Pittsburgh to Damascus is 331.6 miles and takes about 7h via Keystone Shortway, William Penn Highway, and I 99, with a fuel budget near $56 and enough daylight to finish in a day. This trip stays entirely within Pennsylvania, traversing the Northeast region. The route offers a mix of highway cruising and surface road travel, making it a manageable one-day drive. You'll experience a variety of Pennsylvania landscapes as you head towards Damascus.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
165.8 miles from Pittsburgh, PA
A natural place for your longest stop of the day
, about 3h 31m into the drive
.
Main Roads
Road
Distance
Duration
Keystone Shortway
99.3 mi
1h 47m
William Penn Highway
61.6 mi
1h 25m
I 99
57.2 mi
1h 4m
I 81
34.7 mi
42m
Governor Robert P. Casey Highway
15.4 mi
18m
Penn-Lincoln Parkway East
13.8 mi
19m
Admiral Peary Highway
13.7 mi
19m
Roosevelt Highway
11.3 mi
20m
Longest stretch:
Keystone Shortway
— 99.3 mi, about 1h 47m
Traffic on I-80
Hour-of-day weekday pattern from 36 FHWA count stations on your route.
Peak
3 PM
~1,120 veh/hr typical
· worst 1,611
Quietest
2 AM
~194 veh/hr
Peak-to-quiet ratio
5.8×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 104 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Pittsburgh, PA and Damascus, PA.
1
Start on Grant Street
45 ft·9 sec·Grant Street
2
Continue on Grant Street
0.3 mi·1 min·Grant Street
3
Take the ramp
0.4 mi·50 sec
Toward I 376 East: Monroeville
4
Merge onto I 376; US 22; US 30
14 mi·19 min·Penn-Lincoln Parkway East
Use the straight / slight right lanes.
5
Merge onto US 22
45 mi·1 hr 5 min·William Penn Highway
Use the straight / right lanes.
6
Continue on US 22
14 mi·19 min·Admiral Peary Highway
Use the straight / right lanes.
7
Continue on US 22
17 mi·19 min·William Penn Highway
8
Continue on this road
0.5 mi·45 sec·this road
Toward I 99, US 220: Altoona, Bedford
9
Keep slight left at fork
0.9 mi·1 min
Toward I 99 North, US 220 North: Altoona
10
Merge onto I 99; US 220
41 mi·44 min·I 99; US 220
11
Keep slight left at fork onto I 99; US 220; US 322
4.0 mi·4 min·I 99; US 220; US 322
Use the straight lane.
12
Keep slight left at fork onto I 99; US 220
12 mi·14 min·I 99; US 220
Toward I 99 North, US 220 North: Bellefonte
13
Turn left
0.2 mi·31 sec
Toward I 80 East, US 220 North: WilliamsportUse the left lane.
14
Merge onto I 80; US 220
99 mi·1 hr 47 min·Keystone Shortway
15
Take the exit
0.7 mi·1 min
Exit 260BToward I 81 North: Wilkes-Barre
16
Merge onto I 81
35 mi·42 min·I 81
17
Take the exit
0.4 mi·51 sec
Toward I-84 east, US 6 east
18
Keep slight left at fork
0.3 mi·35 sec
19
Keep slight left at fork
0.4 mi·44 sec
Toward US 6 East: Carbondale
20
Continue on US 6
15 mi·18 min·Governor Robert P. Casey Highway
Use the straight lane.
21
Continue on US 6
11 mi·20 min·Roosevelt Highway
Use the straight / right lanes.
22
Continue on US 6
0.9 mi·2 min·West Park Street
23
Turn left onto PA 191
0.6 mi·1 min·Main Street
Use the left lane.
24
Continue on PA 191
0.7 mi·1 min·Fair Avenue
25
Continue on PA 191
9.2 mi·13 min·Hancock Highway
26
Turn right onto PA 371
9.0 mi·15 min·Cochecton Turnpike
27
Turn right onto River Road
130 ft·5 sec·River Road
28
Arrive at destination
River Road
Trip Plan
Given the 7-hour duration, starting your drive from Pittsburgh in the morning is recommended to make the most of daylight. With two planned stops, you can break up the 331.6 miles into manageable segments. The longest stretch without a planned stop is 99.3 miles on the Keystone Shortway, so plan your fuel and rest accordingly. The estimated fuel cost is around $56, so factor that into your budget. Since this is a one-day trip, you have flexibility in timing your stops for breaks or meals.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 165.8 miles from Pittsburgh, PA, or about 3h 31m into the drive.
The longest continuous stretch on this route runs about 99.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 73 miles or 1h 46m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 165.8 miles or 3h 31m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 30m
Traffic, exits, and arrival timing usually matter more near Damascus, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Pittsburgh, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Pittsburgh, PA
This is one driving day of about 331.6 miles and 7h.
Your first comfortable stop window is around 73 miles from Pittsburgh, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on Keystone Shortway for about 99.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 18
5 decision points cluster between mile 0.7 and 148.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.7 mi into trip|~2m in|I 376; US 22; US 30 / Penn-Lincoln Parkway East
Merge onto I 376; US 22; US 30 / Penn-Lincoln Parkway East
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
6
90.2 mi into trip|~2h 7m in
Keep slight left at fork toward I 99 North, US 220 North: Altoona
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 99 North, US 220 North: Altoona
6
132.1 mi into trip|~2h 53m in|I 99; US 220; US 322
Keep slight left at fork onto I 99; US 220; US 322
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight lane.
