East Independence, MO to New Madrid, MO is 387.6 miles and takes about 7h 21m via Police Officer Steven Jarvis Memorial Highway, Dwight D. Eisenhower Highway, and U.S. Submarine Veterans' Memorial Highway, with a fuel budget near $61 and enough daylight to finish in a day. This trip stays entirely within Missouri, moving from the Midwest region to another part of the Midwest. Given its mostly surface road profile, expect a more relaxed pace than a pure interstate cruise. This route is a solid option if you're looking for a single-day drive with a manageable fuel cost and a clear destination.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
193.8 miles from East Independence, MO
A natural place for your longest stop of the day
, about 3h 43m into the drive
.
Main Roads
Road
Distance
Duration
Police Officer Steven Jarvis Memorial Highway
143.3 mi
2h 33m
Dwight D. Eisenhower Highway
135.3 mi
2h 34m
U.S. Submarine Veterans' Memorial Highway
54.4 mi
58m
Avenue of the Saints
25.1 mi
30m
I 270
11.5 mi
14m
I 55 Bus
2.7 mi
4m
Sheriff Roger I. Wilson Memorial Highway
1.9 mi
2m
Officer Thomas G. Smith, Jr. Memorial Highway
1.8 mi
2m
Longest stretch:
Police Officer Steven Jarvis Memorial Highway
— 143.3 mi, about 2h 33m
Turn-by-Turn Driving Directions
Step-by-step road directions between East Independence, MO and New Madrid, MO.
1
Start on East 9th Street South
79 ft·8 sec·East 9th Street South
2
Turn left onto Main Road
0.3 mi·1 min·Main Road
3
Turn left onto East Truman Road
0.7 mi·1 min·East Truman Road
4
Turn right onto Holke Road
0.9 mi·1 min·Holke Road
5
Turn straight onto South Jackson Drive
1.2 mi·2 min·South Jackson Drive
6
Turn left onto East R.D. Mize Road
0.2 mi·37 sec·East R.D. Mize Road
7
Turn right onto South Little Blue Parkway
1.7 mi·3 min·South Little Blue Parkway
8
Take the ramp
0.3 mi·38 sec
Exit 17Toward Little Blue Parkway, 39th Street, Mall EntranceUse the left lane.
9
Continue on I 70
53 mi·56 min·Dwight D. Eisenhower Highway
10
Continue on I 70; US 40
32 mi·34 min·U.S. Submarine Veterans' Memorial Highway
11
Keep slight left at fork onto I 70
22 mi·24 min·U.S. Submarine Veterans' Memorial Highway
12
Continue on I 70; US 40
1.8 mi·2 min·Dwight D. Eisenhower Highway
13
Continue on I 70; US 40
1.6 mi·1 min·Highway Patrol Sgt. Benjamin Booth Memorial Highway
14
Continue on I 70; US 40
1.9 mi·2 min·Sheriff Roger I. Wilson Memorial Highway
15
Continue on I 70; US 40
81 mi·1 hr 35 min·Dwight D. Eisenhower Highway
16
Take the exit onto US 40
0.3 mi·33 sec·US 40
Exit 210AToward I 64 East, US 40 East, US 61 South: Chesterfield
17
Merge onto I 64; US 40; US 61
25 mi·30 min·Avenue of the Saints
Use the straight / slight left lanes.
18
Take the exit
0.3 mi·38 sec
Exit 25Toward I 270: Chicago, MemphisUse the slight right lane.
19
Keep slight right at fork
0.3 mi·31 sec
Toward I 270 South: MemphisUse the slight right lane.
20
Merge onto I 270
11 mi·14 min·I 270
Use the straight lane.
21
Take the exit
0.4 mi·27 sec
Exit 1AToward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry RoadUse the straight / slight right lanes.
22
Keep slight right at fork
0.4 mi·43 sec
Toward I 55 South: Memphis
23
Merge onto I 55
1.5 mi·1 min·Rosa Parks Highway
24
Continue on I 55
1.8 mi·2 min·Officer Thomas G. Smith, Jr. Memorial Highway
25
Continue on I 55
143 mi·2 hr 33 min·Police Officer Steven Jarvis Memorial Highway
Use the straight / slight right lanes.
26
Take the exit
0.2 mi·24 sec
Exit 49Toward US 61, US 62, I 55 Business: New Madrid
27
Turn left onto I 55 Bus; US 61; US 62
2.7 mi·4 min·I 55 Bus; US 61; US 62
28
Turn left onto MO U
0.2 mi·25 sec·Dawson Road
29
Turn right onto Kings Highway
0.8 mi·2 min·Kings Highway
30
Turn left onto Mill Street
0.3 mi·47 sec·Mill Street
31
Turn left
92 ft·6 sec
32
Arrive at destination
Trip Plan
For this 7-hour drive, leaving in the morning around 8 or 9 AM should give you ample time to reach New Madrid before evening. With two recommended stops, you can plan for a break roughly every two to three hours to stretch your legs and refuel. The longest stretch on a highway is over 143 miles, so consider making your first stop after that segment. Keep an eye on your fuel gauge, as the $61 budget is an estimate and actual costs can vary. Given it's a single-day trip, you have flexibility, but staying aware of the transition from highways to surface roads will help you anticipate changes in driving speed and traffic.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 193.8 miles from East Independence, MO, or about 3h 43m into the drive.
