Moss Point to Starkville is 245.3 miles and takes about 4h 48m via Mc Innis Avenue, Main Street, and Old Saracennia Road, with a fuel budget near $36 and enough daylight to finish in a day. This trip stays within Mississippi, taking you from the Southeast region to another part of the Southeast. Since this route is entirely on surface roads, expect a more local driving experience rather than high-speed highway travel. It's a straightforward drive that can easily be completed in a single day, making it ideal if you're looking for a direct connection between these two Mississippi cities.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
122.6 miles from Moss Point, MS
A natural place for your longest stop of the day
, about 2h 23m into the drive
.
Main Roads
Road
Distance
Duration
US 45
137.2 mi
2h 38m
MS 63
50.2 mi
57m
MS 57
24.2 mi
27m
US Highway 45 Alternate
18.5 mi
21m
Main Street
2.9 mi
4m
MS 182
2.2 mi
3m
MS 12
1.7 mi
2m
Mc Innis Avenue
0.3 mi
<1m
Longest stretch:
US 45
— 137.2 mi, about 2h 38m
Turn-by-Turn Driving Directions
Step-by-step road directions between Moss Point, MS and Starkville, MS.
1
Start on this road
64 ft·6 sec·this road
2
Turn right onto Mc Innis Avenue
0.3 mi·44 sec·Mc Innis Avenue
3
At end of road, turn right onto MS 613
2.9 mi·4 min·Main Street
4
Turn right
0.4 mi·36 sec
5
Continue on Old Saracennia Road
514 ft·10 sec·Old Saracennia Road
6
Turn left onto MS 63
50 mi·57 min·MS 63
7
Continue on MS 57
22 mi·24 min·MS 57
Use the straight lane.
8
Continue on MS 57
2.3 mi·2 min·MS 57
Use the straight lane.
9
Merge onto US 45
16 mi·19 min·US 45
Use the straight lane.
10
Continue on US 45
0.9 mi·1 min·US 45
Use the straight lane.
11
Continue on US 45
6.1 mi·7 min·US 45
Use the straight lane.
12
Continue on US 45
0.7 mi·49 sec·US 45
Use the straight lane.
13
Continue on US 45
1.7 mi·1 min·US 45
Use the straight lane.
14
Continue on US 45
1.8 mi·2 min·US 45
Use the straight lane.
15
Continue on US 45
6.3 mi·7 min·US 45
Use the straight lane.
16
Continue on US 45
5.6 mi·6 min·US 45
Use the straight lane.
17
Continue on US 45
3.5 mi·4 min·US 45
Use the straight lane.
18
Continue on US 45
4.7 mi·5 min·US 45
Use the straight lane.
19
Continue on US 45
5.3 mi·6 min·US 45
Use the straight lane.
20
Continue on US 45
3.7 mi·4 min·US 45
Use the straight lane.
21
Continue on US 45
1.3 mi·1 min·US 45
Use the straight lane.
22
Continue on US 45
79 mi·1 hr 30 min·US 45
Use the straight lane.
23
Keep slight left at fork onto US 45 ALT
19 mi·21 min·US Highway 45 Alternate
Toward US 45 Alternate North: West Point, TupeloUse the straight / slight left lanes.
24
Take the exit
6.6 mi·7 min
Toward US 82 West, MS 12 West, MS 25 South: Starkville
25
Take the exit
0.3 mi·50 sec
Toward MS 182 West: Starkville
26
Continue on MS 182
2.2 mi·3 min·MS 182
Use the straight / right lanes.
27
Turn left
0.2 mi·23 sec
Toward MS 12 West: AckermanUse the left lane.
28
Turn straight onto MS 12
1.7 mi·2 min·MS 12
29
Turn slight left
78 ft·5 sec
30
Turn left onto Eckford Drive
0.1 mi·34 sec·Eckford Drive
31
Continue on Victory Lane
0.2 mi·38 sec·Victory Lane
32
Turn right
214 ft·17 sec
33
Turn right
290 ft·21 sec
34
Arrive at destination
Trip Plan
For this 4h 48m drive, leaving in the morning is your best bet to maximize daylight and potentially avoid afternoon traffic. With only 1 recommended stop, you have plenty of flexibility to pace yourself. Keep an eye on your fuel gauge, as the estimated cost is $36 and finding services might be more spread out on surface roads compared to interstates. Since this is a single-day trip, you can afford to take your time and make a spontaneous stop if you see something interesting along Old Saracennia Road or Main Street.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 122.6 miles from Moss Point, MS, or about 2h 23m into the drive.
