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Trip from Wilkes-Barre, PA to Pittsburgh, PA

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Jul 20, 2026 · Editorial standards

Drive Time

5h 26m

Distance

265.1 mi

427 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$42

one way

EV Charging

Good

8 stations

Best Time to Leave

Save up to 40 min
4 AM
5h 13m ★
6 AM
5h 26m
8 AM
5h 53m
10 AM
5h 36m
12 PM
5h 33m
3 PM
5h 37m
5 PM
5h 52m
8 PM
5h 18m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

county seat of Luzerne County, Pennsylvania, United States

Wilkes-Barre, PA

Wikimedia Commons

city and county seat in Allegheny County, Pennsylvania, United States

Pittsburgh, PA

Wikimedia Commons

Trip Overview

Wilkes-Barre to Pittsburgh is 265.1 miles and takes about 5h 26m via Keystone Shortway, William Penn Highway, and I-99, with a fuel budget near $43 and enough daylight to finish in a day. This trip stays within Pennsylvania, moving from the Northeast region to the same region. The drive is predominantly on surface roads, offering a more local feel compared to interstate-only travel. With a single recommended stop and a relatively short duration, this route is well-suited for a single-day excursion.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

132.6 miles from Wilkes-Barre, PA

A natural place for your longest stop of the day , about 2h 31m into the drive .

Main Roads

Road Distance Duration
Keystone Shortway 98.5 mi 1h 47m
William Penn Highway 61.2 mi 1h 25m
I 99 33.8 mi 36m
Jacksonville Road 24.2 mi 28m
I 81 14.4 mi 16m
Penn-Lincoln Parkway East 13.5 mi 18m
Admiral Peary Highway 13.4 mi 19m
Hazle Street 1 mi 2m
Longest stretch: Keystone Shortway — 98.5 mi, about 1h 47m

Traffic on I-80

Hour-of-day weekday pattern from 36 FHWA count stations on your route.

Peak

3 PM

~1,145 veh/hr typical · worst 1,582

Quietest

2 AM

~189 veh/hr

Peak-to-quiet ratio

6.1×

busier at peak than in the quiet hours

12a 6a noon 6p 11p

Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).

Turn-by-Turn Driving Directions

Step-by-step road directions between Wilkes-Barre, PA and Pittsburgh, PA.

1

Start on Public Square

0.1 mi · 26 sec · Public Square
2

Continue on South Main Street

0.7 mi · 1 min · South Main Street
3

Turn left onto Hazle Street

1.0 mi · 2 min · Hazle Street
4

Turn left onto Blackman Street

0.6 mi · 1 min · Blackman Street
5

Turn right onto PA 309

0.2 mi · 29 sec · Wilkes-Barre Township Boulevard
6

Take the ramp

0.3 mi · 43 sec
7

Merge onto I 81

14 mi · 16 min · I 81
8

Take the exit

0.7 mi · 1 min
Exit 151B Toward I-80 West: Bloomsburg
9

Merge onto I 80

99 mi · 1 hr 47 min · Keystone Shortway
10

Take the exit

0.3 mi · 53 sec
Exit 161 Toward I 99 South, US 220 South, PA 26: Bellefonte
11

Turn left onto US 220; PA 26

24 mi · 28 min · Jacksonville Road
Use the straight lane.
12

Keep slight left at fork onto I 99; US 220

34 mi · 36 min · I 99; US 220
Toward I 99 South, US 220 South: Port Matilda, Altoona
13

Take the exit

0.8 mi · 1 min
Toward US 22: Ebensburg, Hollidaysburg
14

Continue on this road

0.5 mi · 43 sec · this road
15

Continue on US 22

16 mi · 19 min · William Penn Highway
16

Continue on US 22

13 mi · 19 min · Admiral Peary Highway
Use the straight lane.
17

Continue on US 22

45 mi · 1 hr 6 min · William Penn Highway
Use the straight / right lanes.
18

Keep slight right at fork onto I 376; US 22

13 mi · 18 min · Penn-Lincoln Parkway East
Toward I 376 West, US 22 West: Pittsburgh Use the slight left lane.
19

Take the exit

0.2 mi · 38 sec
Exit 71B Toward Second Avenue Use the straight / slight right lanes.
20

