Connecting Greenville to Philadelphia, this 149.2-mile journey takes you across the heart of Mississippi in approximately 3 hours and 30 minutes. Since the drive is entirely within the Southeast region, you can expect a consistent atmosphere as you transition between these two inland cities. Given the manageable duration, this trip is perfectly suited for a single-day excursion, allowing you to reach your destination without needing an overnight stay. Expect to budget roughly $23 for fuel to cover the distance. Navigating via US 82, MS 35, and MS 14, you will find this route offers a straightforward path for travelers looking to move efficiently between these points. It is a practical choice if you prioritize a direct route over a leisurely multi-day tour.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
74.6 miles from Greenville, MS
A natural place for your longest stop of the day
, about 1h 37m into the drive
.
Main Roads
Road
Distance
Duration
US 82
61.6 mi
1h 17m
MS 35
37.7 mi
56m
MS 14
34.9 mi
52m
MS 182
9.2 mi
13m
Pecan Avenue
1.8 mi
2m
South Huntington Street
1.4 mi
2m
Veterans Memorial Drive
1.1 mi
1m
Main Street
0.9 mi
2m
Longest stretch:
US 82
— 61.6 mi, about 1h 17m
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville, MS and Philadelphia, MS.
1
Start on MS 814
10 ft·7 sec·South Broadway Street
2
Turn left onto Main Street
0.9 mi·2 min·Main Street
3
Turn left onto MS 182
9.2 mi·13 min·MS 182
4
Turn left onto US 82; US 278
37 mi·44 min·US 82; US 278
Use the straight lane.
5
Continue on US 82; MS 7
25 mi·33 min·US 82; MS 7
6
Turn right onto MS 35
38 mi·56 min·MS 35
7
Turn left onto East Jefferson Street
0.1 mi·15 sec·East Jefferson Street
8
Turn right onto South Huntington Street
1.4 mi·2 min·South Huntington Street
9
Turn right onto MS 19; MS 35
1.1 mi·1 min·Veterans Memorial Drive
10
Turn left onto MS 14; MS 19
35 mi·52 min·MS 14; MS 19
11
At end of road, turn right onto Pecan Avenue
1.8 mi·2 min·Pecan Avenue
12
Turn right onto MS 16; MS 19; MS 21
0.5 mi·48 sec·West Beacon Street
13
Turn left onto Front Street
60 ft·2 sec·Front Street
14
Arrive at destination
Front Street
Trip Plan
Because this route is relatively short, you have the flexibility to depart whenever fits your schedule best. Plan for at least one stop during your 3.5-hour drive to stretch your legs and refresh, especially since the vast majority of the mileage is spent on highways. Keep an eye on your fuel gauge during the initial 61.6-mile stretch on US 82, as this is your longest period of continuous driving. Since you are only making one stop, try to time it for the transition between US 82 and the state highways to break up the monotony of the longer road sections. Being prepared for a straightforward, highway-heavy trip will help you complete the 149.2-mile journey comfortably in one go.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 74.6 miles from Greenville, MS, or about 1h 37m into the drive.
The longest continuous stretch on this route runs about 61.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 33 miles or 43m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 74.6 miles or 1h 37m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 50m
Traffic, exits, and arrival timing usually matter more near Philadelphia, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Greenville, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Greenville, MS
This is one driving day of about 149.2 miles and 3h 30m.
Your first comfortable stop window is around 33 miles from Greenville, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 82 for about 61.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 11
5 decision points cluster between mile 0 and 146.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0 mi into trip|~0m in|Main Street
Turn left onto Main Street
Navigation decision point
4
0.9 mi into trip|~2m in|MS 182
Turn left onto MS 182
Navigation decision point
4
10.1 mi into trip|~16m in|US 82; US 278
Turn left onto US 82; US 278
Lane positioning matters here
Use the straight lane.
4
109.5 mi into trip|~2h 30m in|South Huntington Street
Turn right onto South Huntington Street
Navigation decision point
5
146.9 mi into trip|~3h 26m in|Pecan Avenue
At end of road, turn right onto Pecan Avenue
Navigation decision point
Fuel & Cost
Regular Gas
$22.53 one way
$45.07 round trip
$3.84/gal25.4 MPG avg52 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$24.74
$49.47
premium
$4.56
$26.78
$53.56
diesel
$5.61
$32.94
$65.88
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$23
Meals
$25–$50
Total
$48–$73
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 52.2 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $16 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
44.8
0
$15.67
$7.16
Efficient EV
37.3
0
$13.05
$5.97
EV Truck/SUV
59.7
0
$20.89
$9.55
Gas CO2
52 kg
EV CO2
17 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Greenville, MS
Night
in Greenville on Saturday
Local time
11:35 PM
CDT
Current temp
77°F
Unavailable
Live forecast
Destination
Philadelphia, MS
Night
in Philadelphia on Saturday
Local time
11:35 PM
CDT
Current temp
79°F
Unavailable
Live forecast
52°F
Winona, MS
75 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 30m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive is heavily highway-focused, with 96% of your journey spent on high-speed roads. You will settle into a steady rhythm early on, as the longest uninterrupted stretch spans 61.6 miles along US 82. The experience is primarily defined by open highway travel, providing a consistent pace that keeps your arrival time predictable. While you will eventually transition onto MS 35 and MS 14, the overall personality of the route remains utilitarian and efficient. Expect a drive that favors speed and directness rather than winding, technical roads, making it a reliable option for those who want to cover the 149.2 miles without significant delays.
96% highway — fuel and pacing are the main things to plan.
14 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 61.6 mi on US 82.
How Hard Is This Drive?
2/10
This is a straightforward highway drive that stays mostly on US 82 and MS 35. Navigation is very simple - set it and forget it for most of the drive. The trickiest moment comes early in the drive near Main Street.
Driving Effort2/10
Very easy - short and simple to drive
Balances navigation complexity with total wheel time.
The drive from Greenville, MS to Philadelphia, MS is easy. At 3h 30m with 96% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
The main spots that need attention: near the start (Main Street): Navigation decision point; at 0.9 miles (MS 182): Navigation decision point; at 10.1 miles (US 82; US 278): Lane positioning matters here.
Greenville is a city in Washington County, Mississippi, United States. The population was 30,000 in 2020, making it the ninth largest city in the state. It is the county seat of Washington County.
The longest stretch is about 61.6 miles on US 82. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: near the start (Main Street): Navigation decision point; at 0.9 miles (MS 182): Navigation decision point; at 10.1 miles (US 82; US 278): Lane positioning matters here.
Possible but tiring. At 3.5 hours each way, an in-and-out day trip would put you behind the wheel for 7.0 hours — manageable with a long break at Philadelphia, MS, but most travelers stay overnight.
