Biloxi to Marks is 330.2 miles and takes about 6h 32m via I 55 and US 49, with a fuel budget near $48 and enough daylight to finish in a day. This trip stays within the Southeast region, primarily traversing Mississippi. Given its mostly highway profile, expect a straightforward drive with minimal detours. This route is best suited for a single-day trip if you're looking for an efficient way to cover ground between the two points.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
165.1 miles from Biloxi, MS
A natural place for your longest stop of the day
, about 3h 24m into the drive
.
Main Roads
Road
Distance
Duration
I 55
147.9 mi
2h 40m
US 49
135 mi
2h 46m
US 278
21.1 mi
30m
MS 15
20.7 mi
24m
I 110
3.1 mi
4m
Division Street
0.5 mi
1m
Main Street
0.5 mi
1m
MS 3
0.2 mi
<1m
Longest stretch:
I 55
— 147.9 mi, about 2h 40m
Traffic on I-55
Hour-of-day weekday pattern from 49 FHWA count stations on your route.
Peak
4 PM
~2,842 veh/hr typical
Quietest
2 AM
~151 veh/hr
Peak-to-quiet ratio
18.8×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Biloxi, MS and Marks, MS.
1
Start on Howard Avenue
91 ft·6 sec·Howard Avenue
2
Turn right onto Main Street
0.5 mi·1 min·Main Street
3
Turn left onto Division Street
0.5 mi·1 min·Division Street
4
Take the ramp onto Bohn Street
139 ft·3 sec·Bohn Street
5
Turn straight
0.3 mi·37 sec
6
Merge onto I 110
3.1 mi·4 min·I 110
7
Continue on MS 15; MS 67
21 mi·24 min·MS 15; MS 67
Use the straight lane.
8
Keep slight right at fork
0.4 mi·47 sec
Toward US 49 North: Hattiesburg, Jackson
9
Merge onto US 49
40 mi·46 min·US 49
Use the straight lane.
10
Continue on US 49
2.4 mi·2 min·US 49
Use the straight / slight right lanes.
11
Turn straight onto US 49
10 mi·16 min·US 49
Use the straight lane.
12
Continue on US 49; MS 42
5.4 mi·6 min·US 49; MS 42
Use the straight lane.
13
Continue on US 49
5.3 mi·6 min·US 49
Use the straight lane.
14
Continue on US 49
0.2 mi·14 sec·US 49
Use the straight lane.
15
Continue on US 49
4.2 mi·4 min·US 49
Use the straight lane.
16
Continue on US 49
66 mi·1 hr 20 min·US 49
Use the straight lane.
17
Take the exit onto US 49
0.2 mi·21 sec·US 49
18
Keep slight left at fork onto US 49
0.7 mi·1 min·US 49
Toward Jackson
19
Keep slight right at fork onto US 49
0.9 mi·1 min·US 49
20
Merge onto I 55
148 mi·2 hr 40 min·I 55
21
Take the exit
0.2 mi·30 sec
Toward US 278, MS 6: Batesville, Oxford
22
Keep slight left at fork
271 ft·8 sec
23
Merge onto US 278; MS 6
21 mi·30 min·US 278; MS 6
24
Turn left onto MS 3
0.2 mi·31 sec·MS 3
25
Turn left onto Lamar Street
363 ft·16 sec·Lamar Street
26
Turn right onto 1st Street
402 ft·17 sec·1st Street
27
Arrive at destination
1st Street
Trip Plan
For this 6-hour drive, leaving in the morning will give you plenty of time to reach Marks before evening. With only one recommended stop, you can plan your breaks strategically, perhaps around the halfway point. Keep an eye on your fuel as you approach Marks; while the $48 budget is an estimate, knowing where the last services are on US 278 could be helpful. Since this is a single-day trip, you have flexibility if you encounter any unexpected delays.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 165.1 miles from Biloxi, MS, or about 3h 24m into the drive.
The longest continuous stretch on this route runs about 147.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 73 miles or 1h 30m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 165.1 miles or 3h 24m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 19m
Traffic, exits, and arrival timing usually matter more near Marks, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Biloxi, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Biloxi, MS
This is one driving day of about 330.2 miles and 6h 32m.