Turn straight onto Second Avenue

0.3 mi · 41 sec · Second Avenue
21

At end of road, turn right onto Ross Street

0.2 mi · 32 sec · Ross Street
22

Turn left onto Fifth Avenue

352 ft · 10 sec · Fifth Avenue
23

Turn right onto Grant Street

513 ft · 21 sec · Grant Street
Use the right lane.
24

Arrive at destination

Grant Street

Trip Plan

To make the most of this 5-hour, 265-mile drive, consider an early morning departure from Wilkes-Barre to maximize daylight. The route is designed for a single day, so you'll likely only need one planned stop for fuel or a quick break. Be mindful of the 98.5-mile stretch on the Keystone Shortway, as it's the longest continuous segment before you'll need to look for services. With a fuel cost estimated at $43, it's a budget-friendly option for a day trip across Pennsylvania.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 132.6 miles from Wilkes-Barre, PA, or about 2h 31m into the drive.
The longest continuous stretch on this route runs about 98.5 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 58 miles or 1h 8m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 132.6 miles or 2h 31m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 16m

Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.

Before You Leave

+

Open the route before leaving Wilkes-Barre, PA so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Wilkes-Barre, PA

This is one driving day of about 265.1 miles and 5h 26m.

Your first comfortable stop window is around 58 miles from Wilkes-Barre, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Keystone Shortway for about 98.5 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Altoona, PA, PA

Mid-route town

Meal stop

Altoona, PA

133 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Danville, PA

Fuel and coffee

A short stop after about 58 miles helps settle the day before fatigue starts building.

Central City, PA

Meal break

The midpoint is around 132.6 miles from Wilkes-Barre, PA, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Keystone Shortway if your tank is already low. That segment runs about 98.5 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Stops Along Your Drive

Picked by where they fit in your drive — first break, midpoint reset, final stretch.

Best meal stop · home stretch

Kiku Japanese Restaurant

4.5 ★ ★ ★ ★ ★

Pittsburgh, Pennsylvania

Near the end, right off the route

Home stretch · 0min to go 0.7 mi from route ~2 min detour $20 to $30

Hours: 12–2 pm

+14127653200

Visit website

Grand Concourse

4.2 ★ ★ ★ ★ ☆

Pittsburgh, Pennsylvania

0.7 mi

J & J's Family Restaurant & Catering

4.6 ★ ★ ★ ★ ★

Pittsburgh, Pennsylvania

1 mi

Kiku Japanese Restaurant

4.5 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.7 mi from route ~2 min detour $20 to $30

Pittsburgh, Pennsylvania

Hours: 12–2 pm

+14127653200

Visit website

Grand Concourse

4.2 ★ ★ ★ ★ ☆

Near the end, right off the route

Home stretch 0.7 mi from route ~2 min detour Expensive

Pittsburgh, Pennsylvania

Hours: 11:30 am–9:30 pm

+14122611717

Visit website

J & J's Family Restaurant & Catering

4.6 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 1 mi from route ~2 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 8 am–5 pm

+14123811822

Cambod-Ican Kitchen Restaurant

4.6 ★ ★ ★ ★ ★

Near the end, short detour

Home stretch 1.1 mi from route ~3 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 5:30 pm–2 am

+14123816199

Visit website

KAVSAR RESTAURANT

4.4 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 1 mi from route ~3 min detour Moderately

Pittsburgh, Pennsylvania

Hours: 4–9:30 pm

+14124888708

Visit website

La Tavola Italiana Restaurant

4.5 ★ ★ ★ ★ ★

Near the end, short detour

Home stretch 1.1 mi from route ~3 min detour $30 to $50

Pittsburgh, Pennsylvania

Hours: 5–9 pm

+14124813336

Visit website

Zarra's Restaurant

4.2 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 2.4 mi from route ~6 min detour Moderately

