This 181.1-mile drive from Brandon, Mississippi to Amory, Mississippi is a manageable one-day trip, taking about 3 hours and 41 minutes. Primarily utilizing MS 25 and US 45, this route is almost entirely highway, making for a straightforward journey through the Southeast region of Mississippi. With an estimated fuel cost of $27, it's an economical option for a quick getaway or a connecting drive. You'll find it to be a focused highway experience, perfect for those looking to cover ground efficiently without extensive detours. Consider this route for a no-fuss travel day.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
90.6 miles from Brandon, MS
A natural place for your longest stop of the day
, about 1h 48m into the drive
.
Main Roads
Road
Distance
Duration
MS 25
90 mi
1h 42m
MS 471
46.8 mi
53m
US 45
23.3 mi
29m
MS 8
6.5 mi
9m
Highway 471
6.2 mi
10m
Highway 125
5.2 mi
9m
Hwy 471
1.5 mi
2m
East Government Street
0.5 mi
<1m
Longest stretch:
MS 25
— 90 mi, about 1h 42m
Turn-by-Turn Driving Directions
Step-by-step road directions between Brandon, MS and Amory, MS.
1
Start on US 80
0.5 mi·46 sec·East Government Street
2
Turn right onto MS 471
1.5 mi·2 min·Hwy 471
Use the right lane.
3
Continue on MS 471
6.2 mi·10 min·Highway 471
4
Take the ramp onto MS 471
47 mi·53 min·MS 471
5
Continue on MS 25
33 mi·37 min·MS 25
6
Take the exit onto MS 25
25 mi·29 min·MS 25
7
Keep slight right at fork onto MS 25
2.4 mi·2 min·MS 25
Use the left lane.
8
Continue on MS 25
3.8 mi·4 min·MS 25
9
Keep slight right at fork onto MS 25
26 mi·28 min·MS 25
Toward US 82 East, MS 25 North: Columbus, West Point
10
Take the exit onto US 45
0.5 mi·55 sec·US 45
Toward US 45 North: AberdeenUse the slight right lane.
11
Continue on US 45; MS 50
13 mi·16 min·US 45; MS 50
Use the left lane.
12
Continue on US 45
2.0 mi·2 min·US 45
13
Continue on US 45
1.9 mi·2 min·US 45
14
Continue on US 45
1.8 mi·2 min·US 45
15
Continue on US 45
0.8 mi·55 sec·US 45
16
Continue on US 45
2.2 mi·2 min·US 45
17
Continue on US 45
0.8 mi·52 sec·US 45
18
Continue on US 45
0.3 mi·17 sec·US 45
19
Take the exit
0.3 mi·50 sec
Toward MS 25 North, MS 8 East: Amory
20
Continue on MS 8; MS 25
6.5 mi·9 min·MS 8; MS 25
21
Turn left onto Highway 125
5.2 mi·9 min·Highway 125
22
Turn right onto US 278
0.4 mi·59 sec·US 278
23
Turn left onto MS 25
0.4 mi·40 sec·South Main Street
Use the left lane.
24
Turn right onto 2nd Avenue South
47 ft·2 sec·2nd Avenue South
25
Arrive at destination
2nd Avenue South
Trip Plan
Given the 3-hour and 41-minute duration, this trip is comfortably completed in a single day. Aiming for an early morning departure from Brandon, MS, will allow you to reach Amory, MS, with plenty of daylight remaining. With only one designated stop in the route data, you'll have flexibility in deciding when and where to take breaks, though it's wise to plan for at least one fuel stop, especially considering the longest stretch without a break is 90 miles. Keep an eye on your fuel gauge as you transition onto US 45, as this is a significant portion of your journey.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 90.6 miles from Brandon, MS, or about 1h 48m into the drive.
The longest continuous stretch on this route runs about 90 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 40 miles or 50m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 90.6 miles or 1h 48m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 55m
Traffic, exits, and arrival timing usually matter more near Amory, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Brandon, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Brandon, MS
This is one driving day of about 181.1 miles and 3h 41m.
