Sherrill, MO to Saint Joseph, MO is 303.7 miles and takes about 5h 56m via US 63, with a fuel budget near $46 and enough daylight to finish in a day. This trip stays within the Midwest, traversing Missouri for its entirety. You'll experience a mix of highway cruising and surface road driving, making it a manageable one-day excursion. Plan for a straightforward drive that's well within reach for a single day's travel.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
151.8 miles from Sherrill, MO
A natural place for your longest stop of the day
, about 3h 8m into the drive
.
Main Roads
Road
Distance
Duration
US 63
100.6 mi
2h 4m
U.S. Submarine Veterans' Memorial Highway
54.4 mi
58m
Dwight D. Eisenhower Highway
54.3 mi
58m
I 29
26 mi
27m
I 435
20.9 mi
22m
Lamar Hunt Memorial Highway
7.8 mi
9m
MO E
7.5 mi
10m
MO A
7.5 mi
10m
Longest stretch:
US 63
— 100.6 mi, about 2h 4m
Traffic on I-70
Hour-of-day weekday pattern from 13 FHWA count stations on your route.
Peak
4 PM
~4,251 veh/hr typical
Quietest
2 AM
~346 veh/hr
Peak-to-quiet ratio
12.3×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Sherrill, MO and Saint Joseph, MO.
1
Start on Shafer Road
0.2 mi·1 min·Shafer Road
2
Turn left onto MO CC
0.8 mi·1 min·MO CC
3
Continue on US 63; MO CC
28 mi·35 min·US 63; MO CC
Use the left / straight lanes.
4
Continue on I 44 Business; US Historic 66; US 63
287 ft·4 sec·North Bishop Avenue
5
Keep slight left at fork onto I 44 Business; US Historic 66; US 63
183 ft·3 sec·North Bishop Avenue
6
Keep slight right at fork onto MO E
0.4 mi·48 sec·Tim Bradley Way
7
Enter roundabout onto MO E
181 ft·3 sec·MO E
8
Continue on MO E
7.5 mi·10 min·MO E
9
Turn right onto MO A
7.5 mi·10 min·MO A
10
Turn left onto US 63; MO 28
45 mi·58 min·US 63; MO 28
11
Take the exit onto US 63
0.3 mi·40 sec·US 63
Toward US 54 East, US 63 North: Fulton, Columbia
12
Merge onto US 54; US 63
1.4 mi·1 min·US 54; US 63
13
Take the exit onto US 63
28 mi·30 min·US 63
Toward US 63 North: Columbia
14
Take the exit
0.4 mi·42 sec
Toward I 70, US 40, MO PP: Kansas City, Saint LouisUse the left / straight / slight right lanes.
15
Continue on US 63 Conn
0.2 mi·31 sec·US 63 Conn
Use the straight lane.
16
Take the exit
0.4 mi·54 sec
Toward I 70 West, US 40 West: Kansas CityUse the left lane.
17
Merge onto I 70; US 40
1.3 mi·1 min·Sheriff Roger I. Wilson Memorial Highway
18
Continue on I 70; US 40
1.6 mi·1 min·Highway Patrol Sgt. Benjamin Booth Memorial Highway
19
Continue on I 70; US 40
1.8 mi·2 min·Dwight D. Eisenhower Highway
20
Continue on I 70; US 40
54 mi·58 min·U.S. Submarine Veterans' Memorial Highway
Exit 8BToward I 435 North, US 24 East: Des MoinesUse the straight / slight right lanes.
27
Merge onto I 435; US 24
7.8 mi·9 min·Lamar Hunt Memorial Highway
28
Continue on I435 N
1.3 mi·1 min·I435 N
29
Continue on I 435
21 mi·22 min·I 435
30
Keep slight left at fork onto I 29; US 71
26 mi·27 min·I 29; US 71
Toward I 29 North, US 71 North: Saint Joseph
31
Take the exit
0.5 mi·54 sec
Exit 43Toward I 229 North: Downtown Saint Joseph
32
Continue on I 229
5.7 mi·6 min·I 229
33
Take the exit
0.3 mi·33 sec
Exit 6AToward Central Business District
34
Continue on Edmond Street
0.5 mi·57 sec·Edmond Street
35
Turn left onto I 29 Business
0.2 mi·20 sec·South 10th Street
36
Turn right onto I 29 Business
379 ft·6 sec·Frederick Avenue
37
Turn slight right onto Walter Welsh Avenue
137 ft·2 sec·Walter Welsh Avenue
38
Arrive at destination
Walter Welsh Avenue
Trip Plan
Given the 5-hour 56-minute estimated drive time, you can comfortably complete this trip in one day. Aim for an early morning departure from Sherrill, MO, to maximize daylight and allow for an unhurried arrival in Saint Joseph, MO. With only one recommended stop, you have flexibility in pacing your journey. Keep an eye on your fuel, especially during the 100.6-mile stretch on US 63, as services might be less frequent. The $46 fuel cost estimate is a helpful benchmark for budgeting.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 151.8 miles from Sherrill, MO, or about 3h 8m into the drive.
