If you are planning to head inland from the coast, this 101.5-mile journey from Myrtle Beach to Cheraw is a straightforward trek across South Carolina. Expect to spend about 2 hours and 14 minutes behind the wheel, making this an easy day trip that doesn't require an overnight stay. You will primarily navigate via Church Street, US 501, and SC 38, which keeps the navigation relatively simple. Budget roughly $16 for fuel to cover the distance between these two Southeast locations. Whether you are traveling for business or a change of scenery, this route offers a practical connection between the coast and the interior of the state.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
50.8 miles from Myrtle Beach, SC
A natural place for your longest stop of the day
, about 1h 8m into the drive
.
Main Roads
Road
Distance
Duration
Church Street
30.7 mi
38m
US 501
23.4 mi
31m
SC 38
20.7 mi
28m
SC 9
12.9 mi
14m
Blenheim Highway
4.5 mi
6m
Cottingham Boulevard South
2.3 mi
2m
Highway 501 East
2 mi
3m
Broad Street
1.4 mi
2m
Longest stretch:
Church Street
— 30.7 mi, about 38m
Turn-by-Turn Driving Directions
Step-by-step road directions between Myrtle Beach, SC and Cheraw, SC.
1
Start on this road
69 ft·9 sec·this road
2
Turn left
159 ft·13 sec
3
At end of road, turn right onto US 17 Business
0.1 mi·20 sec·North Kings Highway
4
Turn left onto 6th Avenue North
489 ft·21 sec·6th Avenue North
5
Continue on 6th Avenue North
0.2 mi·46 sec·6th Avenue North
6
At end of road, turn right onto Alder Street
154 ft·6 sec·Alder Street
7
Turn left onto US 501
11 mi·16 min·US 501
Use the straight / right lanes.
8
Continue on US 501
2.0 mi·3 min·Highway 501 East
9
Continue on US 501
31 mi·38 min·Church Street
10
Take the exit onto US 501
13 mi·15 min·US 501
11
Continue on SC 38
21 mi·28 min·SC 38
12
Continue on South Main Street
0.9 mi·1 min·South Main Street
13
Continue on State Highway 38
4.5 mi·6 min·Blenheim Highway
14
Continue on State Highway 38
0.8 mi·1 min·State Highway 38
15
Continue on Broad Street
1.4 mi·2 min·Broad Street
16
Turn left onto US 15; US 401; SC 9; SC 38
0.9 mi·1 min·US 15; US 401; SC 9; SC 38
17
Turn right onto SC 9; SC 38
2.3 mi·2 min·Cottingham Boulevard South
18
Turn left onto SC 9
13 mi·14 min·SC 9
19
Turn left onto US 1 Truck; US 52 Truck
0.4 mi·28 sec·Front Street
20
Turn right onto Market Street
0.1 mi·23 sec·Market Street
21
Turn right onto US 1; US 52; SC 9
64 ft·1 sec·2nd Street
22
Arrive at destination
US 1; US 52; SC 9
Trip Plan
Since this is a relatively short drive of just over two hours, you have plenty of flexibility regarding your departure time. You can easily complete the journey without any planned stops, but keeping a steady pace will help you arrive in Cheraw in one go. Because the route relies on a mix of local roads and highways, keep an eye on your fuel gauge before leaving the Myrtle Beach area to ensure you stay within your $16 estimate. Since there are no mandatory stops listed, use the freedom of the drive to plan your own breaks along US 501 or SC 38 whenever you feel like stretching your legs. Keeping your focus on the transitions between these main roads will ensure a smooth trip.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 50.8 miles from Myrtle Beach, SC, or about 1h 8m into the drive.
The longest continuous stretch on this route runs about 30.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 22 miles or 32m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 50.8 miles or 1h 8m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 52m
Traffic, exits, and arrival timing usually matter more near Cheraw, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Myrtle Beach, SC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Myrtle Beach, SC
This is one driving day of about 101.5 miles and 2h 14m.
Your first comfortable stop window is around 22 miles from Myrtle Beach, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Church Street for about 30.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 12
5 decision points cluster between mile 0 and 101.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0 mi into trip|~0m in
Turn left
Navigation decision point
5
0 mi into trip|~0m in|US 17 Business / North Kings Highway
At end of road, turn right onto US 17 Business / North Kings Highway
Navigation decision point
4
0.2 mi into trip|~0m in|6th Avenue North
Turn left onto 6th Avenue North
Navigation decision point
5
0.4 mi into trip|~1m in|Alder Street
At end of road, turn right onto Alder Street
Navigation decision point
5
101.5 mi into trip|~2h 14m in|US 1; US 52; SC 9 / 2nd Street
Turn right onto US 1; US 52; SC 9 / 2nd Street
Navigation decision point
Fuel & Cost
Regular Gas
$15.87 one way
$31.74 round trip
$3.97/gal25.4 MPG avg36 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.34
$17.35
$34.71
premium
$4.70
$18.79
$37.57
diesel
$5.61
$22.41
$44.82
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$16
Meals
$25–$50
Total
$41–$66
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 35.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
30.5
0
$10.66
$4.87
Efficient EV
25.4
0
$8.88
$4.06
EV Truck/SUV
40.6
0
$14.21
$6.50
Gas CO2
36 kg
EV CO2
12 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Myrtle Beach, SC
Late night
in Myrtle Beach on Sunday
Local time
12:36 AM
EDT
Current temp
58°F
Unavailable
Live forecast
Destination
Cheraw, SC
Late night
in Cheraw on Sunday
Local time
12:36 AM
EDT
Current temp
82°F
Unavailable
Live forecast
74°F
Marion, SC
51 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
24 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 14m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This trip features a mixed drive profile that keeps you moving through both urban transitions and rural stretches. You will spend about 60% of your time on highways, providing a consistent pace for the majority of the trip. The longest uninterrupted section occurs early on, where you will cover 30.7 miles on Church Street. As you transition from the coastal region toward Cheraw, the character of the road shifts from busy local corridors to more open highway driving. It is a functional route that balances moderate traffic with steady cruising speeds.
60% highway — fuel and pacing are the main things to plan.
22 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 30.7 mi on Church Street.
How Hard Is This Drive?
3/10
This route mixes highway mileage with some local-road sections near the start or finish. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 2h 14m drive. You will face about 12 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start: Navigation decision point; near the start (US 17 Business / North Kings Highway): Navigation decision point; at 0.2 miles (6th Avenue North): Navigation decision point.
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 14m. Total distance: 101.5 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
The longest stretch is about 30.7 miles on Church Street. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: near the start: Navigation decision point; near the start (US 17 Business / North Kings Highway): Navigation decision point; at 0.2 miles (6th Avenue North): Navigation decision point.
Yes. A round trip is manageable in a single day if you plan a break at Cheraw, SC before heading back.
