Campbell to Columbia is 266.7 miles and takes about 5h 51m via US 63, US 60, and MO 19, with a fuel budget near $42 and enough daylight to finish in a day. This Midwest drive stays within Missouri, transitioning from the southern part of the state to the central region. Given its 91% highway share and a recommended single day of travel, expect a fairly direct journey focused on covering ground efficiently. It's a straightforward trip for those prioritizing arrival over extensive sightseeing along the way.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
133.4 miles from Campbell, MO
A natural place for your longest stop of the day
, about 2h 57m into the drive
.
Main Roads
Road
Distance
Duration
US 63
74.9 mi
1h 31m
US 60
60 mi
1h 11m
MO 19
54.4 mi
1h 15m
MO 53
26.5 mi
39m
MO 72
24.3 mi
31m
North Bishop Avenue
12.9 mi
15m
South Westwood Boulevard
2.4 mi
3m
East Stadium Boulevard
2.3 mi
3m
Longest stretch:
US 63
— 74.9 mi, about 1h 31m
Turn-by-Turn Driving Directions
Step-by-step road directions between Campbell, MO and Columbia, MO.
1
Start on US 62
0.2 mi·14 sec·Grand Avenue
2
Turn right onto MO OO
0.6 mi·1 min·Frisco Street
3
At end of road, turn left onto MO 53
26 mi·39 min·MO 53
4
Turn right onto US 67 Business
2.4 mi·3 min·South Westwood Boulevard
5
Continue on US 60 Business; US 67 Business
0.3 mi·25 sec·State Street
6
Continue on US 60 Business; US 67 Business
1.6 mi·2 min·North Westwood Boulevard
7
Continue on US 67; US 60 Business
0.4 mi·37 sec·US 67; US 60 Business
8
Continue on US 60; US 67
4.0 mi·4 min·US 60; US 67
9
Take the exit onto US 60
56 mi·1 hr 6 min·US 60
10
Turn right onto MO 19
13 mi·18 min·MO 19
11
Turn slight right onto MO 19
42 mi·56 min·MO 19
12
Turn left onto MO 32; MO 72
1.5 mi·2 min·MO 32; MO 72
13
Turn right onto MO 72
24 mi·31 min·MO 72
14
Turn right onto Salem Avenue
0.7 mi·1 min·Salem Avenue
15
Turn right onto Holloway Street
0.9 mi·2 min·Holloway Street
Use the straight / right lanes.
16
At end of road, turn left onto East 18th Street
0.2 mi·36 sec·East 18th Street
17
Continue on North Walnut Street
0.1 mi·29 sec·North Walnut Street
18
Turn right onto I 44 Business; US Historic 66; US 63
13 mi·15 min·North Bishop Avenue
Use the right lane.
19
Continue on US 63; MO 28
48 mi·1 hr 2 min·US 63; MO 28
20
Take the exit onto US 63
0.3 mi·40 sec·US 63
Toward US 54 East, US 63 North: Fulton, Columbia
21
Merge onto US 54; US 63
1.4 mi·1 min·US 54; US 63
22
Take the exit onto US 63
26 mi·28 min·US 63
Toward US 63 North: Columbia
23
Take the exit
0.2 mi·33 sec
Toward MO 740
24
Turn left onto MO 740
2.3 mi·3 min·East Stadium Boulevard
25
Turn right onto MO 163
1.0 mi·2 min·South Providence Road
26
Arrive at destination
MO 163
Trip Plan
Consider an early morning departure from Campbell to maximize daylight and take advantage of the single-day travel recommendation. With a drive time under 6 hours, you can comfortably complete this trip in one go, but plan for one well-timed stop to stretch your legs. Keep an eye on your fuel gauge, especially during the longest stretch of 74.9 miles on US 63, as services might be less frequent in certain sections. The $42 fuel cost estimate is helpful for budgeting your trip.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 133.4 miles from Campbell, MO, or about 2h 57m into the drive.
The longest continuous stretch on this route runs about 74.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 59 miles or 1h 20m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 133.4 miles or 2h 57m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 52m
Traffic, exits, and arrival timing usually matter more near Columbia, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Campbell, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Campbell, MO
This is one driving day of about 266.7 miles and 5h 51m.
Your first comfortable stop window is around 59 miles from Campbell, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 63 for about 74.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 14
5 decision points cluster between mile 0.7 and 235.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0.7 mi into trip|~1m in|MO 53
At end of road, turn left onto MO 53
Navigation decision point
4
91.8 mi into trip|~1h 58m in|MO 19
Turn right onto MO 19
Navigation decision point
5
172.8 mi into trip|~3h 51m in|Holloway Street
Turn right onto Holloway Street
Lane positioning matters here
Use the straight / right lanes.
6
174 mi into trip|~3h 55m in|I 44 Business; US Historic 66; US 63 / North Bishop Avenue
Turn right onto I 44 Business; US Historic 66; US 63 / North Bishop Avenue
Lane positioning matters here
Use the right lane.
5
235.4 mi into trip|~5h 13m in|US 63
Take the exit onto US 63 toward US 54 East, US 63 North: Fulton, Columbia
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 54 East, US 63 North: Fulton, Columbi...
Fuel & Cost
Regular Gas
$41.70 one way
$83.39 round trip
$3.97/gal25.4 MPG avg93 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$45.78
$91.56
premium
$4.89
$51.32
$102.65
diesel
$5.61
$58.88
$117.77
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$42
Meals
$25–$50
Total
$67–$92
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 93.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $28 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
80
0
$28.00
$12.80
Efficient EV
66.7
0
$23.34
$10.67
EV Truck/SUV
106.7
1
$37.34
$17.07
Gas CO2
93 kg
EV CO2
31 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Campbell, MO
Night
in Campbell on Saturday
Local time
9:45 PM
CDT
Current temp
75°F
Unavailable
Live forecast
Destination
Columbia, MO
Night
in Columbia on Saturday
Local time
9:45 PM
CDT
Current temp
74°F
Unavailable
Live forecast
54°F
Houston, MO
133 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 51m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This is a highway-focused drive with 91% of the route utilizing major roads. You'll encounter stretches that are primarily two-lane highways, making for a more continuous driving experience. The longest uninterrupted segment spans 74.9 miles, likely on US 63, meaning you can settle in for a good amount of time without frequent turns or significant slowdowns. The roads themselves are designed for efficient travel, so anticipate a steady pace for most of your journey.
91% highway — fuel and pacing are the main things to plan.
26 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 74.9 mi on US 63.
How Hard Is This Drive?
3/10
This is a straightforward highway drive that stays mostly on US 63 and US 60. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.7 miles in near MO 53.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 5h 51m drive. You will face about 14 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 0.7 miles (MO 53): Navigation decision point; at 91.8 miles (MO 19): Navigation decision point; at 172.8 miles (Holloway Street): Lane positioning matters here.
Columbia is a bustling college town in Missouri, halfway between St. Louis and Kansas City. It is home of the University of Missouri (also known as 'Mizzou') as well as two other post-secondary institutions Stephens College and Columbia College.
The longest stretch is about 74.9 miles on US 63. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.7 miles (MO 53): Navigation decision point; at 91.8 miles (MO 19): Navigation decision point; at 172.8 miles (Holloway Street): Lane positioning matters here.
Not recommended in a single day. At 5.9 hours each way, a round trip means 11.7 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Columbia, MO before the return drive.