6
136 mi into trip|~2h 57m in|I 99; US 220
Keep slight left at fork onto I 99; US 220 toward I 99 North, US 220 North: Bellefonte
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 99 North, US 220 North: Bellefonte
7
148.4 mi into trip|~3h 12m in
Turn left toward I 80 East, US 220 North: Williamsport
Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Toward I 80 East, US 220 North: Williamsport
Fuel & Cost
Regular Gas
$58.36 one way
$116.71 round trip
$4.47/gal25.4 MPG avg116 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.89
$63.81
$127.63
premium
$5.23
$68.23
$136.45
diesel
$6.18
$80.67
$161.34
Estimated Tolls: $0.63
Cochecton Turnpike
(9 mi)$0.63
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$58
Tolls
$1
Meals
$25–$50
Total
$84–$109
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 116 kg one way.
Prices: EIA weekly data, 2026-10-12.
Driving Electric?
About $35 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
99.5
1
$34.82
$15.92
Efficient EV
82.9
0
$29.02
$13.26
EV Truck/SUV
132.6
1
$46.42
$21.22
Gas CO2
116 kg
EV CO2
39 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Oct 17, 2026
Origin
Pittsburgh, PA
Morning
in Pittsburgh on Sunday
Local time
6:19 AM
EDT
Current temp
30°F
Clear then Widespread Frost
N 0 to 7 mph0% chanceLive forecast
Freeze Warning
Freeze Warning issued October 17 at 1:21PM EDT until October 18 at 9:00AM EDT by NWS Cleveland OH
Freeze Warning
Freeze Warning issued October 17 at 1:03PM EDT until October 18 at 9:00AM EDT by NWS Binghamton NY
Destination
Damascus, PA
Morning
in Damascus on Sunday
Local time
6:19 AM
EDT
Current temp
29°F
Clear
NW 1 to 6 mph0% chanceLive forecast
Freeze Warning
Freeze Warning issued October 17 at 1:21PM EDT until October 18 at 9:00AM EDT by NWS Cleveland OH
Freeze Warning
Freeze Warning issued October 17 at 1:03PM EDT until October 18 at 9:00AM EDT by NWS Binghamton NY
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
7h on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Johnstown Flood National Memorial
National Memorial
The South Fork Dam failed on Friday, May 31, 1889, and unleashed 20,000,000 tons of water that devastated Johnstown, PA. The flood killed 2,209 people but it brought the nation and the world together...
8 mi from route
~19 min detour
Free
near mile 68.6
On Tuesday morning, September 11, 2001, the U.S. came under attack when four commercial airliners were hijacked and used to strike targets on the ground. Nearly 3,000 people tragically lost their live...
27 mi from route
~68 min detour
Free
near mile 57.2
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
About 35% of this 331.6-mile route is on highways. You'll encounter a stretch of 99.3 miles on the Keystone Shortway before transitioning to other roads. Expect a mix of highway driving and surface roads, which means you'll see fewer exits and more varied scenery after leaving the main highways. This profile suggests a blend of efficient travel and more local road experiences.
35% highway, the rest on surface roads — varied driving throughout.
28 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 99.3 mi on Keystone Shortway.
How Hard Is This Drive?
9/10
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.7 miles in near I 376; US 22; US 30 / Penn-Lincoln Parkway East.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 331.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.7 miles (I 376; US 22; US 30 / Penn-Lincoln Parkway East): Merge point - match speed before joining. Lane positioning matters here; at 90.2 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 132.1 miles (I 99; US 220; US 322): Highway fork - watch signs carefully. Lane positioning matters here.
Elevation Profile
Gently rolling terrain
2,136 ft565 ft
Total Climb
2,619 ft
Total Descent
2,647 ft
Highest Point
2,136 ft
~71 mi in
Elevation Range
1,572 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Pittsburgh, PA to Damascus, PA, road signs begin pointing toward Bedford along the way.
The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.
Top landmarks
•Carnegie Museum of Natural History — natural history museum in Pittsburgh, Pennsylvania, United States
•Carnegie Museum of Art — museum in Pittsburgh, Pennsylvania
•Andy Warhol Museum — art museum in Pittsburgh, Pennsylvania
Doable as a same-day drive at 7h. Total distance: 331.6 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h drive, plan rest stops for pacing.
Scenic Drive
Mixed highway & surface route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 99.3 miles on Keystone Shortway. The full list of main roads is in the Roads section above.
Expect about $0.63 in tolls one way, starting with Cochecton Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
Yes — we found about 24 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Damascus, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. There are 24 rest areas along the route for bathroom stops.
The main spots that need attention: at 0.7 miles (I 376; US 22; US 30 / Penn-Lincoln Parkway East): Merge point - match speed before joining. Lane positioning matters here; at 90.2 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 132.1 miles (I 99; US 220; US 322): Highway fork - watch signs carefully. Lane positioning matters here.
Yes — Johnstown Flood National Memorial and Flight 93 National Memorial. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 7.0 hours each way, a round trip means 14.0 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Damascus, PA before the return drive.
