Biloxi to Water Valley is 302 miles and takes about 5 hours 57 minutes via US 49 and I-55, with a fuel budget near $48 and enough daylight to finish in a day. This trip stays within Mississippi, beginning in the Southeast region and ending in the same area. Given its highway focus, this is a straightforward drive that can be completed in a single day. You'll spend most of your time on major roads, making it a practical option for getting from the Gulf Coast inland without much fuss.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
151.2 miles from Biloxi, MS
A natural place for your longest stop of the day
, about 3h 7m into the drive
.
Main Roads
Road
Distance
Duration
US 49
135 mi
2h 46m
I 55
116.5 mi
2h 6m
MS 7
23.4 mi
26m
MS 15
20.7 mi
24m
I 110
3.1 mi
4m
South Main Street
1.4 mi
2m
Frostland Drive
0.6 mi
1m
Division Street
0.5 mi
1m
Longest stretch:
US 49
— 135 mi, about 2h 46m
Traffic on I-55
Hour-of-day weekday pattern from 49 FHWA count stations on your route.
Peak
4 PM
~2,842 veh/hr typical
Quietest
2 AM
~151 veh/hr
Peak-to-quiet ratio
18.8×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Biloxi, MS and Water Valley, MS.
1
Start on Howard Avenue
91 ft·6 sec·Howard Avenue
2
Turn right onto Main Street
0.5 mi·1 min·Main Street
3
Turn left onto Division Street
0.5 mi·1 min·Division Street
4
Take the ramp onto Bohn Street
139 ft·3 sec·Bohn Street
5
Turn straight
0.3 mi·37 sec
6
Merge onto I 110
3.1 mi·4 min·I 110
7
Continue on MS 15; MS 67
21 mi·24 min·MS 15; MS 67
Use the straight lane.
8
Keep slight right at fork
0.4 mi·47 sec
Toward US 49 North: Hattiesburg, Jackson
9
Merge onto US 49
40 mi·46 min·US 49
Use the straight lane.
10
Continue on US 49
2.4 mi·2 min·US 49
Use the straight / slight right lanes.
11
Turn straight onto US 49
10 mi·16 min·US 49
Use the straight lane.
12
Continue on US 49; MS 42
5.4 mi·6 min·US 49; MS 42
Use the straight lane.
13
Continue on US 49
5.3 mi·6 min·US 49
Use the straight lane.
14
Continue on US 49
0.2 mi·14 sec·US 49
Use the straight lane.
15
Continue on US 49
4.2 mi·4 min·US 49
Use the straight lane.
16
Continue on US 49
66 mi·1 hr 20 min·US 49
Use the straight lane.
17
Take the exit onto US 49
0.2 mi·21 sec·US 49
18
Keep slight left at fork onto US 49
0.7 mi·1 min·US 49
Toward Jackson
19
Keep slight right at fork onto US 49
0.9 mi·1 min·US 49
20
Merge onto I 55
117 mi·2 hr 6 min·I 55
21
Take the exit onto MS 7
23 mi·26 min·MS 7
Toward MS 7 North: Coffeeville
22
Turn right onto MS 32, MS 315
0.6 mi·1 min·Frostland Drive
23
At end of road, turn left onto MS 315
1.4 mi·2 min·South Main Street
24
Arrive at destination
Main Street
Trip Plan
To make the most of this 5 hour 57 minute drive, consider leaving early in the morning to maximize daylight. With a total distance of 302 miles, it's definitely a one-day trip, so you won't need to plan for an overnight stop. Keep an eye on your fuel as you approach the 135-mile mark on US 49, as services might be less frequent in that stretch. The $48 fuel cost is an estimate, so it's always wise to have a little extra buffer.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 151.2 miles from Biloxi, MS, or about 3h 7m into the drive.
The longest continuous stretch on this route runs about 135 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 67 miles or 1h 21m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 151.2 miles or 3h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 55m
Traffic, exits, and arrival timing usually matter more near Water Valley, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Biloxi, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Biloxi, MS
This is one driving day of about 302.4 miles and 5h 57m.
