City of Greenville, MS to West Hattiesburg, MS is 208.2 miles and takes about 4h 19m via Highway 49 South, with a fuel budget near $33 and enough daylight to finish in a day. This trip stays within Mississippi, moving from the Southeast region to the Southeast region. It's a single-day trip that's mostly highway driving but transitions to surface roads. Expect a straightforward drive that's ideal for a quick transit between these two points.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
104.1 miles from City of Greenville, MS
A natural place for your longest stop of the day
, about 2h 10m into the drive
.
Main Roads
Road
Distance
Duration
Highway 49 South
80.3 mi
1h 37m
North Martin Luther King Drive
46.2 mi
55m
Jerry Clower Boulevard
38.8 mi
47m
US 82
15.8 mi
19m
US 49
11.5 mi
15m
MS 182
8.3 mi
12m
Lance Corporal Roy M Wheat Memorial Highway
1.9 mi
1m
I 20
1.2 mi
1m
Longest stretch:
Highway 49 South
— 80.3 mi, about 1h 37m
Traffic on I-20
Hour-of-day weekday pattern from 14 FHWA count stations on your route.
Peak
7 AM
~2,710 veh/hr typical
· worst 4,827
Quietest
2 AM
~220 veh/hr
Peak-to-quiet ratio
12.3×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 51 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between City of Greenville, MS and West Hattiesburg, MS.
1
Start on Sandy Avenue
46 ft·3 sec·Sandy Avenue
2
Turn right onto East Reed Road
0.7 mi·1 min·East Reed Road
3
Turn left onto MS 1
1.0 mi·1 min·Martin Luther King Junior Boulevard
4
Continue on MS 182
8.3 mi·12 min·MS 182
5
Turn left onto US 82; US 278
16 mi·19 min·US 82; US 278
Use the straight lane.
6
Turn right onto US 49W
46 mi·55 min·North Martin Luther King Drive
7
Keep slight right at fork onto US 49W
0.5 mi·53 sec·US 49W
Toward US 49 South: Jackson
8
Merge onto US 49
39 mi·47 min·Jerry Clower Boulevard
9
Take the exit onto US 49
4.9 mi·5 min·US 49
10
Keep slight left at fork onto US 49
3.8 mi·5 min·US 49
11
Merge onto I 20; I 55; US 49
1.1 mi·1 min·I 20; I 55; US 49
12
Keep slight right at fork onto I 20; US 49
347 ft·4 sec·I 20; US 49
Toward Meridian, Hattiesburg
13
Take the exit onto US 49
0.6 mi·42 sec·US 49
Toward Hattiesburg
14
Keep slight right at fork onto US 49
0.7 mi·1 min·US 49
Toward Richland, Hattiesburg
15
Merge onto US 49
80 mi·1 hr 37 min·Highway 49 South
Use the straight lane.
16
Continue on US 49; MS 42
0.4 mi·35 sec·US 49; MS 42
Use the straight lane.
17
Continue on US 49; MS 42
1.1 mi·1 min·US 49; MS 42
Use the straight lane.
18
Take the exit
0.4 mi·36 sec
Toward I 59 South: New Orleans, Gulf CoastUse the slight right lane.
19
Merge onto I 59
1.9 mi·1 min·Lance Corporal Roy M Wheat Memorial Highway
Toward Mississippi Gulf Coast
20
Take the exit
0.2 mi·21 sec
Toward US 98 West: Columbia, Hardy StreetUse the slight right lane.
21
Keep slight left at fork
236 ft·8 sec
Toward US 98 West: Hardy Street, University of Southern Mississippi, Columbia
22
Turn right onto US 98
1.2 mi·2 min·Hardy Street
Toward US 98 West: ColumbiaUse the straight / right lanes.
23
Turn left onto Weathersby Road
0.2 mi·35 sec·Weathersby Road
Use the left lane.
24
Turn right onto North Lane
0.1 mi·23 sec·North Lane
25
Arrive at destination
McKenzie Circle
Trip Plan
For this 4h 19m drive, leaving in the morning is recommended to maximize daylight. With only one recommended stop, you have flexibility in pacing. Keep an eye on your fuel gauge, as the longest stretch without a major town is about 80 miles. The estimated fuel cost is $33, so plan accordingly. Since this is a single-day trip, you can depart at your leisure, but an early start ensures a relaxed arrival.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 104.1 miles from City of Greenville, MS, or about 2h 10m into the drive.