The longest continuous stretch on this route runs about 137.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 54 miles or 1h 3m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 122.6 miles or 2h 23m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 53m
Traffic, exits, and arrival timing usually matter more near Starkville, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Moss Point, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Moss Point, MS
This is one driving day of about 245.3 miles and 4h 48m.
Your first comfortable stop window is around 54 miles from Moss Point, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 45 for about 137.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 11
5 decision points cluster between mile 0.3 and 243 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.3 mi into trip|~0m in|MS 613 / Main Street
At end of road, turn right onto MS 613 / Main Street
Navigation decision point
5
78.2 mi into trip|~1h 30m in|US 45
Merge onto US 45
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
8
215.3 mi into trip|~4h 9m in|US 45 ALT / US Highway 45 Alternate
Keep slight left at fork onto US 45 ALT / US Highway 45 Alternate toward US 45 Alternate North: West Point, Tupelo
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight left lanes.
Toward US 45 Alternate North: West Point, Tupel...
5
233.9 mi into trip|~4h 31m in
Take the exit toward US 82 West, MS 12 West, MS 25 South: Starkville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 82 West, MS 12 West, MS 25 South: Sta...
7
243 mi into trip|~4h 43m in
Turn left toward MS 12 West: Ackerman
Lane positioning matters here
Use the left lane.
Toward MS 12 West: Ackerman
Fuel & Cost
Regular Gas
$38.19 one way
$76.37 round trip
$3.95/gal25.4 MPG avg86 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$42.10
$84.19
premium
$4.71
$45.50
$90.99
diesel
$6.18
$59.67
$119.35
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$38
Meals
$25–$50
Total
$63–$88
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 85.8 kg one way.
Prices: EIA weekly data, 2026-10-12.
Driving Electric?
About $26 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
73.6
0
$25.76
$11.77
Efficient EV
61.3
0
$21.46
$9.81
EV Truck/SUV
98.1
1
$34.34
$15.70
Gas CO2
86 kg
EV CO2
29 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Oct 19, 2026
Origin
Moss Point, MS
Morning
in Moss Point on Tuesday
Local time
6:32 AM
CDT
Current temp
75°F
Sunny
NE 5 to 10 mph0% chanceLive forecast
Destination
Starkville, MS
Morning
in Starkville on Tuesday
Local time
6:32 AM
CDT
Current temp
74°F
Sunny
E 5 mph0% chanceLive forecast
80°F
Quitman, MS
123 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 48m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive is entirely on surface roads, with 0% highway share. You'll be navigating local streets like Mc Innis Avenue, Main Street, and Old Saracennia Road for the full 245.3 miles. Be prepared for a consistent pace as you won't encounter any highway cruising segments. Expect to encounter local traffic and traffic signals for the entire duration of your trip.
95% highway — fuel and pacing are the main things to plan.
34 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 137.2 mi on US 45.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on US 45 and MS 63. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.3 miles in near MS 613 / Main Street.
Driving Effort5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 245.3 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.3 miles (MS 613 / Main Street): Navigation decision point; at 78.2 miles (US 45): Merge point - match speed before joining. Lane positioning matters here; at 215.3 miles (US 45 ALT / US Highway 45 Alternate): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
471 ft20 ft
Total Climb
680 ft
Total Descent
367 ft
Highest Point
471 ft
~141.5 mi in
Elevation Range
451 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Moss Point, MS to Starkville, MS, road signs begin pointing toward Tupelo along the way.
Starkville is a city in East Mississippi. Mississippi State University is located just to the east of the city limits, and is included in this article.
Top landmarks
•Odd Fellows Cemetery — African-American cemetery in Starkville, Mississippi
Doable as a same-day drive at 4h 48m. Total distance: 245.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 48m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (95%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 137.2 miles on US 45. The full list of main roads is in the Roads section above.
Yes — we found about 1 rest area or service plaza within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 0.3 miles (MS 613 / Main Street): Navigation decision point; at 78.2 miles (US 45): Merge point - match speed before joining. Lane positioning matters here; at 215.3 miles (US 45 ALT / US Highway 45 Alternate): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Possible but tiring. At 4.8 hours each way, an in-and-out day trip would put you behind the wheel for 9.6 hours — manageable with a long break at Starkville, MS, but most travelers stay overnight.
