Origin
De Soto, MO
Late night in De Soto on Tuesday
Local time
4:21 AM
CDT
Current temp
73°F
Unavailable
Live forecast
Trip from De Soto, MO to St. Louis, MO
Pin this tripCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
59m
Distance
47 mi
76 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$7
one way
EV Charging
Unknown
Best Time to Leave
4 AM
0h 54m
★
6 AM
0h 59m
8 AM
1h 9m
10 AM
1h 3m
12 PM
1h 2m
3 PM
1h 3m
5 PM
1h 8m
8 PM
0h 56m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
De Soto, MO
Wikimedia Commons
Trip Overview
De Soto, MO to St. Louis, MO is 47 miles and takes about 59 minutes via I 55 and US 67, with a fuel budget near $7 and enough daylight to finish in a day. This short trip stays within the Midwest, making it a straightforward hop between two points in Missouri. The drive is primarily highway-focused, offering a quick and efficient way to get from your starting point to your destination. You'll be on major roads for most of the journey, so expect typical highway conditions. Given its brevity, this route is ideal for a same-day excursion with plenty of time to spare.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 55 | 20.5 mi | 22m |
| Rosa Parks Highway | 12.5 mi | 15m |
| US 67 | 6 mi | 7m |
| MO 110 | 4.2 mi | 5m |
| South Tucker Boulevard | 1.3 mi | 3m |
| Fountain City Road | 0.8 mi | 1m |
| North Main Street | 0.6 mi | <1m |
| Gravois Avenue | 0.2 mi | <1m |
Longest stretch:
I 55
— 20.5 mi, about 22m
Turn-by-Turn Driving Directions
Step-by-step road directions between De Soto, MO and St. Louis, MO.
1
Start on Easton Street
435 ft
·
24 sec
·
Easton Street
2
At end of road, turn left onto North Main Street
0.6 mi
·
57 sec
·
North Main Street
3
Turn right onto Fountain City Road
0.8 mi
·
1 min
·
Fountain City Road
4
Turn right onto MO 110
4.2 mi
·
5 min
·
MO 110
5
Take the ramp
0.3 mi
·
18 sec
Toward US 67 North: Festus, Crystal City
6
Merge onto US 67
5.7 mi
·
6 min
·
US 67
7
Keep slight right at fork onto US 67
0.3 mi
·
27 sec
·
US 67
8
Take the exit
0.3 mi
·
49 sec
Toward I 55 North: Saint Louis
9
Merge onto I 55
21 mi
·
22 min
·
I 55
10
Continue on I 55
12 mi
·
15 min
·
Rosa Parks Highway
Use the straight / slight right lanes.
11
Take the exit
0.2 mi
·
23 sec
Exit 207A
Toward MO 30 East: Gravois Avenue
Use the slight right lane.
12
Turn slight right onto Gravois Avenue
0.2 mi
·
27 sec
·
Gravois Avenue
13
Continue on South Tucker Boulevard
1.3 mi
·
3 min
·
South Tucker Boulevard
14
Turn right onto Market Street
86 ft
·
2 sec
·
Market Street
15
Arrive at destination
Market Street
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
24 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 10 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 23.5 miles from De Soto, MO, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 95 decision points cluster between mile 0.1 and 45.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0.1 mi into trip
|
~0m in
|
North Main Street
At end of road, turn left onto North Main Street
Navigation decision point
5
5.7 mi into trip
|
~8m in
Take the ramp toward US 67 North: Festus, Crystal City
Multiple destination signs - pick the right one
Toward US 67 North: Festus, Crystal City
4
11.6 mi into trip
|
~15m in
|
US 67
Keep slight right at fork onto US 67
Highway fork - watch signs carefully
4
11.9 mi into trip
|
~16m in
Take the exit toward I 55 North: Saint Louis
Exit ramp - move to the correct lane early
Toward I 55 North: Saint Louis
7
45.3 mi into trip
|
~54m in
Take the exit toward MO 30 East: Gravois Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 207A
Toward MO 30 East: Gravois Avenue
Fuel & Cost
Regular Gas
$7.35 one way
$14.70 round trip
$3.97/gal
25.4 MPG avg
16 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $8.07 | $16.14 |
| premium | $4.89 | $9.04 | $18.09 |
| diesel | $5.61 | $10.38 | $20.75 |
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$7
Estimated CO2 emission: 16.4 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $5 in charging · 0 stops · 69% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 14.1 | 0 | $4.94 | $2.26 |
| Efficient EV | 11.8 | 0 | $4.11 | $1.88 |
| EV Truck/SUV | 18.8 | 0 | $6.58 | $3.01 |
Gas CO2
16 kg
EV CO2
5 kg (69% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
St. Louis, MO
Late night in St. Louis on Tuesday
Local time
4:21 AM
CDT
Current temp
70°F
Unavailable
Live forecast
73°F
Imperial, MO
24 mi in
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
3 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
59m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
What kind of drive is this?
This is a highway-focused drive, with about 65% of the route utilizing major highways like I 55 and US 67. You'll experience a significant uninterrupted stretch of 20.5 miles on I 55, which means consistent speed and minimal interruptions for a good portion of the trip. The overall character is one of efficient travel, designed to get you between destinations without much fuss. Expect standard interstate driving conditions for the majority of the 47 miles.
65% highway — fuel and pacing are the main things to plan.
15 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 20.5 mi on I 55.
How Hard Is This Drive?
6/10
This is a straightforward highway drive that stays mostly on I 55 and Rosa Parks Highway. You will hit about 9 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.1 miles in near North Main Street.
Driving Effort
6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 47 miles you will encounter 9 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (North Main Street): Navigation decision point; at 5.7 miles: Multiple destination signs - pick the right one; at 11.6 miles (US 67): Highway fork - watch signs carefully.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from De Soto, MO to St. Louis, MO, road signs begin pointing toward Crystal City along the way.
Crystal City
5.7 mi in
|
~8m
About the Cities
Arriving in St. Louis, MO
Full guide →The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. The city's planners have created an aesthetically beautiful city, with plenty of green space amidst buildings both old and new, framed by the majestic Mississippi and Missouri rivers. And capping it all is the world's tallest man-made monument, the beautiful and iconic Gateway Arch. St. Louis is a city of culture and surprisingly inexpensive. Among American cities, only Washington, D.C. has more free attractions for tourists and residents alike. Hotels, restaurants, and even parking garages avoid the premium pricing common in other big cities. Although often overlooked, St. Louis can be an affordable, educational, and fun family getaway.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 59m. Total distance: 47 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
59m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (65%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 20.5 miles on I 55. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at St. Louis, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 0.1 miles (North Main Street): Navigation decision point; at 5.7 miles: Multiple destination signs - pick the right one; at 11.6 miles (US 67): Highway fork - watch signs carefully.
Yes — Gateway Arch National Park and Ste. Geneviève National Historical Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at St. Louis, MO before heading back.
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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