Gladstone, MO to Saint Charles, MO is 234.9 miles and takes about 4h 36m via Dwight D. Eisenhower Highway, with a fuel budget near $37 and enough daylight to finish in a day. This drive stays within Missouri, connecting two points in the Midwest. Given that it's mostly surface roads, expect a relaxed pace rather than high-speed cruising. The route is designed for a single day, making it a convenient option for a quick trip between these two locations.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
117.4 miles from Gladstone, MO
A natural place for your longest stop of the day
, about 2h 14m into the drive
.
Main Roads
Road
Distance
Duration
Dwight D. Eisenhower Highway
153.3 mi
2h 56m
U.S. Submarine Veterans' Memorial Highway
54.4 mi
58m
Truman/Eisenhower Presidential Highway
5.6 mi
6m
Lamar Hunt Memorial Highway
4.4 mi
5m
Sheriff Roger I. Wilson Memorial Highway
1.9 mi
2m
Clifton J. Scott Memorial Highway
1.8 mi
2m
Northeast Chouteau Trafficway
1.7 mi
3m
North Chouteau Trafficway
1.7 mi
2m
Longest stretch:
Dwight D. Eisenhower Highway
— 153.3 mi, about 2h 56m
Traffic on I-70
Hour-of-day weekday pattern from 27 FHWA count stations on your route.
Peak
4 PM
~2,893 veh/hr typical
· worst 3,398
Quietest
1 AM
~270 veh/hr
Peak-to-quiet ratio
10.7×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Gladstone, MO and Saint Charles, MO.
1
Start on North Garfield Avenue
413 ft·20 sec·North Garfield Avenue
2
Turn right onto Northeast 61st Street
0.3 mi·1 min·Northeast 61st Street
3
Turn right onto MO 1
0.7 mi·1 min·North Antioch Road
Use the straight / right lanes.
4
Turn left onto Northeast Chouteau Trafficway
1.7 mi·3 min·Northeast Chouteau Trafficway
Use the left lane.
5
Continue on MO 269
1.6 mi·2 min·Northeast Chouteau Parkway
6
Continue on MO 269
1.7 mi·2 min·North Chouteau Trafficway
7
Turn left onto East Front Street
1.2 mi·2 min·East Front Street
8
Take the ramp
0.3 mi·33 sec
Toward I 435 South: Grandview
9
Merge onto I 435
4.4 mi·5 min·Lamar Hunt Memorial Highway
10
Keep slight right at fork onto US 24
0.3 mi·23 sec·US 24
Exit 63Toward I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex
11
Keep slight left at fork
1.2 mi·1 min
Toward I 70 East: Saint LouisUse the straight / slight right lanes.
12
Keep slight left at fork
469 ft·11 sec
Toward I 70 East: Saint LouisUse the slight left / straight lanes.
32 mi·34 min·U.S. Submarine Veterans' Memorial Highway
19
Keep slight left at fork onto I 70
22 mi·24 min·U.S. Submarine Veterans' Memorial Highway
20
Continue on I 70; US 40
1.8 mi·2 min·Dwight D. Eisenhower Highway
21
Continue on I 70; US 40
1.6 mi·1 min·Highway Patrol Sgt. Benjamin Booth Memorial Highway
22
Continue on I 70; US 40
1.9 mi·2 min·Sheriff Roger I. Wilson Memorial Highway
23
Continue on I 70; US 40
99 mi·1 hr 57 min·Dwight D. Eisenhower Highway
Use the straight / slight right lanes.
24
Take the exit
0.1 mi·14 sec
Exit 228Toward I 70 Business, MO 94: First Capitol Drive, Lewis and Clark TrailUse the slight right lane.
25
Keep slight left at fork
0.1 mi·14 sec
Toward I 70 Business, MO 94 East: First Capitol Drive, Lindenwood University, SSM Health Saint Joseph HospitalUse the slight left / slight right lanes.
26
Turn straight onto I 70 Business; MO 94
0.9 mi·2 min·First Capitol Drive
27
Turn slight right onto I 70 Business; MO 94
0.9 mi·2 min·I 70 Business; MO 94
Toward MO 94
28
Turn left onto South Second Street
0.3 mi·56 sec·South Second Street
29
Arrive at destination
North Second Street
Trip Plan
With a duration of under five hours, this trip is easily manageable in a single day, so you can leave whenever it suits you. Consider departing in the morning to maximize daylight for the 234.9-mile drive. Since most of the route is on surface roads, keep an eye out for frequent traffic signals and local speed limits. The estimated fuel cost is around $37, so be sure to check your tank before you head out, especially given the 153.3-mile highway segment where stops might be less frequent.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 117.4 miles from Gladstone, MO, or about 2h 14m into the drive.
The longest continuous stretch on this route runs about 153.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 52 miles or 1h 4m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 117.4 miles or 2h 14m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 43m
Traffic, exits, and arrival timing usually matter more near Saint Charles, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Gladstone, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Gladstone, MO
This is one driving day of about 234.9 miles and 4h 36m.