Pittsburgh, Pennsylvania

Hours: 5–9:30 pm

+14126828296

Visit website

Ginza Japanese Restaurant

4.5 ★ ★ ★ ★ ★

Near the end, short detour

Home stretch 2.9 mi from route ~7 min detour $20 to $30

Pittsburgh, Pennsylvania

Hours: 11 am–9:30 pm

+14126887272

Visit website

Orbis Caffe

4.6 ★ ★ ★ ★ ★

Near the end, ~12 min detour

Home stretch 4.8 mi from route ~12 min detour $1 to $10

Pittsburgh, PA

Hours: 7 am–9 pm

+14125631220

Visit website

Tesla Supercharger

3.8 ★ ★ ★ ★ ☆

Near the start, short detour

1.9 mi from route ~5 min detour

Wilkes-Barre Township, Pennsylvania

Hours: Open 24 hours

+18777983752

Visit website

EV Connect Charging Station

4.3 ★ ★ ★ ★ ☆

Near the start, short detour

1.9 mi from route ~5 min detour

Kingston, Pennsylvania

+18668167584

Visit website

ChargePoint Charging Station

5.0 ★ ★ ★ ★ ★

Near the start, short detour

First break 2.2 mi from route ~6 min detour

Nescopeck, Pennsylvania

Hours: Open 24 hours

+18887584389

Visit website

InCharge Charging Station

4.0 ★ ★ ★ ★ ☆

Near the start, short detour

1.8 mi from route ~4 min detour

Wilkes-Barre Township, Pennsylvania

Hours: Open 24 hours

+18333994638

Visit website

Tesla Supercharger

4.0 ★ ★ ★ ★ ☆

Near the start, short detour

First break 2.4 mi from route ~6 min detour

Drums, Pennsylvania

Hours: Open 24 hours

+18777983752

Visit website

Electrify America Charging Station

3.8 ★ ★ ★ ★ ☆

Near the start, short detour

First break 3.4 mi from route ~8 min detour

Bloomsburg, Pennsylvania

Hours: Open 24 hours

+18336322778

Visit website

Autel Charging Station

5.0 ★ ★ ★ ★ ★

Near the end, ~9 min detour

Home stretch 3.6 mi from route ~9 min detour

Pittsburgh, Pennsylvania

Hours: Open 24 hours

ChargePoint Charging Station

2.7 ★ ★ ★ ☆ ☆

Near the start, short detour

2.1 mi from route ~5 min detour

Wilkes-Barre Township, Pennsylvania

Hours: Open 24 hours

+18887584389

Visit website

Rest Area

0 mi from route

Montour County Rest Area Westbound

0 mi from route

Service Plaza

0 mi from route

Love's Travel Stop

0.1 mi from route

TA

0.1 mi from route

Pilot Travel Center

0.1 mi from route

Pilot Travel Center

0.1 mi from route

Clinton County Rest Area Eastbound

0.1 mi from route

Blue Ridge Travel Plaza

0.1 mi from route

Onvo Travel Plaza

0.1 mi from route

Flying J Travel Center

0.2 mi from route

Flying J Travel Center

0.2 mi from route

Luzerne County Rest Area Northbound

0.2 mi from route

Clinton County Rest Area Westbound

0.2 mi from route

Montour County Rest Area Eastbound

0.2 mi from route

Columbia County Rest Area Eastbound

0.2 mi from route

Columbia County Rest Area Westbound

0.2 mi from route

Onvo Travel Plaza

0.2 mi from route

TA

0.3 mi from route

Service Plaza

0.4 mi from route

TA

2.2 mi from route

Primanti Bros. Restaurant and Bar

4.3 ★ ★ ★ ★ ☆

Near the end, right off the route

Home stretch 0.4 mi from route ~1 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 10:30 am–12 pm

+14122611599

Visit website

Primanti Bros. Restaurant and Bar

4.5 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.9 mi from route ~2 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 8 am–12 pm

+14122632142

Visit website

Primanti Bros. Restaurant and Bar

4.2 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 1.2 mi from route ~3 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 11 am–1 pm

+14123812583

Visit website

Primanti Bros. Restaurant and Bar

4.3 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 2.1 mi from route ~5 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 11 am–12 pm

+14126214444

Visit website

Primanti Bros. Restaurant and Bar

4.2 ★ ★ ★ ★ ☆

Near the end, ~12 min detour

Home stretch 4.8 mi from route ~12 min detour $10 to $20

Homestead, Pennsylvania

Hours: 11 am–12 pm

+14124611469

Visit website

Luma | Wine Bar & Restaurant

4.6 ★ ★ ★ ★ ★

Near the end, ~12 min detour

Home stretch 5 mi from route ~12 min detour $40 to $50

Pittsburgh, Pennsylvania

Hours: 4–9 pm

+14123430355

Visit website

Place data sourced from public business listings. Hours and availability may vary.

Heads-up: tricky spots

5 of 15

5 decision points cluster between mile 116.5 and 265 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

6
116.5 mi into trip | ~2h 12m in

Take the exit toward I 99 South, US 220 South, PA 26: Bellefonte

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 161 Toward I 99 South, US 220 South, PA 26: Bellefo...
6
141 mi into trip | ~2h 41m in | I 99; US 220

Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 99 South, US 220 South: Port Matilda,...
8
250.8 mi into trip | ~5h 5m in | I 376; US 22 / Penn-Lincoln Parkway East

Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Toward I 376 West, US 22 West: Pittsburgh
7
264.3 mi into trip | ~5h 23m in

Take the exit toward Second Avenue

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 71B Toward Second Avenue
7
265 mi into trip | ~5h 25m in | Grant Street

Turn right onto Grant Street

Lane positioning matters here

Use the right lane.