The longest continuous stretch on this route runs about 143.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 85 miles or 1h 37m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 193.8 miles or 3h 43m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 6h 14m
Traffic, exits, and arrival timing usually matter more near New Madrid, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving East Independence, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from East Independence, MO
This is one driving day of about 387.6 miles and 7h 21m.
Your first comfortable stop window is around 85 miles from East Independence, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on Police Officer Steven Jarvis Memorial Highway for about 143.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 21
5 decision points cluster between mile 5 and 236 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
8
5 mi into trip|~10m in
Take the ramp toward Little Blue Parkway, 39th Street, Mall Entrance
Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Exit 17
Toward Little Blue Parkway, 39th Street, Mall E...
6
198.5 mi into trip|~3h 48m in|US 40
Take the exit onto US 40 toward I 64 East, US 40 East, US 61 South: Chesterfield
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 210A
Toward I 64 East, US 40 East, US 61 South: Ches...
8
223.9 mi into trip|~4h 19m in
Take the exit toward I 270: Chicago, Memphis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 25
Toward I 270: Chicago, Memphis
7
224.2 mi into trip|~4h 20m in
Keep slight right at fork toward I 270 South: Memphis
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Toward I 270 South: Memphis
8
236 mi into trip|~4h 35m in
Take the exit toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 1A
Toward I 55, US 61, US 67: Saint Louis, Memphis...
Fuel & Cost
Regular Gas
$60.60 one way
$121.19 round trip
$3.97/gal25.4 MPG avg136 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$66.53
$133.07
premium
$4.89
$74.59
$149.18
diesel
$5.61
$85.58
$171.15
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$61
Meals
$25–$50
Total
$86–$111
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 135.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
EV Charging Along Route
29 DC fast chargers
· Coverage: excellent
Stoney Creek Hotel & Conference Center - Tesla Supercharger
Independence, MO
Tesla
14 DCFC
Hy-Vee - Tesla Supercharger
Columbia, MO
Tesla
12 DCFC
Blue Springs, MO Rechargery Relay - NE Coronado
Blue Springs, MO
IONNA
10 DCFC
Casey's General Store - Tesla Supercharger
Concordia, MO
Tesla
8 DCFC
Bandana's BBQ - Tesla Supercharger
Columbia, MO
Tesla
8 DCFC
The Holiday Inn - Columbia East - Tesla Supercharger
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $41 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
116.3
1
$40.70
$18.60
Efficient EV
96.9
1
$33.92
$15.50
EV Truck/SUV
155
1
$54.26
$24.81
Gas CO2
136 kg
EV CO2
45 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 19, 2026
Origin
East Independence, MO
Late night
in East Independence on Sunday
Local time
3:00 AM
CDT
Current temp
40°F
Mostly Clear
WSW 3 mph0% chanceLive forecast
Flood Warning
Flood Warning issued April 18 at 8:47PM CDT by NWS St Louis MO
Flood Warning
Flood Warning issued April 18 at 8:47PM CDT by NWS St Louis MO
Destination
New Madrid, MO
Late night
in New Madrid on Sunday
Local time
3:00 AM
CDT
Current temp
41°F
Mostly Clear
NW 1 to 5 mph0% chanceLive forecast
Flood Warning
Flood Warning issued April 18 at 8:47PM CDT by NWS St Louis MO
Flood Warning
Flood Warning issued April 18 at 8:47PM CDT by NWS St Louis MO
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
7h 21m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Ste. Geneviève National Historical Park
National Historical Park
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
6 mi from route
~16 min detour
Free
near mile 280.7
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
14 mi from route
~36 min detour
$19
near mile 227.2
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This drive is mostly on surface roads, with highways making up about 40% of the route. You'll spend the longest stretch, 143.3 miles, on the Police Officer Steven Jarvis Memorial Highway. After the highway segments, expect to transition to surface roads for a significant portion of your travel. This means you'll likely encounter more local traffic and potentially more intersections as you get closer to your destination.
Only 4% highway — the rest is turn-by-turn surface driving.
32 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 143.3 mi on Police Officer Steven Jarvis Memorial Highway.
How Hard Is This Drive?
9/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 5 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 21 significant decision points across 387.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 5 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 198.5 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 223.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from East Independence, MO to New Madrid, MO, road signs begin pointing toward Memphis along the way.
Memphis
223.9 mi in|~4h 19m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 7h 21m. Total distance: 387.6 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 21m drive, plan rest stops for pacing.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 143.3 miles on Police Officer Steven Jarvis Memorial Highway. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at New Madrid, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 5 miles: Lane positioning matters here. Multiple destination signs - pick the right one; at 198.5 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 223.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Not recommended in a single day. At 7.4 hours each way, a round trip means 14.7 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at New Madrid, MO before the return drive.
