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Trip Overview
Sanford, ME to Medway, ME is 222.7 miles and takes about 4h 10m via Maine Turnpike and I-295, with a fuel budget near $40 and enough daylight to finish in a day. This trip stays within Maine, moving from the southern part of the state up through its central region. Given the relatively short duration and consistent highway travel, it’s a straightforward drive suitable for a single day. You'll find the bulk of the miles are on major interstates, making for efficient travel between these two points.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
111.3 miles from Sanford, ME
A natural place for your longest stop of the day
, about 2h 9m into the drive
.
Main Roads
Road
Distance
Duration
Maine Turnpike
153.1 mi
2h 42m
I 295
52.5 mi
1h 1m
Alfred Road
8.2 mi
9m
Sanford Road
2.4 mi
3m
Biddeford Road
1.8 mi
2m
Alfred Street
1.4 mi
1m
Cottage Street
1.2 mi
3m
Medway Road
0.6 mi
1m
Longest stretch:
Maine Turnpike
— 153.1 mi, about 2h 42m
Traffic on I-295
Hour-of-day weekday pattern from 39 FHWA count stations on your route.
Peak
4 PM
~2,557 veh/hr typical
· worst 3,064
Quietest
2 AM
~87 veh/hr
Peak-to-quiet ratio
29.4×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Sanford, ME and Medway, ME.
1
Start on this road
89 ft·8 sec·this road
2
Turn right onto Washington Street
0.1 mi·23 sec·Washington Street
3
Continue on River Street
0.2 mi·26 sec·River Street
4
Turn right onto US 202; ME 4A
1.2 mi·3 min·Cottage Street
5
Continue on US 202; ME 4A
2.4 mi·3 min·Sanford Road
6
Continue on ME 111
1.8 mi·2 min·Biddeford Road
Use the left / straight / right lanes.
7
Continue on ME 111
8.2 mi·9 min·Alfred Road
8
Continue on ME 111
1.4 mi·1 min·Alfred Street
9
Take the ramp
0.1 mi·1 min
Use the straight / left lanes.
10
Keep slight right at fork
0.2 mi·33 sec
Toward I 95 North Toll: Portland, Augusta
11
Merge onto I 95
12 mi·13 min·Maine Turnpike
12
Keep slight right at fork onto I 295
52 mi·1 hr 1 min·I 295
Exit 44Toward Downtown PortlandUse the slight right lane.
13
Merge onto I 95
141 mi·2 hr 29 min·Maine Turnpike
14
Take the exit
0.2 mi·37 sec
Exit 244Toward ME 157: Medway, Millinocket
15
Keep slight left at fork
94 ft·3 sec
16
Turn left onto ME 157
0.6 mi·1 min·Medway Road
17
Turn sharp left onto Town Road
431 ft·20 sec·Town Road
18
Turn right onto Village Lane
0.1 mi·26 sec·Village Lane
19
Turn right onto Schoolhouse Road
228 ft·10 sec·Schoolhouse Road
20
Continue on School Street
0.1 mi·31 sec·School Street
21
At end of road, turn right onto Main Road
168 ft·7 sec·Main Road
22
Arrive at destination
Main Road
Trip Plan
For this 4h 10m drive, leaving Sanford in the morning will give you ample time to reach Medway comfortably. Since it’s a single-day trip, you have flexibility in departure time. The $40 fuel estimate is based on the 222.7 miles, so ensure your tank is full before you leave or plan a stop. The longest stretch without a major change in road type is over 150 miles, so plan your first break around the midpoint of your highway driving to stretch your legs. Watch for the transition from highway to local roads as you near Medway.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 111.3 miles from Sanford, ME, or about 2h 9m into the drive.
The longest continuous stretch on this route runs about 153.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 1h in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 111.3 miles or 2h 9m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 25m
Traffic, exits, and arrival timing usually matter more near Medway, ME than in the middle of the route.
Before You Leave
+
Open the route before leaving Sanford, ME so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Sanford, ME
This is one driving day of about 222.7 miles and 4h 10m.
