Saint Charles, MO to Farmington, MO is 82.5 miles and takes about 1h 41m via US 67, with a fuel budget near $12 and enough daylight to finish in a day. This trip stays within the Midwest, making it a straightforward journey through Missouri. Primarily a highway-focused drive, it’s a practical option for a quick trip or an extension of another journey. With a short duration and minimal estimated fuel cost, you can easily complete this route within a single day, offering flexibility for your schedule.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
41.3 miles from Saint Charles, MO
A natural place for your longest stop of the day
, about 51m into the drive
.
Main Roads
Road
Distance
Duration
US 67
33.6 mi
38m
I 270
19 mi
23m
Police Officer Steven Jarvis Memorial Highway
18.3 mi
19m
I 70
2.7 mi
3m
Officer Thomas G. Smith, Jr. Memorial Highway
1.8 mi
2m
MO 32
1.6 mi
2m
Rosa Parks Highway
1.5 mi
1m
South Fifth Street
1.1 mi
2m
Longest stretch:
US 67
— 33.6 mi, about 38m
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles, MO and Farmington, MO.
1
Start on North Second Street
0.2 mi·38 sec·North Second Street
2
Turn right onto Jefferson Street
0.2 mi·44 sec·Jefferson Street
3
Turn left onto MO 94
1.1 mi·2 min·South Fifth Street
Use the straight / right lanes.
4
Take the ramp
0.2 mi·14 sec
Toward I 70 EastUse the left / straight lanes.
5
Merge onto I 70
2.7 mi·3 min·I 70
6
Take the exit
0.2 mi·12 sec
Exit 232Toward I 270: Chicago, MemphisUse the slight right lane.
7
Keep slight right at fork
0.4 mi·33 sec
Toward I 270 South: MemphisUse the slight right lane.
8
Continue on this road
0.1 mi·10 sec·this road
Exit 232Toward I 270 South: Memphis
9
Merge onto I 270
19 mi·23 min·I 270
Use the straight lane.
10
Take the exit
0.4 mi·27 sec
Exit 1AToward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry RoadUse the straight / slight right lanes.
11
Keep slight right at fork
0.4 mi·43 sec
Toward I 55 South: Memphis
12
Merge onto I 55
1.5 mi·1 min·Rosa Parks Highway
13
Continue on I 55
1.8 mi·2 min·Officer Thomas G. Smith, Jr. Memorial Highway
14
Continue on I 55
18 mi·19 min·Police Officer Steven Jarvis Memorial Highway
Use the straight / slight right lanes.
15
Take the exit
0.2 mi·19 sec
Exit 174BToward US 67 South: Farmington, Poplar Bluff
16
Keep slight left at fork
0.1 mi·17 sec
17
Enter roundabout onto US 67
30 ft·0 sec·US 67
18
Continue on US 67
34 mi·38 min·US 67
19
Take the exit onto MO 32
1.6 mi·2 min·MO 32
Toward MO 32 East: Farmington
20
Turn right onto MO H
0.4 mi·1 min·North Washington Street
21
Turn right onto West Liberty Street
252 ft·13 sec·West Liberty Street
22
Turn left onto North Jefferson Street
139 ft·6 sec·North Jefferson Street
23
Arrive at destination
North Jefferson Street
Trip Plan
Given the short 1h 41m duration, this route offers plenty of flexibility, so there's no need to rush your departure. You can easily make this a same-day trip without needing multiple stops, though there are opportunities if you wish to break up the 82.5 miles. Keep an eye on your fuel gauge, as the estimated cost is low at $12, and it’s always wise to top off before heading out. A practical tip for this drive is to be aware of the shift in road type as you move from I-270 onto US 67; ensure you’re prepared for the transition.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 41.3 miles from Saint Charles, MO, or about 51m into the drive.
The longest continuous stretch on this route runs about 33.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 18 miles or 24m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 41.3 miles or 51m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 24m
Traffic, exits, and arrival timing usually matter more near Farmington, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Saint Charles, MO so your first major turns are already loaded.
Day 1
Settle into the route from Saint Charles, MO
This is one driving day of about 82.5 miles and 1h 41m.
Your first comfortable stop window is around 18 miles from Saint Charles, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 67 for about 33.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 17
5 decision points cluster between mile 0.4 and 46.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
0.4 mi into trip|~1m in|MO 94 / South Fifth Street
Turn left onto MO 94 / South Fifth Street
Lane positioning matters here
Use the straight / right lanes.
8
4.3 mi into trip|~7m in
Take the exit toward I 270: Chicago, Memphis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 232
Toward I 270: Chicago, Memphis
7
4.5 mi into trip|~8m in
Keep slight right at fork toward I 270 South: Memphis
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Toward I 270 South: Memphis
8
24.1 mi into trip|~32m in
Take the exit toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 1A
Toward I 55, US 61, US 67: Saint Louis, Memphis...
6
46.5 mi into trip|~57m in
Take the exit toward US 67 South: Farmington, Poplar Bluff
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 174B
Toward US 67 South: Farmington, Poplar Bluff
Fuel & Cost
Regular Gas
$12.90 one way
$25.80 round trip
$3.97/gal25.4 MPG avg29 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$14.16
$28.32
premium
$4.89
$15.88
$31.75
diesel
$5.61
$18.21
$36.43
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$13
Meals
$25–$50
Total
$38–$63
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 28.9 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $9 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
24.8
0
$8.66
$3.96
Efficient EV
20.6
0
$7.22
$3.30
EV Truck/SUV
33
0
$11.55
$5.28
Gas CO2
29 kg
EV CO2
10 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Saint Charles, MO
Night
in Saint Charles on Saturday
Local time
11:21 PM
CDT
Current temp
57°F
Unavailable
Live forecast
Destination
Farmington, MO
Night
in Farmington on Saturday
Local time
11:21 PM
CDT
Current temp
56°F
Unavailable
Live forecast
57°F
Imperial, MO
41 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 41m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
13 mi from route
~31 min detour
$19
near mile 22.8
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
25 mi from route
~62 min detour
Free
near mile 62.6
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route is largely highway-focused, with 69% of the drive on major highways, including stretches of US 67 and the Police Officer Steven Jarvis Memorial Highway. You'll experience a longest uninterrupted stretch of 33.6 miles on US 67, providing a consistent pace. The character of the drive is primarily about efficient travel, with the majority of your time spent on faster roadways. Expect a straightforward driving experience that prioritizes covering ground.
69% highway — fuel and pacing are the main things to plan.
23 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 33.6 mi on US 67.
How Hard Is This Drive?
10/10
This is a straightforward highway drive that stays mostly on US 67 and I 270. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.4 miles in near MO 94 / South Fifth Street.
Driving Effort10/10
Demanding - stay alert through the decision-heavy sections
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 82.5 miles you will encounter 17 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 4.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Saint Charles, MO and Farmington, MO, road signs point toward Memphis and Poplar Bluff.
Memphis
4.3 mi in|~7m
Poplar Bluff
46.5 mi in|~57m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 1h 41m. Total distance: 82.5 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 41m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (69%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 33.6 miles on US 67. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Farmington, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 4.5 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Yes — Gateway Arch National Park and Ste. Geneviève National Historical Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Farmington, MO before heading back.
