Connecting Clarksville to Fishers, this 124.3-mile journey across Indiana serves as an efficient link between the southern and central parts of the state. You can expect to spend about 2 hours and 21 minutes behind the wheel, making this a perfect candidate for a single-day trip. With a fuel budget of approximately $19, the drive is both affordable and straightforward. Because the route stays within the Midwest, the transition from the Ohio River area toward the Indianapolis metro region is seamless. Since the entire trip is easily manageable in one go, you won't need to worry about booking an overnight stay unless your schedule requires a slower pace. It is a practical, no-nonsense path that prioritizes getting you to your destination quickly.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
62.1 miles from Clarksville, IN
A natural place for your longest stop of the day
, about 1h 7m into the drive
.
Main Roads
Road
Distance
Duration
I 65
100.2 mi
1h 48m
I 69
18.3 mi
22m
South Emerson Avenue
2.5 mi
4m
IN-37
0.8 mi
<1m
East 116th Street
0.4 mi
1m
Eastern Boulevard
0.2 mi
<1m
US 31
0.2 mi
<1m
East Southport Road
0.2 mi
<1m
Longest stretch:
I 65
— 100.2 mi, about 1h 48m
Turn-by-Turn Driving Directions
Step-by-step road directions between Clarksville, IN and Fishers, IN.
1
Start on East Brooks Avenue
32 ft·4 sec·East Brooks Avenue
2
Turn right onto Eastern Boulevard
0.2 mi·45 sec·Eastern Boulevard
3
Turn left onto US 31
0.2 mi·18 sec·US 31
Use the left lane.
4
Take the ramp
0.2 mi·27 sec
5
Merge onto I 65
100 mi·1 hr 48 min·I 65
6
Take the exit
0.4 mi·47 sec
Exit 103Toward Southport RoadUse the slight right lane.
7
Turn slight right
176 ft·4 sec
8
Turn straight onto East Southport Road
0.2 mi·26 sec·East Southport Road
9
Turn left onto South Emerson Avenue
2.5 mi·4 min·South Emerson Avenue
Use the left lane.
10
Take the ramp
0.5 mi·58 sec
11
Merge onto I 69; I 74; I 465
2.3 mi·2 min·I 69; I 74; I 465
12
Continue on I 69; I 465
12 mi·13 min·I 69; I 465
13
Keep slight right at fork onto I 69
4.2 mi·5 min·I 69
Exit 37Toward I 69 North: Fort Wayne
14
Keep slight right at fork onto SR 37
0.8 mi·49 sec·IN-37
Exit 205Toward SR 37 North: 116th StreetUse the slight right lane.
15
Take the exit
0.4 mi·56 sec
Exit 205Toward 116th StreetUse the straight / slight right lanes.
16
Turn left onto East 116th Street
0.4 mi·1 min·East 116th Street
Use the left lane.
17
Turn left onto Lantern Road
478 ft·16 sec·Lantern Road
18
Arrive at destination
Lantern Road
Trip Plan
Because this is a relatively short drive, you have plenty of flexibility regarding your departure time, though avoiding peak traffic hours near Indianapolis is always a wise move. You won't strictly need to plan for formal stops given the 2-hour and 21-minute duration, but keeping your fuel levels monitored ensures you stay within your $19 budget without needing to hunt for stations in high-price areas. Since the longest stretch is over 100 miles on I-65, make sure your vehicle is prepared for sustained highway speeds before you leave Clarksville. Use the freedom of this quick trip to your advantage by planning your arrival to align perfectly with your schedule in Fishers. If you feel fatigue setting in, remember that the transition to I-69 is the ideal moment to pull over and stretch your legs.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 62.1 miles from Clarksville, IN, or about 1h 7m into the drive.
The longest continuous stretch on this route runs about 100.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 27 miles or 30m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 62.1 miles or 1h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 51m
Traffic, exits, and arrival timing usually matter more near Fishers, IN than in the middle of the route.
Before You Leave
+
Open the route before leaving Clarksville, IN so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Clarksville, IN
This is one driving day of about 124.3 miles and 2h 21m.
Your first comfortable stop window is around 27 miles from Clarksville, IN.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on I 65 for about 100.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 12
5 decision points cluster between mile 0.2 and 123.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
0.2 mi into trip|~0m in|US 31
Turn left onto US 31
Lane positioning matters here
Use the left lane.
7
100.9 mi into trip|~1h 49m in
Take the exit toward Southport Road
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 103
Toward Southport Road
6
101.4 mi into trip|~1h 51m in|South Emerson Avenue
Turn left onto South Emerson Avenue
Lane positioning matters here
Use the left lane.
8
122.7 mi into trip|~2h 18m in|SR 37 / IN-37
Keep slight right at fork onto SR 37 / IN-37 toward SR 37 North: 116th Street
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Exit 205
Toward SR 37 North: 116th Street
7
123.4 mi into trip|~2h 19m in
Take the exit toward 116th Street
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 205
Toward 116th Street
Fuel & Cost
Regular Gas
$19.43 one way
$38.87 round trip
$3.97/gal25.4 MPG avg44 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$21.34
$42.67
premium
$4.89
$23.92
$47.84
diesel
$5.61
$27.44
$54.89
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$19
Meals
$25–$50
Total
$44–$69
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 43.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $13 in charging
· 0 stops
· 65% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
37.3
0
$13.05
$5.97
Efficient EV
31.1
0
$10.88
$4.97
EV Truck/SUV
49.7
0
$17.40
$7.96
Gas CO2
43 kg
EV CO2
15 kg (65% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Clarksville, IN
Morning
in Clarksville on Sunday
Local time
6:19 AM
EDT
Current temp
71°F
Unavailable
Live forecast
Destination
Fishers, IN
Morning
in Fishers on Sunday
Local time
6:19 AM
EDT
Current temp
54°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
17 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 21m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
Expect a focused highway experience, as 96% of your time will be spent on major interstates. You will spend the vast majority of your journey, specifically 100.2 miles, cruising along I-65 before navigating transitions onto I-69 and South Emerson Avenue. The personality of this drive is defined by high-speed, efficient transit rather than winding backroads. While you will encounter a steady pace, the final segments require a bit more attention as you shift from the long stretches of I-65 into the busier traffic patterns near Fishers. It is a predictable, interstate-heavy route that allows you to cover significant ground without the need for complex navigation.
96% highway — fuel and pacing are the main things to plan.
18 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 100.2 mi on I 65.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on I 65 and I 69. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.2 miles in near US 31.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 12 significant decision points across 124.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.2 miles (US 31): Lane positioning matters here; at 100.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 101.4 miles (South Emerson Avenue): Lane positioning matters here.
Elevation Profile
Mostly flat terrain
869 ft455 ft
Total Climb
502 ft
Total Descent
141 ft
Highest Point
869 ft
~113.9 mi in
Elevation Range
414 ft
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 21m. Total distance: 124.3 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 21m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (96%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 100.2 miles on I 65. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Fishers, IN before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.2 miles (US 31): Lane positioning matters here; at 100.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 101.4 miles (South Emerson Avenue): Lane positioning matters here.
Yes. A round trip is manageable in a single day if you plan a break at Fishers, IN before heading back.