Your first comfortable stop window is around 49 miles from Sanford, ME.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Maine Turnpike for about 153.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 14
5 decision points cluster between mile 15.5 and 222.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
15.5 mi into trip|~22m in
Keep slight right at fork toward I 95 North Toll: Portland, Augusta
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 95 North Toll: Portland, Augusta
8
28 mi into trip|~35m in|I 295
Keep slight right at fork onto I 295 toward Downtown Portland
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Exit 44
Toward Downtown Portland
6
221.4 mi into trip|~4h 6m in
Take the exit toward ME 157: Medway, Millinocket
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 244
Toward ME 157: Medway, Millinocket
5
221.6 mi into trip|~4h 7m in
Keep slight left at fork
Highway fork - watch signs carefully
5
222.3 mi into trip|~4h 8m in|Town Road
Turn sharp left onto Town Road
Sharp turn - reduce speed on approach
Fuel & Cost
Regular Gas
$39.37 one way
$78.73 round trip
$4.49/gal25.4 MPG avg78 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.92
$43.12
$86.24
premium
$5.29
$46.37
$92.74
diesel
$5.35
$46.91
$93.81
Estimated Tolls: $9.19
Maine Turnpike
(153.1 mi)$9.19
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$39
Tolls
$9
Meals
$25–$50
Total
$74–$99
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 77.9 kg one way.
Prices: EIA weekly data, 2026-06-01.
Driving Electric?
About $23 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
66.8
0
$23.38
$10.69
Efficient EV
55.7
0
$19.49
$8.91
EV Truck/SUV
89.1
1
$31.18
$14.25
Gas CO2
78 kg
EV CO2
26 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jun 1, 2026
Origin
Sanford, ME
Afternoon
in Sanford on Wednesday
Local time
3:06 PM
EDT
Current temp
45°F
Scattered Rain Showers
NE 5 mph51% chanceLive forecast
Destination
Medway, ME
Afternoon
in Medway on Wednesday
Local time
3:06 PM
EDT
Current temp
36°F
Areas Of Frost
N 2 mph2% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
9 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 10m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Frances Perkins National Monument
National Monument
Known as the first woman to hold a presidential cabinet position and the “Woman behind the New Deal,” Frances Perkins championed many labor rights that Americans enjoy today, including safety standard...
17 mi from route
~41 min detour
Free
near mile 69.1
Spread across a wild landscape offering spectacular views of Katahdin, Katahdin Woods and Waters invites discovery of its rivers, streams, woods, flora, fauna, geology, and the night skies that have a...
26 mi from route
~64 min detour
Free
near mile 222.7
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
You'll spend most of your time on highways, with 92% of the drive utilizing major roads like the Maine Turnpike and I-295. The longest continuous stretch on these highways is 153.1 miles. After this extended highway portion, you'll transition to surface roads, so expect a change in pace and potentially more local traffic as you approach your destination. Keep an eye out for the increase in exit activity as you get closer to populated areas.
92% highway — fuel and pacing are the main things to plan.
22 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 153.1 mi on Maine Turnpike.
How Hard Is This Drive?
7/10
This is a straightforward highway drive that stays mostly on Maine Turnpike and I 295. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 15.5 miles in.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 222.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 15.5 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 28 miles (I 295): Highway fork - watch signs carefully. Lane positioning matters here; at 221.4 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
486 ft21 ft
Total Climb
721 ft
Total Descent
747 ft
Highest Point
486 ft
~143.1 mi in
Elevation Range
464 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Sanford, ME and Medway, ME, road signs point toward Augusta and Portland.
Doable as a same-day drive at 4h 10m. Total distance: 222.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 10m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (92%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 153.1 miles on Maine Turnpike. The full list of main roads is in the Roads section above.
Expect about $9.19 in tolls one way, starting with Maine Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
Yes — we found about 9 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Medway, ME before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 9 rest areas along the route for bathroom stops.
Mostly yes along the main roads, but rural stretches through ME can have sparse or no coverage. Before you leave, download offline Google Maps or Apple Maps for the route, and consider downloading music or podcasts instead of streaming. If you depend on data for navigation, keep a paper backup of the turn-by-turn directions.
The main spots that need attention: at 15.5 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 28 miles (I 295): Highway fork - watch signs carefully. Lane positioning matters here; at 221.4 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Yes — Frances Perkins National Monument and Katahdin Woods and Waters National Monument. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.2 hours each way, an in-and-out day trip would put you behind the wheel for 8.3 hours — manageable with a long break at Medway, ME, but most travelers stay overnight.
