Cafe de Blaire
Near the end, right off the route
St. Louis, Missouri
Hours: 7 am–7 pm
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
3h 58m
Distance
193.3 mi
311 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$30
one way
EV Charging
Good
8 stations
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Cole Camp, MO
Wikimedia Commons
This 193.9-mile journey from Cole Camp, MO, to St. Louis, MO, is an achievable day trip, estimated to take around 3 hours and 14 minutes of driving time. The route primarily utilizes East Main Street, Southwest Boulevard, and US 54 East, with no highway driving, suggesting a more local road experience. With an estimated fuel cost of $29, this drive offers an economical way to travel between two points within the Midwest region. The single recommended stop allows for flexibility in planning your travel day. Given its manageable distance and duration, it's well-suited for a single-day adventure without the need for an overnight stay.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
96.6 miles from Cole Camp, MO
A natural place for your longest stop of the day , about 2h 2m into the drive .
| Road | Distance | Duration |
|---|---|---|
| Dwight D. Eisenhower Highway | 61.9 mi | 1h 11m |
| MO C | 35 mi | 47m |
| C. F. “Red” Whaley Expressway | 31.9 mi | 35m |
| Avenue of the Saints | 27.7 mi | 33m |
| East Main Street | 20.2 mi | 27m |
| Jack Buck Memorial Highway | 5.8 mi | 7m |
| Daniel Boone Expressway | 5.7 mi | 7m |
| MO 5 | 3.4 mi | 4m |
Step-by-step road directions between Cole Camp, MO and St. Louis, MO.
Start on South Maple Street
Turn right onto MO 52
Keep slight left at fork
Keep slight right at fork onto MO 5; MO 52
Turn left onto MO C
Turn right
Turn left
Turn straight onto MO C
Turn right onto MO C
Take the ramp
Merge onto US 54
Take the exit
Merge onto I 70; US 40
Take the exit onto US 40
Merge onto I 64; US 40; US 61
Continue on I 64; US 40
Continue on I 64; US 40
Take the exit
Turn left onto South 14th Street
Turn right onto Market Street
Arrive at destination
For this 3-hour and 14-minute drive, consider an early morning departure from Cole Camp to maximize your daylight and flexibility. Since there's only one recommended stop and no highway stretches, you can easily pace yourself with brief breaks as needed. The estimated fuel cost of $29 is quite reasonable, so ensure your tank is full before you leave Cole Camp. Keep an eye out for the transitions in road types as you move from local streets onto US 54 East, as this will likely be the most significant change in driving character along the 193.9-mile route.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 43 miles or 58m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 96.6 miles or 2h 2m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 14m
Traffic, exits, and arrival timing usually matter more near St. Louis, MO than in the middle of the route.
Open the route before leaving Cole Camp, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Cole Camp, MO
This is one driving day of about 193.3 miles and 3h 58m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
97 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 43 miles helps settle the day before fatigue starts building.