Fuel & Cost

Regular Gas

$42.27 one way

$84.54 round trip

$4.05/gal 25.4 MPG avg 93 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.48 $46.78 $93.56
premium $4.81 $50.18 $100.36
diesel $4.80 $50.06 $100.11

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$42

Meals

$25–$50

Total

$67–$92

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 92.8 kg one way. Prices: EIA weekly data, 2026-07-13.

Driving Electric?

About $28 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 79.5 0 $27.84 $12.72
Efficient EV 66.3 0 $23.20 $10.60
EV Truck/SUV 106 1 $37.11 $16.97

Gas CO2

93 kg

EV CO2

31 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Jul 18, 2026

Origin

Wilkes-Barre, PA

Late night in Wilkes-Barre on Monday

Local time

3:20 AM

EDT

Current temp

65°F

Areas Of Smoke

NE 2 mph 1% chance Live forecast

Flood Watch

Flood Watch issued July 18 at 2:13AM EDT until July 19 at 2:00AM EDT by NWS Mount Holly NJ

Beach Hazards Statement

Beach Hazards Statement issued July 17 at 9:22PM EDT until July 18 at 8:00PM EDT by NWS Cleveland OH

Destination

Pittsburgh, PA

Late night in Pittsburgh on Monday

Local time

3:20 AM

EDT

Current temp

71°F

Smoke

S 5 mph 42% chance Live forecast

Flood Watch

Flood Watch issued July 18 at 2:13AM EDT until July 19 at 2:00AM EDT by NWS Mount Holly NJ

Beach Hazards Statement

Beach Hazards Statement issued July 17 at 9:22PM EDT until July 18 at 8:00PM EDT by NWS Cleveland OH

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

6 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 26m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

This route features a highway share of 23%, meaning you'll spend most of your time on surface roads. You'll encounter a long stretch of 98.5 miles on the Keystone Shortway before transitioning to other main roads. Expect a less urban feel for much of the drive, with fewer exits and more continuous cruising once you leave the limited highway sections. The profile is mostly surface roads, indicating a more grounded driving experience.

Only 23% highway — the rest is turn-by-turn surface driving.
24 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 98.5 mi on Keystone Shortway.

How Hard Is This Drive?

8/10

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 116.5 miles in.

Driving Effort 8/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 15 significant decision points across 265.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 116.5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 141 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 250.8 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Elevation Profile

Gently rolling terrain

1,944 ft 547 ft

Total Climb

2,425 ft

Total Descent

2,207 ft

Highest Point

1,944 ft

~189.4 mi in

Elevation Range

1,397 ft

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Wilkes-Barre, PA and Pittsburgh, PA, road signs point toward Altoona and Hollidaysburg.

Altoona

141 mi in | ~2h 41m | via I 99; US 220

Hollidaysburg

174.8 mi in | ~3h 18m

About the Cities

Starting in Wilkes-Barre, PA

Full guide →

Founded 1769

Wilkes-Barre (the last part is variously pronounced "Berry", "Bury", "Bare", or "Berrah" by locals, and "Barry" or "Barr" by others) is a city of 41,000 people (2018) in Northeastern Pennsylvania, approximately 20 miles southwest of Scranton. The city is named for John Wilkes and Isaac Barre, both of whom were members of the British Parliament who opposed royal rule of the colonies. Although the city is named after them, neither one ever set foot in North America.

Top landmarks

  • West End Wheelmen's Club
  • St. Stephen's Episcopal Pro-Cathedral — procathedral in Wilkes-Barre, Pennsylvania
  • River Street Historic District — historic district in Pennsylvania, United States

Arriving in Pittsburgh, PA

Full guide →

Founded 1758

The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.

Top landmarks

  • Carnegie Museum of Natural History — natural history museum in Pittsburgh, Pennsylvania, United States
  • Allegheny Observatory — historic observatory of the University of Pittsburgh
  • Carnegie Museum of Art — museum in Pittsburgh, Pennsylvania

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 5h 26m. Total distance: 265.1 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

5h 26m drive, comfortable solo distance.

Scenic Drive

Mostly surface roads route profile.

Frequently Asked Questions

The longest stretch is about 98.5 miles on Keystone Shortway. The full list of main roads is in the Roads section above.

Yes — we found about 21 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Pittsburgh, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 21 rest areas along the route for bathroom stops.

The main spots that need attention: at 116.5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 141 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 250.8 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Not recommended in a single day. At 5.4 hours each way, a round trip means 10.9 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Pittsburgh, PA before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.

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Explore more options from Wilkes-Barre, PA or browse trips ending in Pittsburgh, PA.

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