Your first comfortable stop window is around 73 miles from Biloxi, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 55 for about 147.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 17
5 decision points cluster between mile 25.1 and 308.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
25.1 mi into trip|~32m in
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 49 North: Hattiesburg, Jackson
5
25.5 mi into trip|~33m in|US 49
Merge onto US 49
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
5
158.9 mi into trip|~3h 17m in|US 49
Keep slight left at fork onto US 49 toward Jackson
Highway fork - watch signs carefully
Toward Jackson
5
308.4 mi into trip|~6h in
Take the exit toward US 278, MS 6: Batesville, Oxford
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 278, MS 6: Batesville, Oxford
5
308.6 mi into trip|~6h in
Keep slight left at fork
Highway fork - watch signs carefully
Fuel & Cost
Regular Gas
$50.75 one way
$101.50 round trip
$3.90/gal25.4 MPG avg116 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.32
$56.13
$112.27
premium
$4.65
$60.41
$120.82
diesel
$5.35
$69.55
$139.10
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$51
Meals
$25–$50
Total
$76–$101
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 115.5 kg one way.
Prices: EIA weekly data, 2026-06-01.
Driving Electric?
About $35 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
99.1
1
$34.67
$15.85
Efficient EV
82.6
0
$28.89
$13.21
EV Truck/SUV
132.1
1
$46.23
$21.13
Gas CO2
116 kg
EV CO2
39 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jun 1, 2026
Origin
Biloxi, MS
Afternoon
in Biloxi on Wednesday
Local time
2:11 PM
CDT
Current temp
79°F
Partly Cloudy
W 5 mph5% chanceLive forecast
Flood Warning
Flood Warning issued May 31 at 7:37PM CDT until June 3 at 7:00AM CDT by NWS New Orleans LA
Flood Warning
Flood Warning issued May 31 at 7:35PM CDT until June 1 at 10:00AM CDT by NWS New Orleans LA
Destination
Marks, MS
Afternoon
in Marks on Wednesday
Local time
2:11 PM
CDT
Current temp
73°F
Partly Cloudy
0 mph5% chanceLive forecast
Flood Warning
Flood Warning issued May 31 at 7:37PM CDT until June 3 at 7:00AM CDT by NWS New Orleans LA
Flood Warning
Flood Warning issued May 31 at 7:35PM CDT until June 1 at 10:00AM CDT by NWS New Orleans LA
72°F
New Haven, MS
165 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
6 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 32m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
6 mi from route
~14 min detour
Free
near mile 159.4
Emmett Till and Mamie Till-Mobley National Monument
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
21 mi from route
~51 min detour
Free
near mile 330.2
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
You'll be on the highway for 99% of this 330.2-mile drive. The longest uninterrupted stretch is 147.9 miles on I 55, meaning you can settle in for a while. Surface roads don't really come into play until the very end of your trip. Expect a consistent flow of exits and traffic as you navigate through Mississippi's main corridors.
99% highway — fuel and pacing are the main things to plan.
27 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 147.9 mi on I 55.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on I 55 and US 49. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 25.1 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 17 significant decision points across 330.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.5 miles (US 49): Merge point - match speed before joining. Lane positioning matters here; at 158.9 miles (US 49): Highway fork - watch signs carefully.
Elevation Profile
Mostly flat terrain
400 ft20 ft
Total Climb
667 ft
Total Descent
526 ft
Highest Point
400 ft
~141.5 mi in
Elevation Range
380 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Biloxi, MS and Marks, MS, road signs point toward Jackson and Oxford.
Biloxi is a city in Harrison County, on the Gulf Coast of Mississippi. It's well known for its beaches and nine casinos. It is also home to the "Jefferson Davis Presidential Library and Museum", which serves as a museum of the Confederacy.
Top landmarks
•Jefferson Davis Presidential Library and Museum — presidential library and museum for Confederate States President Jefferson Davis...
•Beauvoir — post-war home of the former President of the Confederate States of America, Jeff...
•Biloxi Light — lighthouse in Mississippi, United States
Doable as a same-day drive at 6h 32m. Total distance: 330.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 32m drive, plan rest stops for pacing.
Frequently Asked Questions
The longest stretch is about 147.9 miles on I 55. The full list of main roads is in the Roads section above.
Yes — we found about 1 rest area or service plaza within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Marks, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 1 rest area along the route for bathroom stops.
The main spots that need attention: at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 25.5 miles (US 49): Merge point - match speed before joining. Lane positioning matters here; at 158.9 miles (US 49): Highway fork - watch signs carefully.
Yes — Medgar and Myrlie Evers Home National Monument and Emmett Till and Mamie Till-Mobley National Monument. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 6.5 hours each way, a round trip means 13.1 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Marks, MS before the return drive.
