville, South Carolina
Hours: 9 am–5 pm
+18434879988
Visit websiteNear the end, short detour
Mt Pleasant, South Carolina
Hours: 5 am–12 pm
+18438844440
Visit websiteNear the end, ~11 min detour
Mt Pleasant, South Carolina
Hours: 9 am–5 pm
+18548889893
Visit websiteAround the midpoint, ~12 min detour
Lexington, South Carolina
Hours: 11 am–8 pm
+18032179221
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 11.1 and 201.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Keep slight left at fork onto I 385 / Golden Strip Freeway
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight right at fork onto I 26 toward Charleston
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward Aviation Avenue, Remount Road
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward Remount Road, Hanahan
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight right at fork toward Remount Road, Hanahan
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Regular Gas
$34.29 one way
$68.59 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.34 | $37.50 | $74.99 |
| premium | $4.70 | $40.59 | $81.18 |
| diesel | $5.61 | $48.42 | $96.84 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$34
Meals
$25–$50
Total
$59–$84
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 76.7 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 65.8 | 0 | $23.03 | $10.53 |
| Efficient EV | 54.8 | 0 | $19.19 | $8.77 |
| EV Truck/SUV | 87.7 | 1 | $30.70 | $14.04 |
Gas CO2
77 kg
EV CO2
26 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in Greenville on Sunday
Local time
6:32 AM
EDT
Current temp
49°F
Unavailable
Destination
Morning in Sullivans Island on Sunday
Local time
6:32 AM
EDT
Current temp
74°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Historical Park
Two forts stand at the entrance of Charleston Harbor. Patriots inside a palmetto log fort, later named Fort Moultrie, defeated the Royal Navy in 1776. As Charleston blazed a path towards secession to...
National Park
Astonishing biodiversity exists in Congaree National Park, the largest intact expanse of old growth bottomland hardwood forest remaining in the southeastern United States. Waters from the Congaree and...
Park data from the National Park Service API. Alerts update every 2 hours.
This drive is almost entirely on highways, with 97% of the 219.3 miles spent on major interstates and freeways. You'll encounter the longest continuous stretch on I 26, covering 158.6 miles. Expect a mostly highway profile until the final portion of your trip, where you'll transition to surface roads for the last few miles into Sullivans Island. Be prepared for frequent exits and merges as you navigate these high-speed corridors.
This is a straightforward highway drive that stays mostly on I 26 and Golden Strip Freeway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 11.1 miles in near I 385 / Golden Strip Freeway.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 17 significant decision points across 219.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 11.1 miles (I 385 / Golden Strip Freeway): Highway fork - watch signs carefully. Lane positioning matters here; at 98.4 miles (I 26): Highway fork - watch signs carefully. Lane positioning matters here; at 201.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Greenville, SC and Sullivans Island, SC, road signs point toward Charleston and Hanahan.
Charleston
Hanahan
Greenville has been described as Athens, Georgia for adults. It is the county seat and largest city of Greenville County, South Carolina, United States. Greenville is also the center of the largest metropolitan area of South Carolina. Columbia, Charleston, and North Charleston have more people, but the urban area around Greenville is larger. With its historic homes and modern office towers, Greenville is said to be where "Old South" meets "New South".
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 4h 8m. Total distance: 219.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 8m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (97%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Greenville, SC or browse trips ending in Sullivans Island, SC.
Looking for more statewide routes? Browse SC road trips.