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Trip from Biloxi, MS to Caledonia, MS

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Sep 6, 2026 · Editorial standards

Drive Time

5h 23m

Distance

271 mi

436 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$40

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
5h 10m ★
6 AM
5h 23m
8 AM
5h 50m
10 AM
5h 33m
12 PM
5h 30m
3 PM
5h 34m
5 PM
5h 49m
8 PM
5h 15m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Biloxi, MS, MS

Biloxi, MS

Wikimedia Commons

Downtown Caledonia, MS, MS

Caledonia, MS

Ollie Craig

Trip Overview

The drive from Biloxi, MS to Caledonia, MS covers 271 miles and takes about 5h 23m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.

The route leans on Lance Corporal Roy M Wheat Memorial Highway, US 45, US 49 for much of the mileage, and the overall profile is mixed highway & surface. The longest uninterrupted segment is about 88.4 miles on Lance Corporal Roy M Wheat Memorial Highway. At current regular gas prices, budget about $39.70 one way before food or hotel costs.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

135.5 miles from Biloxi, MS

A natural place for your longest stop of the day , about 2h 37m into the drive .

Main Roads

Road Distance Duration
Lance Corporal Roy M Wheat Memorial Highway 88.4 mi 1h 35m
US 45 82.8 mi 1h 35m
US 49 42.2 mi 49m
MS 15 20.7 mi 24m
I 59 9 mi 10m
Military Road 8 mi 13m
Caledonia Steens Road 5 mi 9m
US 98 3.3 mi 4m
Longest stretch: Lance Corporal Roy M Wheat Memorial Highway — 88.4 mi, about 1h 35m

Traffic on I-59

Hour-of-day weekday pattern from 24 FHWA count stations on your route.

Peak

4 PM

~969 veh/hr typical · worst 1,202

Quietest

1 AM

~89 veh/hr

Peak-to-quiet ratio

10.9×

busier at peak than in the quiet hours

12a 6a noon 6p 11p

Averaged across 103 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).

Turn-by-Turn Driving Directions

Step-by-step road directions between Biloxi, MS and Caledonia, MS.

1

Start on Howard Avenue

91 ft · 6 sec · Howard Avenue
2

Turn right onto Main Street

0.5 mi · 1 min · Main Street
3

Turn left onto Division Street

0.5 mi · 1 min · Division Street
4

Take the ramp onto Bohn Street

139 ft · 3 sec · Bohn Street
5

Turn straight

0.3 mi · 37 sec
6

Merge onto I 110

3.1 mi · 4 min · I 110
7

Continue on MS 15; MS 67

21 mi · 24 min · MS 15; MS 67
Use the straight lane.
8

Keep slight right at fork

0.4 mi · 47 sec
Toward US 49 North: Hattiesburg, Jackson
9

Merge onto US 49

40 mi · 46 min · US 49
Use the straight lane.
10

Continue on US 49

2.4 mi · 2 min · US 49
Use the straight / slight right lanes.
11

Take the exit

0.3 mi · 51 sec
12

Merge onto US 98

2.5 mi · 2 min · US 98
Use the straight / slight right lanes.
13

Take the exit onto US 98

0.8 mi · 1 min · US 98
Toward I 59 North, US 98 West: Columbia, Laurel Use the straight / slight right lanes.
14

Merge onto I 59; US 98

88 mi · 1 hr 35 min · Lance Corporal Roy M Wheat Memorial Highway
Use the straight / slight right lanes.
15

Keep slight right at fork onto I 59

9.0 mi · 10 min · I 59
Toward I 59 North, I 20 East: Meridian, Tuscaloosa Use the straight lane.
16

Take the exit

0.3 mi · 47 sec
Toward US 45 North: Macon Use the slight right lane.
17

Merge onto US 45

65 mi · 1 hr 14 min · US 45
Use the straight lane.
18

Keep slight right at fork onto US 45

3.4 mi · 4 min · US 45
Toward US 45 North: Columbus, Aberdeen
19

Continue on US 45

14 mi · 16 min · US 45
20

Continue on Plymouth Bluff Access Road

312 ft · 5 sec · Plymouth Bluff Access Road
Use the straight / slight right lanes.
21

Take the exit

5.4 mi · 6 min
Toward US 82 East, US 45 North, MS 12 East: Columbus
22

Take the exit

0.1 mi · 18 sec
23

Keep slight left at fork

122 ft · 4 sec
24

Enter roundabout onto Military Road

158 ft · 3 sec · Military Road
25

Continue on Military Road

0.1 mi · 12 sec · Military Road
26

Enter roundabout onto Military Road

96 ft · 2 sec · Military Road
27

Continue on Military Road

4.6 mi · 8 min · Military Road
Use the straight lane.
28

At end of road, turn left onto MS 12

3.2 mi · 5 min · Military Road
29

Turn slight left onto Caledonia Steens Road

5.0 mi · 9 min · Caledonia Steens Road
30

Turn straight onto Wolfe Road

0.7 mi · 2 min · Wolfe Road
31

Turn left onto Main Street

69 ft · 1 sec · Main Street
32

Arrive at destination

Main Street

Trip Plan

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 135.5 miles from Biloxi, MS, or about 2h 37m into the drive.
The longest continuous stretch on this route runs about 88.4 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 60 miles or 1h 13m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 135.5 miles or 2h 37m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 15m

Traffic, exits, and arrival timing usually matter more near Caledonia, MS than in the middle of the route.

