St. Louis to Seymour is 209.7 miles and takes about 4h 3m via Henry Shaw Ozark Corridor and US 60, with a fuel budget near $37 and enough daylight to finish in a day. This trip stays within Missouri, moving from the Midwest region to another part of the Midwest. It's a single-day drive, mostly on surface roads, so you'll experience a more local feel rather than high-speed interstate travel. Consider this route if you prefer a less hurried pace and want to see more of the Missouri landscape directly.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
104.8 miles from St. Louis, MO
A natural place for your longest stop of the day
, about 1h 58m into the drive
.
Main Roads
Road
Distance
Duration
Henry Shaw Ozark Corridor
174 mi
3h 9m
South Marshall Street
12.2 mi
17m
US 60
4 mi
4m
Police Officer Ernest M. Brockman Sr. Memorial Highway
3.5 mi
4m
Officer Michael Barwick Memorial Highway
3.5 mi
4m
Police Officer Robert Stanze Memorial Highway
2.7 mi
3m
Officer David Haynes Memorial Highway
2.3 mi
3m
South Jefferson Avenue
1.2 mi
2m
Longest stretch:
Henry Shaw Ozark Corridor
— 174 mi, about 3h 9m
Traffic on I-44
Hour-of-day weekday pattern from 18 FHWA count stations on your route.
Peak
4 PM
~2,661 veh/hr typical
· worst 3,288
Quietest
2 AM
~182 veh/hr
Peak-to-quiet ratio
14.6×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis, MO and Seymour, MO.
1
Start on Market Street
1.0 mi·2 min·Market Street
2
Turn left onto South Jefferson Avenue
1.2 mi·2 min·South Jefferson Avenue
3
Take the ramp
0.2 mi·17 sec
Toward I 44 West
4
Merge onto I 44
2.3 mi·3 min·Officer David Haynes Memorial Highway
5
Continue on I 44
3.5 mi·4 min·Officer Michael Barwick Memorial Highway
6
Continue on I 44
2.7 mi·3 min·Police Officer Robert Stanze Memorial Highway
7
Continue on I 44
3.5 mi·4 min·Police Officer Ernest M. Brockman Sr. Memorial Highway
8
Continue on I 44; US 50
174 mi·3 hr 9 min·Henry Shaw Ozark Corridor
Use the straight / slight right lanes.
9
Take the exit
0.3 mi·33 sec
10
Enter roundabout onto MO CC
416 ft·8 sec·MO CC
11
Continue on MO CC
486 ft·9 sec·MO CC
12
Enter roundabout onto North Marshall Road
119 ft·2 sec·North Marshall Road
13
Continue on North Marshall Road
0.3 mi·49 sec·North Marshall Road
14
Continue on North Marshall Street
0.8 mi·2 min·North Marshall Street
15
Turn left onto US Historic 66
0.3 mi·32 sec·East Hubble Drive
16
Turn sharp right onto North Pine Street
0.9 mi·2 min·North Pine Street
17
Turn right onto MO 38
0.2 mi·32 sec·Commercial Street
18
Turn left onto MO A
12 mi·17 min·South Marshall Street
19
At end of road, turn left
0.5 mi·1 min
20
Continue on West Springfield Avenue
430 ft·21 sec·West Springfield Avenue
21
Turn right onto North Diggins Main Street
241 ft·16 sec·North Diggins Main Street
22
Turn left onto US 60
4.0 mi·4 min·US 60
23
Turn right
471 ft·9 sec
24
Turn straight onto West Clinton Avenue
1.1 mi·1 min·West Clinton Avenue
25
Turn right onto MO K
0.2 mi·26 sec·North Main Street
26
Turn right onto West Washington Street
165 ft·7 sec·West Washington Street
27
Arrive at destination
West Washington Street
Trip Plan
Given the 4-hour drive time, leaving St. Louis in the morning should give you ample time to reach Seymour comfortably. Since this is a single-day trip and the longest stretch is 174 miles, you can be flexible with stops. Plan for one stop to break up the drive, perhaps around the halfway point, to refuel and stretch your legs. Keep an eye on your fuel gauge, especially before heading into more rural stretches, as gas stations might be spaced further apart. The fuel cost estimate is around $37, so budget accordingly.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 104.8 miles from St. Louis, MO, or about 1h 58m into the drive.
The longest continuous stretch on this route runs about 174 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 46 miles or 54m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 104.8 miles or 1h 58m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 11m
Traffic, exits, and arrival timing usually matter more near Seymour, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving St. Louis, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from St. Louis, MO
This is one driving day of about 209.7 miles and 4h 3m.