Your first comfortable stop window is around 67 miles from Biloxi, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 49 for about 135 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 13
5 decision points cluster between mile 1 and 301 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
1 mi into trip|~3m in|Bohn Street
Take the ramp onto Bohn Street
Navigation decision point
6
25.1 mi into trip|~32m in
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 49 North: Hattiesburg, Jackson
5
25.5 mi into trip|~33m in|US 49
Merge onto US 49
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
5
158.9 mi into trip|~3h 17m in|US 49
Keep slight left at fork onto US 49 toward Jackson
Highway fork - watch signs carefully
Toward Jackson
5
301 mi into trip|~5h 54m in|MS 315 / South Main Street
At end of road, turn left onto MS 315 / South Main Street
Navigation decision point
Fuel & Cost
Regular Gas
$46.48 one way
$92.96 round trip
$3.90/gal25.4 MPG avg106 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.32
$51.41
$102.82
premium
$4.65
$55.32
$110.65
diesel
$5.35
$63.69
$127.39
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$46
Meals
$25–$50
Total
$71–$96
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 105.8 kg one way.
Prices: EIA weekly data, 2026-06-01.
Driving Electric?
About $32 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
90.7
1
$31.75
$14.52
Efficient EV
75.6
0
$26.46
$12.10
EV Truck/SUV
121
1
$42.34
$19.35
Gas CO2
106 kg
EV CO2
35 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jun 1, 2026
Origin
Biloxi, MS
Afternoon
in Biloxi on Wednesday
Local time
2:05 PM
CDT
Current temp
79°F
Partly Cloudy
W 5 mph5% chanceLive forecast
Flood Warning
Flood Warning issued May 31 at 7:37PM CDT until June 3 at 7:00AM CDT by NWS New Orleans LA
Flood Warning
Flood Warning issued May 31 at 7:35PM CDT until June 1 at 10:00AM CDT by NWS New Orleans LA
Destination
Water Valley, MS
Afternoon
in Water Valley on Wednesday
Local time
2:05 PM
CDT
Current temp
71°F
Mostly Clear
0 mph8% chanceLive forecast
Flood Warning
Flood Warning issued May 31 at 7:37PM CDT until June 3 at 7:00AM CDT by NWS New Orleans LA
Flood Warning
Flood Warning issued May 31 at 7:35PM CDT until June 1 at 10:00AM CDT by NWS New Orleans LA
72°F
New Haven, MS
151 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 57m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
4 mi from route
~10 min detour
Free
near mile 166.8
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This drive is almost entirely on highways, with a 99% highway share. You'll encounter a longest stretch of 135 miles on US 49 before transitioning to I-55 and then MS 7. Expect to see frequent exits for much of the drive, especially on the interstate portions.
99% highway — fuel and pacing are the main things to plan.
24 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 135 mi on US 49.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on US 49 and I 55. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 1 miles in near Bohn Street.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 13 significant decision points across 302.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 1 miles (Bohn Street): Navigation decision point; at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.5 miles (US 49): Merge point - match speed before joining. Lane positioning matters here.
Elevation Profile
Mostly flat terrain
405 ft20 ft
Total Climb
678 ft
Total Descent
410 ft
Highest Point
405 ft
~259.2 mi in
Elevation Range
385 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Biloxi, MS to Water Valley, MS, road signs begin pointing toward Jackson along the way.
Jackson
25.1 mi in|~32m
Detours Along the Way
Tagged by where each one fits in your drive — first break, midpoint, final stretch.
Biloxi is a city in Harrison County, on the Gulf Coast of Mississippi. It's well known for its beaches and nine casinos. It is also home to the "Jefferson Davis Presidential Library and Museum", which serves as a museum of the Confederacy.
Top landmarks
•Jefferson Davis Presidential Library and Museum — presidential library and museum for Confederate States President Jefferson Davis...
•Beauvoir — post-war home of the former President of the Confederate States of America, Jeff...
•Biloxi Light — lighthouse in Mississippi, United States
Doable as a same-day drive at 5h 57m. Total distance: 302.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 57m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (99%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 135 miles on US 49. The full list of main roads is in the Roads section above.
Yes — we found about 1 rest area or service plaza within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Water Valley, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 1 rest area along the route for bathroom stops.
The main spots that need attention: at 1 miles (Bohn Street): Navigation decision point; at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.5 miles (US 49): Merge point - match speed before joining. Lane positioning matters here.
Yes — Medgar and Myrlie Evers Home National Monument. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 6.0 hours each way, a round trip means 11.9 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Water Valley, MS before the return drive.