Before You Leave

+

Open the route before leaving Biloxi, MS so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Biloxi, MS

This is one driving day of about 271 miles and 5h 23m.

Your first comfortable stop window is around 60 miles from Biloxi, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Lance Corporal Roy M Wheat Memorial Highway for about 88.4 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in Clarke County, Mississippi, United States of America

Mid-route town

Meal stop

Quitman, MS

136 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Hattiesburg, MS

Fuel and coffee

A short stop after about 60 miles helps settle the day before fatigue starts building.

Newton, MS

Meal break

The midpoint is around 135.5 miles from Biloxi, MS, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Lance Corporal Roy M Wheat Memorial Highway if your tank is already low. That segment runs about 88.4 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 22

5 decision points cluster between mile 25.1 and 234 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

6
25.1 mi into trip | ~32m in

Keep slight right at fork toward US 49 North: Hattiesburg, Jackson

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward US 49 North: Hattiesburg, Jackson
7
70.4 mi into trip | ~1h 26m in | US 98

Take the exit onto US 98 toward I 59 North, US 98 West: Columbia, Laurel

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward I 59 North, US 98 West: Columbia, Laurel
8
159.6 mi into trip | ~3h 3m in | I 59

Keep slight right at fork onto I 59 toward I 59 North, I 20 East: Meridian, Tuscaloosa

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight lane. Toward I 59 North, I 20 East: Meridian, Tuscalo...
6
168.6 mi into trip | ~3h 14m in

Take the exit toward US 45 North: Macon

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Toward US 45 North: Macon
6
234 mi into trip | ~4h 29m in | US 45

Keep slight right at fork onto US 45 toward US 45 North: Columbus, Aberdeen

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward US 45 North: Columbus, Aberdeen

Fuel & Cost

Regular Gas

$39.70 one way

$79.40 round trip

$3.72/gal 25.4 MPG avg 95 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.13 $44.07 $88.15
premium $4.49 $47.86 $95.72
diesel $5.60 $59.74 $119.47

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$40

Meals

$25–$50

Total

$65–$90

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 94.8 kg one way. Prices: EIA weekly data, 2026-08-31.

Driving Electric?

About $28 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 81.3 1 $28.46 $13.01
Efficient EV 67.8 0 $23.71 $10.84
EV Truck/SUV 108.4 1 $37.94 $17.34

Gas CO2

95 kg

EV CO2

32 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Sep 4, 2026

Origin

Biloxi, MS

Evening in Biloxi on Saturday

Local time

7:12 PM

CDT

Current temp

76°F

Unavailable

Live forecast

Destination

Caledonia, MS

Evening in Caledonia on Saturday

Local time

7:12 PM

CDT

Current temp

72°F

Unavailable

Live forecast

73°F

Quitman, MS

136 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

4 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 23m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

271 mi in 5h 23m — 59% highway, the rest on surface roads. Biggest road: Lance Corporal Roy M Wheat Memorial Highway.

59% highway, the rest on surface roads — varied driving throughout.
32 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 88.4 mi on Lance Corporal Roy M Wheat Memorial Highway.

How Hard Is This Drive?

10/10

This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 25.1 miles in.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 22 significant decision points across 271 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 70.4 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 159.6 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Elevation Profile

Mostly flat terrain

453 ft 20 ft

Total Climb

611 ft

Total Descent

295 ft

Highest Point

453 ft

~154.9 mi in

Elevation Range

432 ft

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Biloxi, MS and Caledonia, MS, road signs point toward Jackson, Laurel, Tuscaloosa and Aberdeen.

Jackson

25.1 mi in | ~32m

Laurel

70.4 mi in | ~1h 26m | via US 98

Tuscaloosa

159.6 mi in | ~3h 3m | via I 59

Aberdeen

234 mi in | ~4h 29m | via US 45

About the Cities

Starting in Biloxi, MS

Full guide →

Founded 1720

Biloxi is a city in Harrison County, on the Gulf Coast of Mississippi. It's well known for its beaches and nine casinos. It is also home to the "Jefferson Davis Presidential Library and Museum", which serves as a museum of the Confederacy.

Top landmarks

  • Jefferson Davis Presidential Library and Museum — presidential library and museum for Confederate States President Jefferson Davis...
  • Beauvoir — post-war home of the former President of the Confederate States of America, Jeff...
  • Biloxi Light — lighthouse in Mississippi, United States

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 5h 23m. Total distance: 271 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

5h 23m drive, comfortable solo distance.

Frequently Asked Questions

The longest stretch is about 88.4 miles on Lance Corporal Roy M Wheat Memorial Highway. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Caledonia, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 25.1 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 70.4 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 159.6 miles (I 59): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Not recommended in a single day. At 5.4 hours each way, a round trip means 10.8 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Caledonia, MS before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.

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