Your first comfortable stop window is around 46 miles from St. Louis, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Henry Shaw Ozark Corridor for about 174 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 188.7 and 204.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
188.7 mi into trip|~3h 29m in|MO CC
Enter roundabout onto MO CC
Roundabout - know your exit number before entering
6
188.9 mi into trip|~3h 30m in|North Marshall Road
Enter roundabout onto North Marshall Road
Roundabout - know your exit number before entering
5
190.3 mi into trip|~3h 33m in|North Pine Street
Turn sharp right onto North Pine Street
Sharp turn - reduce speed on approach
5
203.6 mi into trip|~3h 53m in
At end of road, turn left
Navigation decision point
5
204.2 mi into trip|~3h 56m in|North Diggins Main Street
Turn right onto North Diggins Main Street
Navigation decision point
Fuel & Cost
Regular Gas
$30.97 one way
$61.94 round trip
$3.75/gal25.4 MPG avg73 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.14
$34.19
$68.38
premium
$4.72
$38.93
$77.87
diesel
$4.80
$39.60
$79.19
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$31
Meals
$25–$50
Total
$56–$81
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 73.4 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $22 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
62.9
0
$22.02
$10.07
Efficient EV
52.4
0
$18.35
$8.39
EV Truck/SUV
83.9
1
$29.36
$13.42
Gas CO2
73 kg
EV CO2
25 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 19, 2026
Origin
St. Louis, MO
Morning
in St. Louis on Sunday
Local time
6:03 AM
CDT
Current temp
77°F
Partly Cloudy then Slight Chance Showers And Thunderstorms
W 2 to 8 mph19% chanceLive forecast
Special Weather Statement
Special Weather Statement issued July 18 at 7:18PM CDT by NWS Memphis TN
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 18 at 8:00PM CDT by NWS Memphis TN
Destination
Seymour, MO
Morning
in Seymour on Sunday
Local time
6:03 AM
CDT
Current temp
71°F
Slight Chance Showers And Thunderstorms
SW 6 mph18% chanceLive forecast
Special Weather Statement
Special Weather Statement issued July 18 at 7:18PM CDT by NWS Memphis TN
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 18 at 8:00PM CDT by NWS Memphis TN
89°F
Cuba, MO
105 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
6 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 3m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Your drive will primarily be on surface roads, covering 174 miles on the Henry Shaw Ozark Corridor before transitioning. With a highway share of only 2, expect a more relaxed pace for most of the trip. You'll likely notice more local traffic and frequent changes in speed limits as you move through towns. The longest continuous stretch on a single road is 174 miles, indicating a significant portion of the drive will be on one main corridor.
Only 2% highway — the rest is turn-by-turn surface driving.
27 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 174 mi on Henry Shaw Ozark Corridor.
How Hard Is This Drive?
3/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way. The trickiest moment comes around 188.7 miles in near MO CC.
Driving Effort3/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 4h 3m drive. You will face about 16 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 188.7 miles (MO CC): Roundabout - know your exit number before entering; at 188.9 miles (North Marshall Road): Roundabout - know your exit number before entering; at 190.3 miles (North Pine Street): Sharp turn - reduce speed on approach.
The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. The city's planners have created an aesthetically beautiful city, with plenty of green space amidst buildings both old and new, framed by the majestic Mississippi and Missouri rivers. And capping it all is the world's tallest man-made monument, the beautiful and iconic Gateway Arch.
St. Louis is a city of culture and surprisingly inexpensive. Among American cities, only Washington, D.C. has more free attractions for tourists and residents alike. Hotels, restaurants, and even parking garages avoid the premium pricing common in other big cities. Although often overlooked, St. Louis can be an affordable, educational, and fun family getaway.
Top landmarks
•Gateway Arch — monument in St. Louis, Missouri
•Missouri Botanical Garden — non-profit organization in the USA
•Gateway Arch National Park — American National Park in St. Louis, Missouri
Mostly surface roads route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 174 miles on Henry Shaw Ozark Corridor. The full list of main roads is in the Roads section above.
Yes — we found about 18 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 188.7 miles (MO CC): Roundabout - know your exit number before entering; at 188.9 miles (North Marshall Road): Roundabout - know your exit number before entering; at 190.3 miles (North Pine Street): Sharp turn - reduce speed on approach.
Yes — Gateway Arch National Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.1 hours each way, an in-and-out day trip would put you behind the wheel for 8.1 hours — manageable with a long break at Seymour, MO, but most travelers stay overnight.
