Cajun Crab House Seafood Restaurant
Near the end, short detour
Columbia, Missouri
Hours: 3–8 pm
+15732346277
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Oct 21, 2026 · Editorial standards
Drive Time
5h 4m
Distance
265.2 mi
427 km
Drive Score
10/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$44
one way
EV Charging
Good
8 stations
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Charleston, MO
Wikimedia Commons
Columbia, MO
Chris Duan
Charleston, MO to Columbia, MO is 265.2 miles and takes about 5h 4m via I 55, with a fuel budget near $41 and enough daylight to finish in a day. This trip stays within Missouri, moving from the Midwest region to another part of the Midwest. The route is primarily highway driving, offering a straightforward path with a good portion on the Dwight D Eisenhower Highway and Avenue of the Saints. Consider this drive if you're looking for a direct, one-day trip across the state with minimal navigation challenges.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
132.6 miles from Charleston, MO
A natural place for your longest stop of the day , about 2h 24m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 55 | 128.6 mi | 2h 18m |
| Dwight D Eisenhower Highway | 80.7 mi | 1h 35m |
| Avenue of the Saints | 25.4 mi | 30m |
| I 270 | 11.5 mi | 14m |
| I 57 | 10 mi | 10m |
| Sheriff Roger I. Wilson Memorial Highway | 2 mi | 2m |
| Rosa Parks Highway | 1.3 mi | 1m |
| North Providence Road | 1.2 mi | 2m |
Hour-of-day weekday pattern from 20 FHWA count stations on your route.
Peak
3 PM
~2,319 veh/hr typical · worst 2,912
Quietest
1 AM
~234 veh/hr
Peak-to-quiet ratio
9.9×
busier at peak than in the quiet hours
Averaged across 105 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Step-by-step road directions between Charleston, MO and Columbia, MO.
Start on US 62; MO 77
Turn right onto I 57 Business; MO 105
Take the ramp onto I 57 Business
Merge onto I 57; US 60
Take the exit
Merge onto I 55
Keep slight left at fork onto I 55
Continue on I 55
Take the exit
Keep slight left at fork
Continue on this road
Merge onto I 270
Take the exit
Keep slight left at fork
Continue on this road
Merge onto I 64; US 40; US 61
Take the exit onto US 40
Merge onto I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Take the exit
Turn left onto MO 163
Arrive at destination
Given the 5h 4m estimated drive time, starting your trip in Charleston, MO after breakfast will allow you to reach Columbia, MO with plenty of daylight to spare. With only one recommended stop, you have flexibility in pacing. The fuel cost is estimated at $41, so be sure to factor that into your budget. Keep an eye on your fuel gauge, especially during the 128.6-mile stretch on I 55, as services can be spread out on interstates.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 58 miles or 1h 3m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 132.6 miles or 2h 24m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 6m
Traffic, exits, and arrival timing usually matter more near Columbia, MO than in the middle of the route.
Open the route before leaving Charleston, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Charleston, MO
This is one driving day of about 265.2 miles and 5h 4m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
133 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 58 miles helps settle the day before fatigue starts building.
The midpoint is around 132.6 miles from Charleston, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 55 if your tank is already low. That segment runs about 128.6 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Best meal stop · home stretch
Columbia, Missouri
Near the end, short detour
Hours: 3–8 pm
+15732346277
Best coffee break · home stretch
Columbia, Missouri
Near the end, right off the route
Hours: 5–8 pm
+17024270048
Cafe Berlin
Columbia, Missouri
Vybe Coffeehouse & Cafe
Charleston, Missouri
Near the end, short detour
Columbia, Missouri
Hours: 3–8 pm
+15732346277
Visit websiteNear the start, ~9 min detour
Cape Girardeau, Missouri
Hours: 11 am–9:30 pm
+15733353090
Visit websiteNear the start, ~9 min detour
Cape Girardeau, Missouri
Hours: Open 24 hours
+15738033138
Visit websiteNear the end, right off the route
Columbia, Missouri
Hours: 5–8 pm
+17024270048
Visit websiteNear the end, right off the route
Columbia, Missouri
Hours: 8 am–2 pm
+15734410400
Visit websiteNear the start, right off the route
Charleston, Missouri
Hours: 6 am–2 pm
+15732338099
Around the midpoint, short detour
Kirkwood, Missouri
Hours: 8 am–3 pm
+13146982200
Visit websiteAround the midpoint, ~10 min detour
Ste. Genevieve, Missouri
Hours: 10:30 am–8 pm
+15738833562
Around the midpoint, right off the route
O'Fallon, Missouri
+18554382474
Visit websiteNear the end, short detour
Columbia, Missouri
Hours: Open 24 hours
+18889982546
Visit websiteNear the end, short detour
Columbia, Missouri
Hours: Open 24 hours
+18337484267
Visit websiteNear the end, short detour
Columbia, Missouri
Hours: Open 24 hours
+18887584389
Visit websiteNear the end, short detour
Columbia, Missouri
Hours: Open 24 hours
Visit websiteNear the end, short detour
Columbia, Missouri
Hours: Open 24 hours
Visit websiteNear the end, short detour
Columbia, Missouri
Hours: Open 24 hours
+18889982546
Visit websiteNear the end, short detour
Columbia, Missouri
Hours: Open 24 hours
+18887584389
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 141.6 and 180.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the exit toward I 270 West, I 255 East: Kansas City, Chicago
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward I 270 West: Kansas City
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward I 64, US 40, US 61: Wentzville, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward I 64 West, US 40 West, US 61 North: Wentzville
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Regular Gas
$44.24 one way
$88.48 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.62 | $48.27 | $96.54 |
| premium | $5.25 | $54.85 | $109.69 |
| diesel | $6.18 | $64.51 | $129.03 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$44
Meals
$25–$50
Total
$69–$94
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 92.8 kg one way. Prices: EIA weekly data, 2026-10-19.
Driving Electric?
About $28 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 79.6 | 0 | $27.85 | $12.73 |
| Efficient EV | 66.3 | 0 | $23.21 | $10.61 |
| EV Truck/SUV | 106.1 | 1 | $37.13 | $16.97 |
Gas CO2
93 kg
EV CO2
31 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Night in Charleston on Tuesday
Local time
10:28 PM
CDT
Current temp
75°F
Sunny
Destination
Night in Columbia on Tuesday
Local time
10:28 PM
CDT
Current temp
71°F
Mostly Sunny
68°F
Chesterfield, MO
133 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Historical Park
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Park data from the National Park Service API. Alerts update every 2 hours.
You'll spend about 57% of this 265.2-mile drive on highways. The longest continuous stretch on a major highway is 128.6 miles on I 55. After this extensive highway segment, the route transitions to surface roads for the remainder of the trip. Expect a mix of high-speed cruising and potentially more local traffic as you approach your destination.
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 141.6 miles in.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 265.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 141.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 141.8 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 154.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Mostly flat terrain
Total Climb
907 ft
Total Descent
521 ft
Highest Point
899 ft
~208.5 mi in
Elevation Range
578 ft
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Charleston, MO and Columbia, MO, road signs point toward Chicago and Saint Louis.
Chicago
Saint Louis
Founded 1837
Founded 1821
Columbia is a bustling college town in Missouri, halfway between St. Louis and Kansas City. It is home of the University of Missouri (also known as 'Mizzou') as well as two other post-secondary institutions Stephens College and Columbia College.
Top landmarks
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 5h 4m. Total distance: 265.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 4m drive, comfortable solo distance.
Scenic Drive
Mixed highway & surface route profile with national parks nearby.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NPS for national parks, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.
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