The longest continuous stretch on this route runs about 100.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 67 miles or 1h 29m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 151.8 miles or 3h 8m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 56m
Traffic, exits, and arrival timing usually matter more near Saint Joseph, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Sherrill, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Sherrill, MO
This is one driving day of about 303.7 miles and 5h 56m.
Your first comfortable stop window is around 67 miles from Sherrill, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 63 for about 100.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 19
5 decision points cluster between mile 29 and 270.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
29 mi into trip|~38m in|I 44 Business; US Historic 66; US 63 / North Bishop Avenue
Keep slight left at fork onto I 44 Business; US Historic 66; US 63 / North Bishop Avenue
Highway fork - watch signs carefully
7
118.6 mi into trip|~2h 31m in
Take the exit toward I 70, US 40, MO PP: Kansas City, Saint Louis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the left / straight / slight right lanes.
Toward I 70, US 40, MO PP: Kansas City, Saint L...
9
119.2 mi into trip|~2h 32m in
Take the exit toward I 70 West, US 40 West: Kansas City
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Toward I 70 West, US 40 West: Kansas City
8
239.4 mi into trip|~4h 43m in
Take the exit toward I 435 North, US 24 East: Des Moines
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 8B
Toward I 435 North, US 24 East: Des Moines
6
270.5 mi into trip|~5h 19m in|I 29; US 71
Keep slight left at fork onto I 29; US 71 toward I 29 North, US 71 North: Saint Joseph
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 29 North, US 71 North: Saint Joseph
Fuel & Cost
Regular Gas
$44.85 one way
$89.70 round trip
$3.75/gal25.4 MPG avg106 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.14
$49.51
$99.03
premium
$4.72
$56.39
$112.78
diesel
$4.80
$57.34
$114.69
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$45
Meals
$25–$50
Total
$70–$95
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 106.3 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $32 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
91.1
1
$31.89
$14.58
Efficient EV
75.9
0
$26.57
$12.15
EV Truck/SUV
121.5
1
$42.52
$19.44
Gas CO2
106 kg
EV CO2
36 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 17, 2026
Origin
Sherrill, MO
Morning
in Sherrill on Sunday
Local time
9:41 AM
CDT
Current temp
89°F
Slight Chance Showers And Thunderstorms
W 7 mph15% chanceLive forecast
Special Weather Statement
Special Weather Statement issued July 17 at 2:27PM CDT by NWS Quad Cities IA IL
Special Weather Statement
Special Weather Statement issued July 17 at 2:25PM CDT by NWS Quad Cities IA IL
Destination
Saint Joseph, MO
Morning
in Saint Joseph on Sunday
Local time
9:41 AM
CDT
Current temp
91°F
Slight Chance Showers And Thunderstorms
SSW 9 mph17% chanceLive forecast
Special Weather Statement
Special Weather Statement issued July 17 at 2:27PM CDT by NWS Quad Cities IA IL
Special Weather Statement
Special Weather Statement issued July 17 at 2:25PM CDT by NWS Quad Cities IA IL
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 56m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This route involves a 51% highway share, meaning you'll have substantial stretches on faster roads. The longest continuous segment on US 63 spans 100.6 miles, offering a good period of consistent cruising. Expect to transition between the U.S. Submarine Veterans' Memorial Highway and Dwight D. Eisenhower Highway onto surface roads as you progress. The profile is mixed highway and surface, so be prepared for changes in speed limits and road conditions.
51% highway, the rest on surface roads — varied driving throughout.
38 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 100.6 mi on US 63.
How Hard Is This Drive?
10/10
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 29 miles in near I 44 Business; US Historic 66; US 63 / North Bishop Avenue.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 19 significant decision points across 303.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 29 miles (I 44 Business; US Historic 66; US 63 / North Bishop Avenue): Highway fork - watch signs carefully; at 118.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 119.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
1,197 ft619 ft
Total Climb
519 ft
Total Descent
822 ft
Highest Point
1,197 ft
Elevation Range
578 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Sherrill, MO and Saint Joseph, MO, road signs point toward Columbia, Mo Pp: Kansas City and Saint Louis.
Doable as a same-day drive at 5h 56m. Total distance: 303.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 56m drive, comfortable solo distance.
Frequently Asked Questions
The longest stretch is about 100.6 miles on US 63. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Saint Joseph, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 29 miles (I 44 Business; US Historic 66; US 63 / North Bishop Avenue): Highway fork - watch signs carefully; at 118.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 119.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Not recommended in a single day. At 5.9 hours each way, a round trip means 11.9 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Saint Joseph, MO before the return drive.