The midpoint is around 96.6 miles from Cole Camp, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 61.9 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Best meal stop · home stretch
St. Louis, Missouri
Near the end, right off the route
Hours: 7 am–7 pm
Vicini pastaria, cafe, & market
St. Louis, Missouri
Mayo Ketchup
St. Louis, Missouri
Best coffee break · home stretch
St. Louis, Missouri
Near the end, right off the route
Hours: 6:30 am–3 pm
+13149402333
Protagonist Cafe
St. Louis, Missouri
Soulard Cafe
St. Louis, Missouri
Near the end, right off the route
St. Louis, Missouri
Hours: 7 am–7 pm
Near the end, short detour
St. Louis, Missouri
Hours: 11:30 am–6 pm
+13148276150
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 11 am–8 pm
+13146962699
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 7 am–2 pm
+13144058178
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 5–9:30 pm
+13147715777
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 5–10 pm
+13147738646
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 8 am–7 pm
+13145719009
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 11 am–8 pm
+13148750034
Visit websiteNear the end, right off the route
St. Louis, Missouri
Hours: 6:30 am–3 pm
+13149402333
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 7 am–7 pm
+13148333085
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 8 am–3 pm
+13142408809
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 10 am–5 pm
+13144491240
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 7 am–6 pm
+13142828016
Visit websiteNear the end, short detour
Kirkwood, Missouri
Hours: 8 am–3 pm
+13146982200
Visit websiteNear the end, ~9 min detour
St. Louis, Missouri
Hours: 6 am–4 pm
+13149258588
Visit websiteNear the end, ~10 min detour
St. Louis, Missouri
Hours: 7 am–5 pm
+13142820332
Visit websiteLater in the drive, right off the route
Wentzville, Missouri
Hours: Open 24 hours
+18774943833
Visit websiteLater in the drive, short detour
Warrenton, Missouri
Hours: Open 24 hours
+18334662474
Visit websiteLater in the drive, short detour
Warrenton, Missouri
Hours: Open 24 hours
+18887584389
Visit websiteNear the end, short detour
O'Fallon, Missouri
+18554382474
Visit websiteNear the end, short detour
St Charles, Missouri
Hours: Open 24 hours
Early in the drive, ~9 min detour
Jefferson City, Missouri
Hours: Open 24 hours
+18777983752
Visit websiteAround the midpoint, right off the route
Fulton, Missouri
Hours: Open 24 hours
+18887584389
Visit websiteNear the end, short detour
Weldon Spring, Missouri
Hours: Open 24 hours
Visit websiteNear the end, right off the route
St. Louis, Missouri
Hours: 10 am–10 pm
+13149233960
Visit websiteNear the end, short detour
St. Louis, Missouri
Hours: 4 pm–1 am
+13147725994
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 59 and 192.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the ramp toward US 54 East: Fulton
Navigation decision point
Take the exit toward I 70 East, US 40 East: Saint Louis
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Take the exit onto US 40 toward I 64 East, US 40 East, US 61 South: Chesterfield
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Merge onto I 64; US 40; US 61 / Avenue of the Saints
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward 14th Street
Exit ramp - move to the correct lane early. Lane positioning matters here
Regular Gas
$30.22 one way
$60.44 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $33.18 | $66.36 |
| premium | $4.89 | $37.20 | $74.40 |
| diesel | $5.61 | $42.68 | $85.36 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$30
Meals
$25–$50
Total
$55–$80
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 67.6 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $20 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 58 | 0 | $20.30 | $9.28 |
| Efficient EV | 48.3 | 0 | $16.91 | $7.73 |
| EV Truck/SUV | 77.3 | 0 | $27.06 | $12.37 |
Gas CO2
68 kg
EV CO2
23 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Cole Camp on Tuesday
Local time
5:07 AM
CDT
Current temp
66°F
Unavailable
Destination
Late night in St. Louis on Tuesday
Local time
5:07 AM
CDT
Current temp
70°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Expect a turn-heavy local drive for this 193.9-mile stretch. With a 0% highway share, you'll be navigating primarily on surface streets and US highways, offering a more intimate connection with the landscape. The absence of long, uninterrupted stretches means you'll be engaging with the road frequently, making it a dynamic driving experience. This type of route often involves passing through towns and varied terrains, so keep your attention sharp for changes in speed limits and road conditions as you make your way toward St. Louis.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 59 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 193.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 59 miles: Navigation decision point; at 91 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 153.1 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. The city's planners have created an aesthetically beautiful city, with plenty of green space amidst buildings both old and new, framed by the majestic Mississippi and Missouri rivers. And capping it all is the world's tallest man-made monument, the beautiful and iconic Gateway Arch. St. Louis is a city of culture and surprisingly inexpensive. Among American cities, only Washington, D.C. has more free attractions for tourists and residents alike. Hotels, restaurants, and even parking garages avoid the premium pricing common in other big cities. Although often overlooked, St. Louis can be an affordable, educational, and fun family getaway.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 3h 58m. Total distance: 193.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 58m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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