Trip from Biloxi, MS to Hernando, MS
Pin this tripCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Jun 3, 2026 · Editorial standards
Drive Time
6h 41m
Distance
345.9 mi
557 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$53
one way
EV Charging
Unknown
Best Time to Leave
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Biloxi, MS
Wikimedia Commons
Hernando, MS
Wikimedia Commons
Trip Overview
Biloxi to Hernando is 345.9 miles and takes about 6h 41m via I 55 and US 49, with a fuel budget near $54 and enough daylight to finish in a day. This trip stays within Mississippi, moving from the Southeast region's coast up into its inland areas. The route is almost entirely highway, making for a straightforward drive. It's a solid option if you need to cover ground efficiently between these two points in the state.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
172.9 miles from Biloxi, MS
A natural place for your longest stop of the day , about 3h 33m into the drive .
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 55 | 184 mi | 3h 19m |
| US 49 | 135 mi | 2h 46m |
| MS 15 | 20.7 mi | 24m |
| I 110 | 3.1 mi | 4m |
| East Commerce Street | 1.1 mi | 1m |
| Division Street | 0.5 mi | 1m |
| Main Street | 0.5 mi | 1m |
| US 51 | <0.1 mi | <1m |
Traffic on I-55
Hour-of-day weekday pattern from 57 FHWA count stations on your route.
Peak
4 PM
~2,443 veh/hr typical
Quietest
2 AM
~141 veh/hr
Peak-to-quiet ratio
17.3×
busier at peak than in the quiet hours
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Biloxi, MS and Hernando, MS.
Start on Howard Avenue
Turn right onto Main Street
Turn left onto Division Street
Take the ramp onto Bohn Street
Turn straight
Merge onto I 110
Continue on MS 15; MS 67
Keep slight right at fork
Merge onto US 49
Continue on US 49
Turn straight onto US 49
Continue on US 49; MS 42
Continue on US 49
Continue on US 49
Continue on US 49
Continue on US 49
Take the exit onto US 49
Keep slight left at fork onto US 49
Keep slight right at fork onto US 49
Merge onto I 55
Take the exit
Turn left onto MS 304
Turn right onto US 51
Arrive at destination
Trip Plan
With a drive time of under 7 hours, this trip is easily manageable in a single day. Aim to depart in the morning to allow for any unexpected delays and to have plenty of daylight. The route involves one main road, I 55 for a significant portion, so keep an eye on your fuel gauge, especially during the 184-mile stretch. While there are no specific stops mandated by the route, consider planning a break around the halfway point. Given the highway-centric nature, most services will be readily available at exits.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 76 miles or 1h 35m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 172.9 miles or 3h 33m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 35m
Traffic, exits, and arrival timing usually matter more near Hernando, MS than in the middle of the route.
Before You Leave
Open the route before leaving Biloxi, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Biloxi, MS
This is one driving day of about 345.9 miles and 6h 41m.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
173 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
A short stop after about 76 miles helps settle the day before fatigue starts building.
The midpoint is around 172.9 miles from Biloxi, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 55 if your tank is already low. That segment runs about 184 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Stops Along Your Drive
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Love's Travel Stop
Service Plaza
Dizzy Dean Rest Area
Love's Travel Stop
Doughboys
Rest Area
Love's Travel Stop
Flying J Travel Center
Service Plaza
Love's Travel Stop
Pilot Travel Center
Pilot Travel Center
Petro Stopping Centers
Love's Travel Stop
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 145 decision points cluster between mile 1 and 159.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the ramp onto Bohn Street
Navigation decision point
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Merge onto US 49
Merge point - match speed before joining. Lane positioning matters here
Keep slight left at fork onto US 49 toward Jackson
Highway fork - watch signs carefully
Keep slight right at fork onto US 49
Highway fork - watch signs carefully
Fuel & Cost
Regular Gas
$53.17 one way
$106.33 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.32 | $58.80 | $117.61 |
| premium | $4.65 | $63.28 | $126.57 |
| diesel | $5.35 | $72.86 | $145.71 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$53
Meals
$25–$50
Total
$78–$103
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 121 kg one way. Prices: EIA weekly data, 2026-06-01.
Driving Electric?
About $36 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 103.8 | 1 | $36.32 | $16.60 |
| Efficient EV | 86.5 | 0 | $30.27 | $13.84 |
| EV Truck/SUV | 138.4 | 1 | $48.43 | $22.14 |
Gas CO2
121 kg
EV CO2
40 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Origin
Biloxi, MS
Afternoon in Biloxi on Wednesday
Local time
2:11 PM
CDT
Current temp
79°F
Partly Cloudy
Flood Warning
Flood Warning issued May 31 at 7:37PM CDT until June 3 at 7:00AM CDT by NWS New Orleans LA
Flood Warning
Flood Warning issued May 31 at 7:35PM CDT until June 1 at 10:00AM CDT by NWS New Orleans LA
Destination
Hernando, MS
Afternoon in Hernando on Wednesday
Local time
2:11 PM
CDT
Current temp
71°F
Mostly Clear
Flood Warning
Flood Warning issued May 31 at 7:37PM CDT until June 3 at 7:00AM CDT by NWS New Orleans LA
Flood Warning
Flood Warning issued May 31 at 7:35PM CDT until June 1 at 10:00AM CDT by NWS New Orleans LA
72°F
New Haven, MS
173 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 41m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Emmett Till and Mamie Till-Mobley National Monument
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
Park data from the National Park Service API. Alerts update every 2 hours.
What kind of drive is this?
Expect to be on the highway for 99% of this 345.9-mile drive. The longest continuous stretch you'll encounter is 184 miles on I 55. This means you'll experience extended periods of cruising with minimal turns. The route profile is described as mostly highway, so you'll likely notice a consistent flow of traffic and well-spaced exits for most of the 6h 41m trip.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on I 55 and US 49. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 1 miles in near Bohn Street.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 345.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 1 miles (Bohn Street): Navigation decision point; at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.5 miles (US 49): Merge point - match speed before joining. Lane positioning matters here.
Elevation Profile
Mostly flat terrain
Total Climb
838 ft
Total Descent
477 ft
Highest Point
513 ft
~123.5 mi in
Elevation Range
493 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Biloxi, MS to Hernando, MS, road signs begin pointing toward Jackson along the way.
Jackson
About the Cities
Starting in Biloxi, MS
Full guide →Founded 1720
Biloxi is a city in Harrison County, on the Gulf Coast of Mississippi. It's well known for its beaches and nine casinos. It is also home to the "Jefferson Davis Presidential Library and Museum", which serves as a museum of the Confederacy.
Top landmarks
- • Jefferson Davis Presidential Library and Museum — presidential library and museum for Confederate States President Jefferson Davis...
- • Beauvoir — post-war home of the former President of the Confederate States of America, Jeff...
- • Biloxi Light — lighthouse in Mississippi, United States
Arriving in Hernando, MS
Full guide →Founded 1839
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 41m. Total distance: 345.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 41m drive, plan rest stops for pacing.
Frequently Asked Questions
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NPS for national parks, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore More
Explore more options from Biloxi, MS or browse trips ending in Hernando, MS.
Looking for more statewide routes? Browse MS road trips.