If you are planning to travel from Brandon to Oxford, Mississippi, you are looking at a straightforward 108.9-mile journey through the Southeast. Expect to spend about 2 hours and 23 minutes behind the wheel, making this an ideal candidate for a single-day excursion. With a modest fuel budget of approximately $17, the trip is both economical and efficient for those looking to reach their destination without an overnight stay. Since both cities are located within Mississippi, you will experience a consistent regional feel as you transition from the central part of the state toward the northern hills. Whether you are heading out for a quick weekend getaway or a necessary visit, this route offers a reliable connection between these two Mississippi hubs.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
54.4 miles from Brandon, MS
A natural place for your longest stop of the day
, about 1h into the drive
.
Main Roads
Road
Distance
Duration
I 55
53.8 mi
57m
US 84
22.7 mi
26m
I-20
10.1 mi
11m
Gloster Road
6.5 mi
15m
Oxford-Meadville Road
6.3 mi
15m
Yap 3 Road
2.6 mi
6m
US 98
1.9 mi
2m
I 20
1.6 mi
2m
Longest stretch:
I 55
— 53.8 mi, about 57m
Turn-by-Turn Driving Directions
Step-by-step road directions between Brandon, MS and Oxford, MS.
1
Start on US 80
1.1 mi·1 min·East Government Street
Use the straight lane.
2
Take the ramp
0.5 mi·1 min
3
Merge onto I 20
10 mi·11 min·I-20
4
Merge onto I 20; I 55; US 49
1.6 mi·2 min·I 20; I 55; US 49
5
Keep slight left at fork onto I 55
54 mi·57 min·I 55
Toward I 55 South: McComb, New Orleans
6
Take the exit
0.3 mi·35 sec
Toward US 84: South Brookhaven, Natchez
7
Keep slight right at fork
409 ft·9 sec
Toward US 84: South Brookhaven, Natchez
8
Merge onto US 84
23 mi·26 min·US 84
9
Turn left onto MS 184
1.4 mi·2 min·MS 184
10
Turn left onto US 98
1.9 mi·2 min·US 98
11
Turn right onto Yap 3 Road
2.6 mi·6 min·Yap 3 Road
12
Continue on Gloster Road
3.8 mi·9 min·Gloster Road
13
At end of road, turn right onto Gloster Road
2.8 mi·6 min·Gloster Road
14
Continue on Oxford-Meadville Road
6.3 mi·15 min·Oxford-Meadville Road
15
Arrive at destination
Oxford-Meadville Road
Trip Plan
Because this is a relatively short trip, you have plenty of flexibility in your schedule, but aiming for an early departure can help you avoid potential traffic bottlenecks on the interstate. Since there are no mandatory stops listed, you can easily complete the 108.9-mile distance in one go, though keeping an eye on your fuel gauge is wise given the $17 estimated cost. If you find yourself needing a break, plan your stop before or after the 53.8-mile stretch on I-55 to ensure you aren't stuck in a construction zone or high-traffic area. Utilizing the interstate system for the vast majority of your travel means you should stay alert for merging traffic, especially during peak commute times. Always double-check your route map before leaving Brandon, as shifting traffic patterns on I-55 can occasionally impact your total travel time.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 54.4 miles from Brandon, MS, or about 1h into the drive.
The longest continuous stretch on this route runs about 53.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 24 miles or 27m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 54.4 miles or 1h in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 40m
Traffic, exits, and arrival timing usually matter more near Oxford, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Brandon, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Brandon, MS
This is one driving day of about 108.9 miles and 2h 23m.
Your first comfortable stop window is around 24 miles from Brandon, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on I 55 for about 53.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 11
5 decision points cluster between mile 13.3 and 91.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
13.3 mi into trip|~16m in|I 55
Keep slight left at fork onto I 55 toward I 55 South: McComb, New Orleans
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 55 South: McComb, New Orleans
5
67.1 mi into trip|~1h 13m in
Take the exit toward US 84: South Brookhaven, Natchez
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 84: South Brookhaven, Natchez
7
67.4 mi into trip|~1h 14m in
Keep slight right at fork toward US 84: South Brookhaven, Natchez
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 84: South Brookhaven, Natchez
4
90.2 mi into trip|~1h 41m in|MS 184
Turn left onto MS 184
Navigation decision point
4
91.6 mi into trip|~1h 43m in|US 98
Turn left onto US 98
Navigation decision point
Fuel & Cost
Regular Gas
$16.45 one way
$32.89 round trip
$3.84/gal25.4 MPG avg38 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$18.05
$36.11
premium
$4.56
$19.55
$39.09
diesel
$5.61
$24.04
$48.09
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$16
Meals
$25–$50
Total
$41–$66
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 38.1 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
32.7
0
$11.43
$5.23
Efficient EV
27.2
0
$9.53
$4.36
EV Truck/SUV
43.6
0
$15.25
$6.97
Gas CO2
38 kg
EV CO2
13 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Brandon, MS
Morning
in Brandon on Tuesday
Local time
7:43 AM
CDT
Current temp
84°F
Unavailable
Live forecast
Destination
Oxford, MS
Morning
in Oxford on Tuesday
Local time
7:43 AM
CDT
Current temp
83°F
Unavailable
Live forecast
84°F
Brookhaven, MS
54 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 23m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
5 mi from route
~13 min detour
Free
near mile 11.3
Discover the history of all the peoples of Natchez, Mississippi, from European settlement, African enslavement, the American cotton economy, to the Civil Rights struggle on the lower Mississippi River...
30 mi from route
~75 min detour
Free
near mile 101.4
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This drive is heavily highway-focused, with 84% of your travel taking place on major thoroughfares like I-55, US 84, and I-20. You will spend the bulk of your time focused on the road, including a significant 53.8-mile stretch on I-55 that serves as the longest uninterrupted portion of the trip. While the route prioritizes speed and efficiency, the transition between these major arteries keeps the experience from feeling entirely monotonous. Because the majority of the journey is spent on high-capacity roads, you can expect a steady, predictable pace for the duration of your 2-hour and 23-minute transit. It is a functional drive designed to get you from point A to point B with minimal complexity.
84% highway — fuel and pacing are the main things to plan.
15 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 53.8 mi on I 55.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on I 55 and US 84. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 13.3 miles in near I 55.
Driving Effort5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 108.9 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 13.3 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 67.1 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 67.4 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Brandon, MS and Oxford, MS, road signs point toward New Orleans and Natchez.
Oxford is a historic, picturesque town in North Central Mississippi. With its scenic town square, acclaimed restaurants, unique boutiques, oak-shaded neighborhoods, and friendly people, Oxford is the model Southern town. Named after Oxford, England, in hopes of attracting a university, the town was selected as the home of the University of Mississippi in 1848, which dominates life here today.
Doable as a same-day drive at 2h 23m. Total distance: 108.9 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 23m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (84%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 53.8 miles on I 55. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 13.3 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 67.1 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 67.4 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Yes — Medgar and Myrlie Evers Home National Monument and Natchez National Historical Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Oxford, MS before heading back.