Your first comfortable stop window is around 40 miles from Brandon, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS 25 for about 90 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 9
5 decision points cluster between mile 0.5 and 180.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.5 mi into trip|~0m in|MS 471 / Hwy 471
Turn right onto MS 471 / Hwy 471
Lane positioning matters here
Use the right lane.
6
112.7 mi into trip|~2h 14m in|MS 25
Keep slight right at fork onto MS 25
Highway fork - watch signs carefully. Lane positioning matters here
Use the left lane.
6
118.9 mi into trip|~2h 21m in|MS 25
Keep slight right at fork onto MS 25 toward US 82 East, MS 25 North: Columbus, West Point
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 82 East, MS 25 North: Columbus, West...
6
145 mi into trip|~2h 50m in|US 45
Take the exit onto US 45 toward US 45 North: Aberdeen
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Toward US 45 North: Aberdeen
6
180.8 mi into trip|~3h 40m in|MS 25 / South Main Street
Turn left onto MS 25 / South Main Street
Lane positioning matters here
Use the left lane.
Fuel & Cost
Regular Gas
$27.35 one way
$54.70 round trip
$3.84/gal25.4 MPG avg63 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$30.02
$60.05
premium
$4.56
$32.51
$65.01
diesel
$5.61
$39.98
$79.97
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$27
Meals
$25–$50
Total
$52–$77
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 63.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $19 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
54.3
0
$19.02
$8.69
Efficient EV
45.3
0
$15.85
$7.24
EV Truck/SUV
72.4
0
$25.35
$11.59
Gas CO2
63 kg
EV CO2
21 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Brandon, MS
Late night
in Brandon on Tuesday
Local time
3:05 AM
CDT
Current temp
84°F
Unavailable
Live forecast
Destination
Amory, MS
Late night
in Amory on Tuesday
Local time
3:05 AM
CDT
Current temp
82°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 41m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
14 mi from route
~35 min detour
Free
near mile 6.2
In July, 1864, federal forces, including men from the United States Colored Troops, marched into Tupelo, Mississippi. Disorganized Confederate soldiers fought fiercely but could not overpower the fede...
24 mi from route
~59 min detour
Free
near mile 181.1
The Natchez Trace National Scenic Trail is five sections of hiking trail running roughly parallel to the 444-mile long Natchez Trace Parkway scenic motor road. The foot trails total more than 60 miles...
27 mi from route
~68 min detour
Free
near mile 181.1
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a nearly 99% highway-focused drive on this route, meaning you'll spend most of your time on well-maintained roads designed for steady travel. The longest uninterrupted stretch you'll encounter is 90 miles on MS 25, offering a good opportunity to settle in and maintain a consistent pace. While primarily a highway experience, the transition between MS 25, MS 471, and US 45 will provide slight variations in the road's feel, though always maintaining a high-speed character. This drive is less about meandering scenery and more about efficient transit.
99% highway — fuel and pacing are the main things to plan.
25 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 90 mi on MS 25.
How Hard Is This Drive?
6/10
This is a straightforward highway drive that stays mostly on MS 25 and MS 471. You will hit about 9 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.5 miles in near MS 471 / Hwy 471.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 181.1 miles you will encounter 9 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.5 miles (MS 471 / Hwy 471): Lane positioning matters here; at 112.7 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 118.9 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Brandon, MS to Amory, MS, road signs begin pointing toward Point along the way.
Point
118.9 mi in|~2h 21m|via MS 25
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 41m. Total distance: 181.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 41m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (99%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 90 miles on MS 25. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Amory, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.5 miles (MS 471 / Hwy 471): Lane positioning matters here; at 112.7 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here; at 118.9 miles (MS 25): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Yes — Medgar and Myrlie Evers Home National Monument, Tupelo National Battlefield and Natchez Trace National Scenic Trail. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.7 hours each way, an in-and-out day trip would put you behind the wheel for 7.4 hours — manageable with a long break at Amory, MS, but most travelers stay overnight.
