Origin
Tupelo, MS
Late night in Tupelo on Sunday
Local time
2:56 AM
CDT
Current temp
78°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
41m
Distance
30.4 mi
49 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$5
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Tupelo, MS
Wikimedia Commons
Amory, MS
Wikimedia Commons
Tupelo to Amory is 30.4 miles and takes about 41 minutes via US 45 and US 278, with a fuel budget near $5 and enough daylight to finish in a day. This short trip stays within Mississippi, making it an easy excursion. The drive is primarily highway-focused, offering a straightforward connection between these two communities in the Southeast region. Given its brevity, this route is ideal for a quick day trip or as a segment of a larger journey through Mississippi, requiring minimal planning and allowing for flexibility.
| Road | Distance | Duration |
|---|---|---|
| US 45 | 10.8 mi | 13m |
| US 278 | 8.7 mi | 13m |
| Martin Luther King Drive | 7.1 mi | 8m |
| Martin Luther King, Junior Drive | 2.3 mi | 2m |
| East Main Street | 0.5 mi | 1m |
| South Main Street | 0.4 mi | <1m |
| Court Street | <0.1 mi | <1m |
| North Front Street | <0.1 mi | <1m |
Step-by-step road directions between Tupelo, MS and Amory, MS.
Start on North Spring Street
Turn right onto Court Street
Turn right onto North Front Street
Turn left onto East Main Street
Take the ramp
Merge onto US 45; MS 6
Continue on US 45; MS 6
Continue on US 45; US 278
Take the exit onto US 45; US 278
Take the exit onto US 278
Turn left onto US 278
Turn left onto MS 25
Turn right onto 2nd Avenue South
Arrive at destination
5 decision points cluster between mile 0 and 30 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn right onto Court Street
Navigation decision point
Turn left onto East Main Street
Lane positioning matters here
Take the exit onto US 45; US 278 toward US 45 South, US 278 East: Nettleton
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Take the exit onto US 278 toward US 278 East, MS 41 North: Amory, Okalona
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Turn left onto MS 25 / South Main Street
Lane positioning matters here
Regular Gas
$4.59 one way
$9.18 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.21 | $5.04 | $10.08 |
| premium | $4.56 | $5.46 | $10.91 |
| diesel | $5.61 | $6.71 | $13.42 |
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$5
Estimated CO2 emission: 10.6 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $3 in charging · 0 stops · 64% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 9.1 | 0 | $3.19 | $1.46 |
| Efficient EV | 7.6 | 0 | $2.66 | $1.22 |
| EV Truck/SUV | 12.2 | 0 | $4.26 | $1.95 |
Gas CO2
11 kg
EV CO2
4 kg (64% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Tupelo on Sunday
Local time
2:56 AM
CDT
Current temp
78°F
Unavailable
Destination
Late night in Amory on Sunday
Local time
2:56 AM
CDT
Current temp
53°F
Unavailable
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
This route is largely highway-focused, with 64% of the drive utilizing main roads like US 45 and US 278. You'll experience stretches of consistent speed, including a 10.8-mile segment on US 45 where you can maintain momentum. While the profile suggests a highway feel, keep an eye out for transitions as you approach your destination, as local roads like Martin Luther King Drive will eventually guide you into Amory. The drive is designed for efficiency, connecting points A and B with minimal fuss.
This is a straightforward highway drive that stays mostly on US 45 and US 278. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near Court Street.
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 41m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (Court Street): Navigation decision point; at 0.1 miles (East Main Street): Lane positioning matters here; at 10.5 miles (US 45; US 278): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Tupelo, MS to Amory, MS, road signs begin pointing toward Okalona along the way.
Okalona
Weekend Trip
Doable as a same-day drive at 41m. Total distance: 30.4 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
41m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (64%). Straightforward navigation.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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