Your first comfortable stop window is around 52 miles from Gladstone, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D. Eisenhower Highway for about 153.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 14
5 decision points cluster between mile 11.9 and 232.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
11.9 mi into trip|~20m in|US 24
Keep slight right at fork onto US 24 toward I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Exit 63
Toward I 70, US 24 West, US 40: Saint Louis, Ka...
7
12.2 mi into trip|~20m in
Keep slight left at fork toward I 70 East: Saint Louis
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward I 70 East: Saint Louis
7
13.4 mi into trip|~22m in
Keep slight left at fork toward I 70 East: Saint Louis
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left / straight lanes.
Toward I 70 East: Saint Louis
8
232.5 mi into trip|~4h 30m in
Take the exit toward I 70 Business, MO 94: First Capitol Drive, Lewis and Clark Trail
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 228
Toward I 70 Business, MO 94: First Capitol Driv...
9
232.7 mi into trip|~4h 30m in
Keep slight left at fork toward I 70 Business, MO 94 East: First Capitol Drive, Lindenwood University, SSM Health Saint Joseph Hospital
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward I 70 Business, MO 94 East: First Capitol...
Fuel & Cost
Regular Gas
$34.69 one way
$69.38 round trip
$3.75/gal25.4 MPG avg82 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.14
$38.30
$76.59
premium
$4.72
$43.61
$87.23
diesel
$4.80
$44.35
$88.71
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$35
Meals
$25–$50
Total
$60–$85
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 82.2 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $25 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
70.5
0
$24.66
$11.28
Efficient EV
58.7
0
$20.55
$9.40
EV Truck/SUV
94
1
$32.89
$15.03
Gas CO2
82 kg
EV CO2
27 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 18, 2026
Origin
Gladstone, MO
Late night
in Gladstone on Sunday
Local time
5:35 AM
CDT
Current temp
92°F
Slight Chance Rain Showers then Slight Chance Showers And Thunderstorms
SW 8 mph20% chanceLive forecast
Heat Advisory
Heat Advisory issued July 18 at 10:43AM CDT until July 21 at 7:00PM CDT by NWS Paducah KY
Heat Advisory
Heat Advisory issued July 18 at 9:57AM CDT until July 18 at 7:00PM CDT by NWS Quad Cities IA IL
Destination
Saint Charles, MO
Late night
in Saint Charles on Sunday
Local time
5:35 AM
CDT
Current temp
94°F
Mostly Sunny
W 10 mph7% chanceLive forecast
Heat Advisory
Heat Advisory issued July 18 at 10:43AM CDT until July 21 at 7:00PM CDT by NWS Paducah KY
Heat Advisory
Heat Advisory issued July 18 at 9:57AM CDT until July 18 at 7:00PM CDT by NWS Quad Cities IA IL
91°F
Columbia, MO
117 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 36m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
19 mi from route
~48 min detour
$19
near mile 234.9
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
You'll spend most of your time on surface roads, with the highway comprising 100% of the route. The longest continuous stretch on a highway is 153.3 miles on Dwight D. Eisenhower Highway. As you transition from highway to surface roads, be prepared for more frequent intersections and a change in speed.
Only 1% highway — the rest is turn-by-turn surface driving.
29 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 153.3 mi on Dwight D. Eisenhower Highway.
How Hard Is This Drive?
8/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 11.9 miles in near US 24.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 234.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 11.9 miles (US 24): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 12.2 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 13.4 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Elevation Profile
Mostly flat terrain
949 ft491 ft
Total Climb
523 ft
Total Descent
969 ft
Highest Point
949 ft
~16.8 mi in
Elevation Range
458 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Gladstone, MO and Saint Charles, MO, road signs point toward Kansas City and Sports Complex.
St. Charles, Missouri is outside of St. Louis on the bank of the Missouri River. It was Missouri's first state capital and was one of the first stops by Lewis and Clark on their journey to explore Louisiana Territory. The historic Main Street has largely been restored to its 1812-era appearance including gas lights a boardwalk and is lined with shops selling artwork, handicrafts, home decorations, antiques. There are also many restaurants.
Top landmarks
•First Missouri State Capitol State Historic Site — historic site in Missouri, United States
•African Church — church building in Missouri, United States of America
•Frenchtown Historic District — historic district in St. Charles County, Missouri
Doable as a same-day drive at 4h 36m. Total distance: 234.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 36m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 153.3 miles on Dwight D. Eisenhower Highway. The full list of main roads is in the Roads section above.
Yes — we found about 36 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Saint Charles, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 36 rest areas along the route for bathroom stops.
The main spots that need attention: at 11.9 miles (US 24): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 12.2 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 13.4 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Yes — Gateway Arch National Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.6 hours each way, an in-and-out day trip would put you behind the wheel for 9.2 hours — manageable with a long break at Saint Charles, MO, but most travelers stay overnight.