The longest continuous stretch on this route runs about 80.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 46 miles or 59m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 104.1 miles or 2h 10m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 32m
Traffic, exits, and arrival timing usually matter more near West Hattiesburg, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving City of Greenville, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from City of Greenville, MS
This is one driving day of about 208.2 miles and 4h 19m.
Your first comfortable stop window is around 46 miles from City of Greenville, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Highway 49 South for about 80.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 18
5 decision points cluster between mile 121.1 and 206.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
121.1 mi into trip|~2h 31m in|I 20; US 49
Keep slight right at fork onto I 20; US 49 toward Meridian, Hattiesburg
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Meridian, Hattiesburg
6
121.8 mi into trip|~2h 32m in|US 49
Keep slight right at fork onto US 49 toward Richland, Hattiesburg
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Richland, Hattiesburg
7
204.3 mi into trip|~4h 13m in
Take the exit toward I 59 South: New Orleans, Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward I 59 South: New Orleans, Gulf Coast
7
206.5 mi into trip|~4h 16m in
Take the exit toward US 98 West: Columbia, Hardy Street
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward US 98 West: Columbia, Hardy Street
7
206.7 mi into trip|~4h 16m in
Keep slight left at fork toward US 98 West: Hardy Street, University of Southern Mississippi, Columbia
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 98 West: Hardy Street, University of...
Fuel & Cost
Regular Gas
$28.90 one way
$57.80 round trip
$3.53/gal25.4 MPG avg73 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$3.95
$32.34
$64.67
premium
$4.29
$35.16
$70.31
diesel
$4.80
$39.31
$78.62
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$29
Meals
$25–$50
Total
$54–$79
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 72.8 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $22 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
62.5
0
$21.86
$9.99
Efficient EV
52.1
0
$18.22
$8.33
EV Truck/SUV
83.3
1
$29.15
$13.32
Gas CO2
73 kg
EV CO2
24 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 19, 2026
Origin
City of Greenville, MS
Morning
in City of Greenville on Sunday
Local time
6:05 AM
CDT
Current temp
76°F
Mostly Clear
WSW 0 to 5 mph3% chanceLive forecast
Heat Advisory
Heat Advisory issued July 18 at 1:23PM CDT until July 19 at 7:00PM CDT by NWS Mobile AL
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 18 at 8:00PM CDT by NWS Memphis TN
Destination
West Hattiesburg, MS
Morning
in West Hattiesburg on Sunday
Local time
6:05 AM
CDT
Current temp
75°F
Mostly Clear
WNW 0 to 5 mph4% chanceLive forecast
Heat Advisory
Heat Advisory issued July 18 at 1:23PM CDT until July 19 at 7:00PM CDT by NWS Mobile AL
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 18 at 8:00PM CDT by NWS Memphis TN
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 19m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
3 mi from route
~7 min detour
Free
near mile 114.9
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route is 56% highway, with the majority of your time spent on Highway 49 South. You'll encounter the longest continuous stretch of highway at 80.3 miles on Highway 49 South. The drive transitions from highway cruising to surface roads, indicated by a shift in driving conditions. Be prepared for a change in road type as you approach your destination.
56% highway, the rest on surface roads — varied driving throughout.
25 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 80.3 mi on Highway 49 South.
How Hard Is This Drive?
10/10
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 121.1 miles in near I 20; US 49.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 208.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 121.1 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 121.8 miles (US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 204.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
384 ft107 ft
Total Climb
297 ft
Total Descent
167 ft
Highest Point
384 ft
~163.6 mi in
Elevation Range
277 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between City of Greenville, MS and West Hattiesburg, MS, road signs point toward Meridian, Hattiesburg and Richland.
Meridian
121.1 mi in|~2h 31m|via I 20; US 49
Hattiesburg
121.1 mi in|~2h 31m|via I 20; US 49
Richland
121.8 mi in|~2h 32m|via US 49
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 4h 19m. Total distance: 208.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 19m drive, comfortable solo distance.
Scenic Drive
Mixed highway & surface route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 80.3 miles on Highway 49 South. The full list of main roads is in the Roads section above.
Yes — we found about 9 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at West Hattiesburg, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 9 rest areas along the route for bathroom stops.
The main spots that need attention: at 121.1 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 121.8 miles (US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 204.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Medgar and Myrlie Evers Home National Monument. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.3 hours each way, an in-and-out day trip would put you behind the wheel for 8.7 hours — manageable with a long break at West Hattiesburg, MS, but most travelers stay overnight.
